Louisville vs. Jacksonville State Prediction, Odds, Picks - September 7, 2024

Updated Sep. 7, 2024 3:05 p.m. ET

Data Skrive

The No. 22 Louisville Cardinals (1-0) are an overwhelming 28.5-point favorite heading into their matchup on Saturday, September 7, 2024 against the Jacksonville State Gamecocks (0-1). The over/under is set at 56.5.

The Cardinals beat the Austin Peay Governors, 62-0, in their most recent game. In their last game, the Gamecocks lost against the Coastal Carolina Chanticleers, 55-27.

Keep up with college football all season on FOX Sports.

Caleb Williams-Bears, Bucs, Bills are on Upset Alert in Week 1 | First Things First

Nick Wright, Chris Broussard, Kevin Wildes and Coach Eric Mangini reveal the first edition of Upset Alert of the 2024 season, featuring the Chicago Bears, Tampa Bay Bucs and Buffalo Bills.

Louisville vs. Jacksonville State Game Information & Odds

When: Saturday, September 7, 2024 at 3:30 p.m. ET
Location: L&N Federal Credit Union Stadium in Louisville, Kentucky
TV: ACC Network Extra
Live Box Score on FOX Sports

Louisville vs Jacksonville State Betting Information updated as of September 7, 2024, 2:46 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Louisville	-28.5 (-111)	-8333	+1930	56.5	-111	-109

Louisville vs. Jacksonville State Prediction

Pick ATS: Jacksonville State (+28.5)
Pick OU: Under (56.5)
Prediction: Louisville 34, Jacksonville State 18

Predictions are made by the Data Skrive betting model.

Learn more about the Louisville Cardinals vs. the Jacksonville State Gamecocks game on FOX Sports!

Louisville vs. Jacksonville State Betting Insights

Per the spread and over/under, the implied score for the matchup is Cardinals 42, Gamecocks 14.
The Cardinals have a 98.8% chance to claim victory in this meeting per the moneyline's implied probability. The Gamecocks hold a 4.9% implied probability.
Louisville covered six times in 14 games with a spread last season.
Jacksonville State has not won against the spread this season in one games with a spread.

Louisville vs. Jacksonville State: 2024 Stats Comparison

	Louisville	Jacksonville State
Off. Points per Game (Rank)	62 (11)	27 (90)
Def. Points per Game (Rank)	0 (1)	55 (128)
Turnovers Allowed (Rank)	0 (1)	3 (113)
Turnovers Forced (Rank)	2 (24)	2 (24)

Louisville 2024 Key Players

Name	Position	Stats
Tyler Shough	QB	232 YDS (75%) / 4 TD / 0 INT
Isaac Brown	RB	123 YDS / 1 TD / 123 YPG / 24.6 YPC
Jadon Thompson	WR	3 REC / 44 YDS / 2 TD / 44 YPG
Duke Watson	RB	86 YDS / 1 TD / 86 YPG / 14.3 YPC
Tramel Logan	DL	2 TKL / 1 TFL / 2 SACK
Tamarion McDonald	DB	2 TKL / 2 TFL / 2 SACK
Thor Griffith	DL	1 TKL / 1 TFL / 1 SACK
Ashton Gillotte	DL	1 TKL / 1 TFL / 1 SACK

Jacksonville State 2024 Key Players

Name	Position	Stats
Mike Pettway	WR	1 REC / 92 YDS / 1 TD / 92 YPG
Tre Stewart	RB	62 YDS / 1 TD / 62 YPG / 15.5 YPC 1 REC / 17 REC YDS / 0 REC TD / 17 REC YPG
Tyler Huff	QB	173 YDS (50%) / 1 TD / 2 INT 11 RUSH YDS / 0 RUSH TD / 11 RUSH YPG
Cole Fuller	TE	0 REC / 0 YDS / 0 TD / 0 YPG
Zechariah Poyser	DB	0 TKL / 0 TFL / 1 INT / 1 PD
Tyler Huff	QB	0 TKL / TFL
Laletia Hale	LB	1 TKL / 0 TFL
Will O'Steen	OL	0 TKL / TFL