College Football Top 25 Week 6 2024 Predictions, Betting Odds & TV Schedule
Top-25 teams will be in action in 17 games on the Week 6 college football schedule. That includes the No. 1 Alabama Crimson Tide squaring off against the Vanderbilt Commodores at FirstBank Stadium.
To pick up an edge prior to Week 6 in college football, see our odds breakdown below.
Check out the full college football schedule on FOX Sports! Or visit FOX Sports' college football hub for everything you need to make the most of this season's action.
Week 6 Betting Lines & Game Info
No. 6 Oregon Ducks vs. Michigan State Spartans
Odds & Prediction
- Spread: Ducks (-23.5)
- Moneyline: Ducks -2778, Spartans +1300
- Total: 52 points
- Prediction: Oregon 36, Michigan State 15
How to Watch
- Game Date: Friday, Oct. 4
- Game Time: 9:00 PM ET
- TV Channel: Watch Online: FOX
- Location: Eugene, Oregon
- Box Score
No. 25 UNLV Rebels vs. Syracuse Orange
Odds & Prediction
- Spread: Rebels (-5)
- Moneyline: Rebels -198, Orange +164
- Total: 58.5 points
- Prediction: UNLV 35, Syracuse 18
How to Watch
- Game Date: Friday, Oct. 4
- Game Time: 9:00 PM ET
- TV Channel: Watch Online: Fox Sports 1
- Location: Paradise, Nevada
- Box Score
No. 7 Penn State Nittany Lions vs. UCLA Bruins
Odds & Prediction
- Spread: Nittany Lions (-28)
- Moneyline: Nittany Lions -6667, Bruins +2000
- Total: 44.5 points
- Prediction: Penn State 33, UCLA 14
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 12:00 PM ET
- TV Channel: Watch Online: FOX
- Location: University Park, Pennsylvania
- Box Score
No. 22 Louisville Cardinals vs. SMU Mustangs
Odds & Prediction
- Spread: Cardinals (-7)
- Moneyline: Cardinals -250, Mustangs +205
- Total: 58 points
- Prediction: SMU 30, Louisville 29
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 12:00 PM ET
- TV Channel: ESPN
- Location: Louisville, Kentucky
- Box Score
Texas A&M Aggies vs. No. 9 Missouri Tigers
Odds & Prediction
- Spread: Aggies (-1.5)
- Moneyline: Aggies -120, Tigers +100
- Total: 49.5 points
- Prediction: Missouri 24, Texas A&M 21
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 12:00 PM ET
- TV Channel: ABC
- Location: College Station, Texas
- Box Score
No. 5 Georgia Bulldogs vs. Auburn Tigers
Odds & Prediction
- Spread: Bulldogs (-23.5)
- Moneyline: Bulldogs -2381, Tigers +1200
- Total: 52.5 points
- Prediction: Georgia 41, Auburn 5
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 3:30 PM ET
- TV Channel: ABC
- Location: Athens, Georgia
- Box Score
South Carolina Gamecocks vs. No. 12 Ole Miss Rebels
Odds & Prediction
- Spread: Rebels (-9.5)
- Moneyline: Rebels -325, Gamecocks +260
- Total: 51.5 points
- Prediction: South Carolina 26, Ole Miss 25
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 3:30 PM ET
- TV Channel: ESPN
- Location: Columbia, South Carolina
- Box Score
No. 3 Ohio State Buckeyes vs. Iowa Hawkeyes
Odds & Prediction
- Spread: Buckeyes (-20.5)
- Moneyline: Buckeyes -1639, Hawkeyes +950
- Total: 44.5 points
- Prediction: Ohio State 35, Iowa 16
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 3:30 PM ET
- TV Channel: CBS
- Location: Columbus, Ohio
- Box Score
Northwestern Wildcats vs. No. 23 Indiana Hoosiers
Odds & Prediction
- Spread: Hoosiers (-13)
- Moneyline: Hoosiers -575, Wildcats +425
- Total: 42.5 points
- Prediction: Indiana 34, Northwestern 11
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 3:30 PM ET
- TV Channel: BTN
- Location: Evanston, Illinois
- Box Score
Vanderbilt Commodores vs. No. 1 Alabama Crimson Tide
Odds & Prediction
- Spread: Crimson Tide (-24)
- Moneyline: Crimson Tide -2381, Commodores +1200
- Total: 55 points
- Prediction: Alabama 43, Vanderbilt 19
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 4:15 PM ET
- TV Channel: SEC Network
- Location: Nashville, Tennessee
- Box Score
No. 21 Boise State Broncos vs. Utah State Aggies
Odds & Prediction
- Spread: Broncos (-26.5)
- Moneyline: Broncos -3226, Aggies +1400
- Total: 66 points
- Prediction: Boise State 59, Utah State 12
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 7:00 PM ET
- TV Channel: Watch Online: Fox Sports 2
- Location: Boise, Idaho
- Box Score
Florida State Seminoles vs. No. 15 Clemson Tigers
Odds & Prediction
- Spread: Tigers (-14)
- Moneyline: Tigers -676, Seminoles +490
- Total: 47 points
- Prediction: Clemson 34, Florida State 20
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 7:00 PM ET
- TV Channel: ESPN
- Location: Tallahassee, Florida
- Box Score
No. 16 Iowa State Cyclones vs. Baylor Bears
Odds & Prediction
- Spread: Cyclones (-13)
- Moneyline: Cyclones -575, Bears +425
- Total: 46.5 points
- Prediction: Iowa State 31, Baylor 14
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 7:30 PM ET
- TV Channel: Watch Online: FOX
- Location: Ames, Iowa
- Box Score
Minnesota Golden Gophers vs. No. 11 USC Trojans
Odds & Prediction
- Spread: Trojans (-8.5)
- Moneyline: Trojans -345, Golden Gophers +275
- Total: 52 points
- Prediction: USC 27, Minnesota 19
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 7:30 PM ET
- TV Channel: BTN
- Location: Minneapolis, Minnesota
- Box Score
Washington Huskies vs. No. 10 Michigan Wolverines
Odds & Prediction
- Spread: Huskies (-2.5)
- Moneyline: Huskies -135, Wolverines +114
- Total: 41 points
- Prediction: Washington 24, Michigan 18
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 7:30 PM ET
- TV Channel: NBC
- Location: Seattle, Washington
- Box Score
Arkansas Razorbacks vs. No. 4 Tennessee Volunteers
Odds & Prediction
- Spread: Volunteers (-14)
- Moneyline: Volunteers -599, Razorbacks +440
- Total: 60 points
- Prediction: Tennessee 38, Arkansas 17
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 7:30 PM ET
- TV Channel: ABC
- Location: Fayetteville, Arkansas
- Box Score
California Golden Bears vs. No. 8 Miami (FL) Hurricanes
Odds & Prediction
- Spread: Hurricanes (-12.5)
- Moneyline: Hurricanes -500, Golden Bears +380
- Total: 55 points
- Prediction: Miami (FL) 37, Cal 11
How to Watch
- Game Date: Saturday, Oct. 5
- Game Time: 10:30 PM ET
- TV Channel: ESPN
- Location: Berkeley, California
- Box Score
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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