Missouri vs. South Carolina Prediction, Odds, Picks - October 21

Updated Oct. 21, 2023 3:05 p.m. ET

Data Skrive

The No. 20 Missouri Tigers (6-1), who have college football's 18th-ranked passing offense, take on the South Carolina Gamecocks (2-4) and their 13th-ranked passing attack on Saturday, October 21, 2023. The Tigers are 7.5-point favorites. The over/under is set at 57.5 for the contest.

The Tigers' last game was against the Kentucky Wildcats, and they won by a score of 38-21. In their most recent game, the Gamecocks lost versus the Florida Gators, 41-39.

Missouri vs. South Carolina Game Information & Odds

When: Saturday, October 21, 2023 at 3:30 PM ET
Location: Faurot Field at Memorial Stadium in Columbia, Missouri
TV: SEC Network
Live boxscore on FOX Sports

Missouri vs South Carolina Betting Information updated as of October 21, 2023, 2:46 PM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Missouri	-7.5 (-106)	-311	+245	57.5	-110	-110

Missouri vs. South Carolina Prediction

Pick ATS: Missouri (-7.5)
Pick OU: Over (57.5)
Prediction: Missouri 37, South Carolina 22

Learn more about the Missouri Tigers vs. the South Carolina Gamecocks game on FOX Sports!

Missouri vs. South Carolina Betting Insights

Based on the spread and over/under, the implied score for the game is Tigers 32, Gamecocks 25.
The Tigers have a 75.7% chance to collect the win in this game based on the moneyline's implied probability. The Gamecocks hold a 29.0% implied probability.
Missouri has won four games against the spread this season, while failing to cover twice.
South Carolina has covered three times in six matchups with a spread this season.

Missouri vs. South Carolina: Head-to-Head

Over their last two meetings, Missouri has tallied two wins against South Carolina.
The last two times the Tigers have gone up against the Gamecocks, they have posted a 2-0 record against the spread. The scoring has gone over the total on one occasion.
South Carolina has been outscored by 16 points in its last two tilts versus Missouri.

Missouri vs. South Carolina: 2023 Stats Comparison

	Missouri	South Carolina
Off. Points per Game (Rank)	33.9 (25)	29.0 (80)
Def. Points per Game (Rank)	24.9 (77)	31.3 (89)
Turnovers Allowed (Rank)	6 (22)	7 (34)
Turnovers Forced (Rank)	7 (96)	7 (96)

Missouri 2023 Key Players

Name	Position	Stats
Brady Cook	QB	2,038 YDS (71.0%) / 14 TD / 3 INT 86 RUSH YDS / 4 RUSH TD / 12.3 RUSH YPG
Luther Burden III	WR	56 REC / 808 YDS / 5 TD / 115.4 YPG
Cody Schrader	RB	648 YDS / 7 TD / 92.6 YPG / 5.7 YPC
Theo Wease	WR	34 REC / 400 YDS / 5 TD / 57.1 YPG
Johnny Walker Jr.	DL	25 TKL / 4.0 TFL / 3.5 SACK
Ty'Ron Hopper	LB	37 TKL / 4.0 TFL / 1.0 SACK
Kris Abrams-Draine	DB	25 TKL / 0.0 TFL / 4 INT / 4 PD
Darius Robinson	DL	15 TKL / 3.0 TFL / 3.5 SACK

South Carolina 2023 Key Players

Name	Position	Stats
Spencer Rattler	QB	1,724 YDS (73.6%) / 11 TD / 4 INT 129 RUSH YDS / 2 RUSH TD / 21.5 RUSH YPG
Xavier Legette	WR	37 REC / 716 YDS / 3 TD / 119.3 YPG
Mario Anderson	RB	328 YDS / 2 TD / 54.7 YPG / 5.1 YPC 5 REC / 41 REC YDS / 1 REC TD / 6.8 REC YPG
Dakereon Joyner	RB	106 YDS / 4 TD / 17.7 YPG / 2.5 YPC 15 REC / 86 REC YDS / 0 REC TD / 14.3 REC YPG
Debo Williams	LB	41 TKL / 5.0 TFL / 1.0 SACK
DQ Smith	DB	42 TKL / 0.0 TFL / 0.5 SACK / 1 INT
T.J. Sanders	DT	17 TKL / 6.0 TFL / 4.5 SACK
Jalon Kilgore	DB	39 TKL / 0.0 TFL / 1 INT / 1 PD