Clemson vs. South Carolina Prediction, Odds, Picks - November 25

Updated Nov. 25, 2023 3:05 p.m. ET

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The 2023 edition of the Palmetto Bowl on Saturday, November 25 will see the Clemson Tigers (7-4) visit the South Carolina Gamecocks (5-6) at Williams-Brice Stadium. The Tigers are favored by 7.5 points in the outing. This game has an over/under of 48 points.

The Tigers' most recent contest was versus the North Carolina Tar Heels, and they won by a score of 31-20. The Gamecocks' last game was versus the Kentucky Wildcats, and they won by a score of 17-14.

Clemson vs. South Carolina Game Information & Odds

• When: Saturday, November 25, 2023 at 7:30 PM ET
• Location: Williams-Brice Stadium in Columbia, South Carolina
• TV: SEC Network
• Live boxscore on FOX Sports

Clemson vs. South Carolina Prediction

• Pick ATS: South Carolina (+7.5)
  
• Pick OU: Over (48)
  
• Prediction: Clemson 28, South Carolina 23

Learn more about the Clemson Tigers vs. the South Carolina Gamecocks game on FOX Sports!

Clemson vs. South Carolina Betting Insights

• Per the spread and over/under, the implied score for the game is Tigers 28, Gamecocks 20.
• The Tigers have a 75.4% chance to claim victory in this meeting based on the moneyline's implied probability. The Gamecocks have a 28.8% implied probability.
• Clemson has covered five times in 10 games with a spread this season.
• South Carolina has put together a 6-5-0 ATS record so far this season.

Clemson vs. South Carolina: Head-to-Head

• The last two times South Carolina and Clemson have matched up, the two teams share a split 1-1 record.
• The Tigers and the Gamecocks have matched up evenly over their last two head-to-head meetings, holding a split 1-1 record against the spread. In those two head-to-head matchups, the two squads have eclipsed the over on the total on one occasion.
• In their last two head-to-head matchups, Clemson has tallied 60 points against South Carolina, while giving up only 31 points.

Clemson vs. South Carolina: 2023 Stats Comparison

Clemson 2023 Key Players

South Carolina 2023 Key Players

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