North Carolina vs. Virginia Prediction, Odds, Picks - October 21

Updated Oct. 21, 2023 3:05 p.m. ET

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Oddsmakers heavily favor the No. 10 North Carolina Tar Heels (6-0) when they host the Virginia Cavaliers (1-5) on Saturday, October 21, 2023 in a matchup between ACC foes at Kenan Memorial Stadium. North Carolina is favored by 23.5 points. The over/under is 58 for this matchup.

The Tar Heels won against the Miami Hurricanes in their last game, 41-31. The Cavaliers beat the William & Mary Tribe, 27-13, in their most recent game.

North Carolina vs. Virginia Game Information & Odds

• When: Saturday, October 21, 2023 at 6:30 PM ET
• Location: Kenan Memorial Stadium in Chapel Hill, North Carolina
• TV: The CW
• Live boxscore on FOX Sports

North Carolina vs. Virginia Prediction

• Pick ATS: North Carolina (-23.5)
  
• Pick OU: Under (58)
  
• Prediction: North Carolina 42, Virginia 16

Learn more about the North Carolina Tar Heels vs. the Virginia Cavaliers game on FOX Sports!

North Carolina vs. Virginia Betting Insights

• Per the spread and over/under, the implied score for the matchup is Tar Heels 41, Cavaliers 17.
• The Tar Heels have a 96.4% chance to claim victory in this contest per the moneyline's implied probability. The Cavaliers hold a 7.9% implied probability.
• North Carolina has covered five times in six games with a spread this season.
• Virginia has covered four times in six chances against the spread this year.

North Carolina vs. Virginia: Head-to-Head

• Over their last two meetings, North Carolina has tallied two wins versus Virginia.
• In their most recent two meetings, each team has covered one time with those games going over the total on one occasion.
• In their last two head-to-head matchups, North Carolina has racked up 90 points against Virginia, while giving up only 67 points.

North Carolina vs. Virginia: 2023 Stats Comparison

North Carolina 2023 Key Players

Virginia 2023 Key Players

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CFB - Virginia Cavaliers vs. North Carolina Tar Heels - 10/21/2023

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