College Football Top 25 Week 5 Predictions, Betting Odds & TV Schedule

Updated Sep. 30, 2023 8:27 p.m. ET

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The Week 5 college football slate includes 16 games with a ranked team in play. Among those contests is the No. 24 Kansas Jayhawks playing the No. 3 Texas Longhorns.

Looking for an edge in college football? We break down the betting odds for each of the important games below.

Week 5 Betting Lines & Game Info

No. 19 Oregon State Beavers vs. No. 10 Utah Utes

Odds & Prediction

• Spread: Beavers (-4)
• Moneyline: Beavers -180, Utes +150
• Total: 43 points
• Prediction: Oregon State 22, Utah 20

How to Watch

• Game Date: Friday, September 29
• Game Time: 9:00 PM ET
• TV Channel: Watch Online: Fox Sports 1
• Location: Corvallis, Oregon

Kentucky Wildcats vs. No. 22 Florida Gators

Odds & Prediction

• Spread: Wildcats (-1.5)
• Moneyline: Wildcats -122, Gators +102
• Total: 44 points
• Prediction: Florida 26, Kentucky 20

How to Watch

• Game Date: Saturday, September 30
• Game Time: 12:00 PM ET
• TV Channel: ESPN
• Location: Lexington, Kentucky

Northwestern Wildcats vs. No. 6 Penn State Nittany Lions

Odds & Prediction

• Spread: Nittany Lions (-27)
• Moneyline: Nittany Lions -4000, Wildcats +1600
• Total: 48 points
• Prediction: Penn State 36, Northwestern 11

How to Watch

• Game Date: Saturday, September 30
• Game Time: 12:00 PM ET
• TV Channel: BTN
• Location: Evanston, Illinois

Colorado Buffaloes vs. No. 8 USC Trojans

Odds & Prediction

• Spread: Trojans (-22)
• Moneyline: Trojans -1650, Buffaloes +950
• Total: 74 points
• Prediction: Colorado 36, USC 35

How to Watch

• Game Date: Saturday, September 30
• Game Time: 12:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Boulder, Colorado

Auburn Tigers vs. No. 1 Georgia Bulldogs

Odds & Prediction

• Spread: Bulldogs (-14)
• Moneyline: Bulldogs -600, Tigers +440
• Total: 45 points
• Prediction: Auburn 34, Georgia 14

How to Watch

• Game Date: Saturday, September 30
• Game Time: 3:30 PM ET
• TV Channel: CBS
• Location: Auburn, Alabama

Nebraska Cornhuskers vs. No. 2 Michigan Wolverines

Odds & Prediction

• Spread: Wolverines (-17.5)
• Moneyline: Wolverines -950, Cornhuskers +625
• Total: 39.5 points
• Prediction: Michigan 28, Nebraska 11

How to Watch

• Game Date: Saturday, September 30
• Game Time: 3:30 PM ET
• TV Channel: Watch Online: FOX
• Location: Lincoln, Nebraska

No. 3 Texas Longhorns vs. No. 24 Kansas Jayhawks

Odds & Prediction

• Spread: Longhorns (-16)
• Moneyline: Longhorns -750, Jayhawks +525
• Total: 60.5 points
• Prediction: Texas 39, Kansas 14

How to Watch

• Game Date: Saturday, September 30
• Game Time: 3:30 PM ET
• TV Channel: ABC
• Location: Austin, Texas

Vanderbilt Commodores vs. No. 23 Missouri Tigers

Odds & Prediction

• Spread: Tigers (-14)
• Moneyline: Tigers -575, Commodores +425
• Total: 54.5 points
• Prediction: Missouri 42, Vanderbilt 18

How to Watch

• Game Date: Saturday, September 30
• Game Time: 4:00 PM ET
• TV Channel: SEC Network
• Location: Nashville, Tennessee

No. 20 Ole Miss Rebels vs. No. 13 LSU Tigers

Odds & Prediction

• Spread: Tigers (-2.5)
• Moneyline: Tigers -142, Rebels +120
• Total: 67 points
• Prediction: Ole Miss 40, LSU 18

How to Watch

• Game Date: Saturday, September 30
• Game Time: 6:00 PM ET
• TV Channel: ESPN
• Location: Oxford, Mississippi

Stanford Cardinal vs. No. 9 Oregon Ducks

Odds & Prediction

• Spread: Ducks (-27)
• Moneyline: Ducks -4000, Cardinal +1600
• Total: 60 points
• Prediction: Oregon 45, Stanford 13

How to Watch

• Game Date: Saturday, September 30
• Game Time: 6:30 PM ET
• TV Channel: Pac-12 Network
• Location: Stanford, California

No. 14 Oklahoma Sooners vs. Iowa State Cyclones

Odds & Prediction

• Spread: Sooners (-20)
• Moneyline: Sooners -1200, Cyclones +750
• Total: 49 points
• Prediction: Oklahoma 41, Iowa State 5

How to Watch

• Game Date: Saturday, September 30
• Game Time: 7:00 PM ET
• TV Channel: Watch Online: Fox Sports 1
• Location: Norman, Oklahoma

No. 17 Duke Blue Devils vs. No. 11 Notre Dame Fighting Irish

Odds & Prediction

• Spread: Fighting Irish (-5.5)
• Moneyline: Fighting Irish -205, Blue Devils +170
• Total: 52.5 points
• Prediction: Duke 25, Notre Dame 23

How to Watch

• Game Date: Saturday, September 30
• Game Time: 7:30 PM ET
• TV Channel: ABC
• Location: Wilmington, North Carolina

No. 21 Tennessee Volunteers vs. South Carolina Gamecocks

Odds & Prediction

• Spread: Volunteers (-12.5)
• Moneyline: Volunteers -470, Gamecocks +360
• Total: 60 points
• Prediction: Tennessee 39, South Carolina 14

How to Watch

• Game Date: Saturday, September 30
• Game Time: 7:30 PM ET
• TV Channel: SEC Network
• Location: Knoxville, Tennessee

Mississippi State Bulldogs vs. No. 12 Alabama Crimson Tide

Odds & Prediction

• Spread: Crimson Tide (-14.5)
• Moneyline: Crimson Tide -700, Bulldogs +500
• Total: 46 points
• Prediction: Alabama 44, Mississippi State 7

How to Watch

• Game Date: Saturday, September 30
• Game Time: 9:00 PM ET
• TV Channel: ESPN
• Location: Starkville, Mississippi

Arizona Wildcats vs. No. 7 Washington Huskies

Odds & Prediction

• Spread: Huskies (-20)
• Moneyline: Huskies -1200, Wildcats +750
• Total: 65 points
• Prediction: Washington 46, Arizona 11

How to Watch

• Game Date: Saturday, September 30
• Game Time: 10:00 PM ET
• TV Channel: Pac-12 Network
• Location: Tucson, Arizona

No. 25 Fresno State Bulldogs vs. Nevada Wolf Pack

Odds & Prediction

• Spread: Bulldogs (-25.5)
• Moneyline: Bulldogs -3200, Wolf Pack +1400
• Total: 50.5 points
• Prediction: Fresno State 41, Nevada 19

How to Watch

• Game Date: Saturday, September 30
• Game Time: 10:30 PM ET
• TV Channel: Watch Online: Fox Sports 1
• Location: Fresno, California

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