Clemson vs. Duke Prediction, Odds, Picks - September 4

Updated Sep. 4, 2023 3:11 p.m. ET

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The No. 9 Clemson Tigers (0-0) are 12.5-point favorites when they visit the Duke Blue Devils (0-0) in an ACC matchup on Monday, September 4, 2023 at Brooks Field at Wallace Wade Stadium. The point total for the outing is set at 54.5.

Last season, the Tigers went 11-3 and lost the Orange Bowl. On offense, they averaged 33.2 points per game (30th in college football), and they allowed 20.9 per game (22nd in college football) defensively. The Blue Devils finished 9-4 last year and won the Military Bowl. They scored 32.8 points per game (32nd in college football) and allowed 22.1 (31st).

Clemson vs. Duke Game Information & Odds

• When: Monday, September 4, 2023 at 8:00 PM ET
• Location: Brooks Field at Wallace Wade Stadium in Wilmington, North Carolina
• TV: ESPN
• Live boxscore on FOX Sports

Clemson vs. Duke Prediction

• Pick ATS: Duke (+12.5)
  
• Pick OU: Under (54.5)
  
• Prediction: Clemson 29, Duke 25

Learn more about the Clemson Tigers vs. the Duke Blue Devils game on FOX Sports!

Clemson vs. Duke Betting Insights

• Per the spread and over/under, the implied score for the game is Tigers 34, Blue Devils 21.
• The Tigers have an 82.0% chance to win this game per the moneyline's implied probability. The Blue Devils have a 22.4% implied probability.
• Clemson won seven games against the spread last season, failing to cover seven times.
• Duke put together a 9-4-0 ATS record last year.

Clemson vs. Duke: 2022 Stats Comparison

Clemson 2022 Key Players

Duke 2022 Key Players

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