Purdue vs. McNeese Prediction, Odds, Picks - NCAA Tournament Second Round

Updated Mar. 22, 2025 10:27 a.m. ET

Data Skrive

The No. 4 seed Purdue Boilermakers (23-11) take on the No. 12 seed McNeese Cowboys (28-6) with a Sweet 16 spot up for grabs on Saturday at Amica Mutual Pavilion.

NCAA BK

NCAA TOURNMENT - SECOND ROUND

Purdue Boilermakers PUR

FINAL

PUR -6.5 UNDER 140.5

The Boilermakers hit the court as 6.5-point favorites against the Cowboys. The game features an over/under of 142.5.

Keep reading to get everything you need to know before placing bets on the Purdue-McNeese clash.

Purdue vs. McNeese Game Information & Odds

When: Saturday, March 22, 2025 at 12:10 p.m. ET
Where: Amica Mutual Pavilion in Providence, Rhode Island
How to watch on TV: CBS
Live boxscore on FOX Sports

Boilermakers vs Cowboys Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Boilermakers	-6.5	-108	-112	142.5	-108	-112	-258	+210

Purdue vs. McNeese Prediction

Pick ATS: McNeese (+6.5)
Pick OU: Over (142.5)
Prediction: Purdue 75, McNeese 69

Learn more about the Purdue Boilermakers vs. the McNeese Cowboys game on FOX Sports!

Purdue vs. McNeese Betting Insights

Betting Line Implied Predictions

Per the spread and over/under, the implied score for the matchup is Boilermakers 74, Cowboys 68.
The Boilermakers have a 72.1% chance to collect the win in this matchup based on the moneyline's implied probability.
The Cowboys have a 32.3% implied probability to come out on top.

Key Spread Facts

Purdue has won 18 games against the spread this season, while failing to cover 15 times.
McNeese has covered 16 times in 32 games with a spread this year.
When playing as at least 6.5-point favorites this season, Purdue has an ATS record of 10-5.
McNeese has covered the spread three times this year (3-0 ATS) when playing as at least 6.5-point underdogs.

Key Total Facts

Boilermakers games have finished with more than 142.5 points 19 times so far this season.
Cowboys games have gone over 142.5 points on 12 occasions this season.
The total for this matchup is 142.5 points, 12.3 fewer than the combined scoring average of the two teams.

Key Moneyline Facts

Purdue has gone 20-5 in games when it was favored on the moneyline (winning 80%).
This season, McNeese has been the underdog three times and won one of those games.
When playing as a moneyline favorite with odds of -258 or shorter, Purdue has a record of 15-1 (93.8% win percentage).
McNeese has a record of 1-2 when it is set as the underdog by +210 or more by sportsbooks this season.

Purdue vs. McNeese: 2024-25 Stats Comparison

	Purdue	McNeese
Points Scored Per Game (Rank)	77.8 (78)	77 (90)
Points Allowed (Rank)	70.9 (145)	64.1 (15)
Rebounds (Rank)	8.4 (221)	11 (37)
3pt Made (Rank)	8.2 (119)	7.5 (194)
Assists (Rank)	15.7 (54)	14 (141)
Turnovers (Rank)	9.8 (47)	10.1 (76)

Purdue 2024-25 Key Players

Boilermakers Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Trey Kaufman-Renn	34	20.2	6.3	2.1	0.7	0.3	0.1
Braden Smith	34	16.2	4.6	8.6	2.2	0.2	2.4
Fletcher Loyer	34	13.6	2.1	1.7	0.5	0	2.1
Daniel Jacobsen	2	6.5	3.5	0	0	1.5	0
C.J. Cox	34	5.8	2.9	0.7	0.7	0	0.9

McNeese 2024-25 Key Players

Cowboys Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Javohn Garcia	27	13.3	3.3	1.9	1.5	0.4	1.2
Sincere Parker	33	12.1	2.5	0.5	0.8	0.2	1.1
Alyn Breed	3	11.7	5.7	1	1	0	0.7
Jovohn Garcia	8	10.9	4.1	2.4	1.4	1.3	0.6
Christian Shumate	34	10.6	6.4	0.9	0.6	1.3	0.5