Houston vs. Duke Prediction, Odds, Picks - NCAA Tournament Sweet 16

Updated Mar. 29, 2024 8:27 p.m. ET

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A Sweet 16 battle will feature the No. 1 seed Houston Cougars (32-4) and the No. 4 seed Duke Blue Devils (26-8) playing on Friday at American Airlines Center. The NCAA Tournament contest begins at 9:39 PM ET.

The Cougars are a 4.5-point favorite against the Blue Devils when the Cougars and the Blue Devils meet. The game's over/under is set at 133.5.

Continue scrolling to get all you need to know ahead of betting on the Houston-Duke contest.

Houston vs. Duke Game Information & Odds

• When: Friday, March 29, 2024 at 9:39 PM ET
• Where: American Airlines Center in Dallas, Texas
• How to Watch on TV: CBS
• Live boxscore on FOX Sports

Houston vs. Duke Prediction

• Pick ATS: Duke (+4.5)
  
• Pick OU: Over (133.5)
  
• Prediction: Houston 71, Duke 68

Learn more about the Houston Cougars vs. the Duke Blue Devils game on FOX Sports!

Houston vs. Duke Betting Insights

Betting Line Implied Predictions

• Based on the spread and over/under, the implied score for the matchup is Cougars 69, Blue Devils 64.
• The Cougars have a 68.6% chance to win this game based on the moneyline's implied probability.
• The Blue Devils have a 35.7% implied probability to come out on top.

Key Spread Facts

• Houston has compiled an 18-16-1 ATS record so far this year.
• Duke has won 19 games against the spread this season, while failing to cover or pushing 13 times.
• Houston has an ATS record of 16-13-1 when playing as at least 4.5-point favorites this season.
• Duke has not covered the spread when an underdog by 4.5 points or more this year (in one opportunity).

Key Total Facts

• Cougars games have finished with more than 133.5 points 14 times so far this year.
• Blue Devils games have gone over 133.5 points on 28 occasions this year.
• The total for this matchup is 133.5 points, 20.4 fewer than the combined scoring average of the two teams.

Key Moneyline Facts

• Houston has won 22 of 26 games when the moneyline favorite this season (84.6%).
• Duke has lost both games it has played as underdogs this season.
• When playing as a moneyline favorite with odds of -218 or shorter, Houston has gone 20-1 (95.2% win percentage).
• Duke has not entered a game this season with longer moneyline odds than +180.

Houston vs. Duke: 2023-24 Stats Comparison

Houston 2023-24 Key Players

Duke 2023-24 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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