Clemson vs. Duke Prediction, Odds, Picks - September 4

Updated Sep. 4, 2023 3:11 p.m. ET

Data Skrive

The No. 9 Clemson Tigers (0-0) are 12.5-point favorites when they visit the Duke Blue Devils (0-0) in an ACC matchup on Monday, September 4, 2023 at Brooks Field at Wallace Wade Stadium. The point total for the outing is set at 54.5.

Last season, the Tigers went 11-3 and lost the Orange Bowl. On offense, they averaged 33.2 points per game (30th in college football), and they allowed 20.9 per game (22nd in college football) defensively. The Blue Devils finished 9-4 last year and won the Military Bowl. They scored 32.8 points per game (32nd in college football) and allowed 22.1 (31st).

Clemson vs. Duke Game Information & Odds

When: Monday, September 4, 2023 at 8:00 PM ET
Location: Brooks Field at Wallace Wade Stadium in Wilmington, North Carolina
TV: ESPN
Live boxscore on FOX Sports

Clemson vs Duke Betting Information updated as of September 4, 2023, 2:45 PM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Clemson	-12.5 (-110)	-457	+346	54.5	-112	-108

Clemson vs. Duke Prediction

Pick ATS: Duke (+12.5)
Pick OU: Under (54.5)
Prediction: Clemson 29, Duke 25

Learn more about the Clemson Tigers vs. the Duke Blue Devils game on FOX Sports!

Clemson vs. Duke Betting Insights

Per the spread and over/under, the implied score for the game is Tigers 34, Blue Devils 21.
The Tigers have an 82.0% chance to win this game per the moneyline's implied probability. The Blue Devils have a 22.4% implied probability.
Clemson won seven games against the spread last season, failing to cover seven times.
Duke put together a 9-4-0 ATS record last year.

Clemson vs. Duke: 2022 Stats Comparison

	Clemson	Duke
Off. Points per Game (Rank)	33.2 (22)	32.8 (34)
Def. Points per Game (Rank)	20.9 (33)	22.1 (31)
Turnovers Allowed (Rank)	22 (107)	10 (6)
Turnovers Forced (Rank)	19 (51)	26 (7)

Clemson 2022 Key Players

Name	Position	Stats
D.J. Uiagalelei	QB	2,514 YDS (62.0%) / 22 TD / 7 INT 554 RUSH YDS / 7 RUSH TD / 39.6 RUSH YPG
Will Shipley	RB	1,182 YDS / 15 TD / 84.4 YPG / 5.6 YPC 38 REC / 242 REC YDS / 0 REC TD / 17.3 REC YPG
Antonio Williams	WR	55 REC / 598 YDS / 4 TD / 42.7 YPG
Phil Mafah	RB	515 YDS / 4 TD / 36.8 YPG / 5.3 YPC
Jeremiah Trotter Jr.	LB	78 TKL / 8.0 TFL / 6.0 SACK / 2 INT
Barrett Carter	LB	65 TKL / 7.0 TFL / 5.5 SACK / 2 INT
Trenton Simpson	LB	59 TKL / 2.0 TFL / 2.5 SACK
K.J. Henry	DE	45 TKL / 6.0 TFL / 3.5 SACK

Duke 2022 Key Players

Name	Position	Stats
Riley Leonard	QB	2,967 YDS (63.9%) / 20 TD / 6 INT 698 RUSH YDS / 13 RUSH TD / 53.7 RUSH YPG
Jordan Waters	RB	566 YDS / 8 TD / 43.5 YPG / 4.6 YPC
Jalon Calhoun	WR	62 REC / 873 YDS / 4 TD / 67.2 YPG
Jordan Moore	QB	0 YDS (%) / 0 TD / 0 INT
Darius Joiner	DB	56 TKL / 3.0 TFL / 4.0 SACK / 2 INT
Brandon Johnson	S	38 TKL / 5.0 TFL / 5.5 SACK / 2 INT
Shaka Heyward	LB	66 TKL / 2.0 TFL / 2.0 SACK / 2 INT
DeWayne Carter	DT	31 TKL / 7.0 TFL / 5.5 SACK