Notre Dame vs. Louisville Prediction, Odds, Picks - September 28, 2024

Notre Dame vs. Louisville Prediction, Odds, Picks - September 28, 2024

Updated Sep. 28, 2024 3:11 p.m. ET
Data Skrive

The No. 16 Notre Dame Fighting Irish (3-1) are less than a touchdown favorite (-6.5) on Saturday, September 28, 2024 against the No. 15 Louisville Cardinals (3-0). The point total is 45.5.

The Fighting Irish's last game was against the Miami (OH) RedHawks, and they won by a score of 28-3. In their last game, the Cardinals won versus the Georgia Tech Yellow Jackets, 31-19.

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Notre Dame vs. Louisville Game Information & Odds

  • When: Saturday, September 28, 2024 at 3:30 p.m. ET
  • Location: Notre Dame Stadium in South Bend, Indiana
  • TV: Peacock
  • Live Box Score on FOX Sports

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Notre Dame vs Louisville Betting Information updated as of September 28, 2024, 2:47 p.m. ET.
Favorite Spread (Odds) Favorite Moneyline Underdog Moneyline Total Over Moneyline Under Moneyline
Notre Dame -6.5 (-112) -243 +196 45.5 -109 -111

Notre Dame vs. Louisville Prediction

  • Pick ATS: Louisville (+6.5)
  • Pick OU: Over (45.5)
  • Prediction: Notre Dame 26, Louisville 24

Predictions are made by the Data Skrive betting model.

Learn more about the Notre Dame Fighting Irish vs. the Louisville Cardinals game on FOX Sports!

Read More About This Game

Notre Dame vs. Louisville Betting Insights

  • Based on the spread and over/under, the implied score for the game is Fighting Irish 26, Cardinals 20.
  • The Fighting Irish have a 70.8% chance to collect the win in this meeting based on the moneyline's implied probability. The Cardinals hold a 33.8% implied probability.
  • Notre Dame has a record of 2-2-0 against the spread this season.
  • Louisville has won two games against the spread this year.

Notre Dame vs. Louisville: 2024 Stats Comparison

Notre Dame Louisville
Off. Points per Game (Rank) 32.8 (41) 47.3 (28)
Def. Points per Game (Rank) 9.8 (10) 11 (8)
Turnovers Allowed (Rank) 4 (51) 0 (1)
Turnovers Forced (Rank) 6 (41) 4 (74)

Notre Dame 2024 Key Players

Name Position Stats
Riley Leonard QB 587 YDS (63.1%) / 1 TD / 2 INT
322 RUSH YDS / 6 RUSH TD / 80.5 RUSH YPG
Jeremiyah Love RB 339 YDS / 4 TD / 84.8 YPG / 7.4 YPC
Jadarian Price RB 193 YDS / 2 TD / 48.3 YPG / 7.4 YPC
Beaux Collins WR 16 REC / 176 YDS / 1 TD / 44 YPG
Boubacar Traore DL 10 TKL / 4 TFL / 3 SACK / 1 INT
Xavier Watts DB 13 TKL / 0 TFL / 1 INT / 1 PD
Drayk Bowen LB 13 TKL / 1 TFL / 1 SACK
Jack Kiser LB 20 TKL / 0 TFL

Louisville 2024 Key Players

Name Position Stats
Tyler Shough QB 850 YDS (68.4%) / 8 TD / 0 INT
Ja'Corey Brooks WR 17 REC / 297 YDS / 2 TD / 99 YPG
Chris Bell WR 6 REC / 167 YDS / 2 TD / 55.7 YPG
Keyjuan Brown RB 126 YDS / 2 TD / 42 YPG / 6.6 YPC
3 REC / 34 REC YDS / 0 REC TD / 11.3 REC YPG
Tramel Logan DL 3 TKL / 2 TFL / 3 SACK
Jared Dawson DL 6 TKL / 3 TFL / 2 SACK
Tamarion McDonald DB 4 TKL / 3 TFL / 2 SACK
Quincy Riley DB 2 TKL / 0 TFL / 1 INT / 1 PD

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Notre Dame Fighting Irish
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