Notre Dame vs. USC Prediction, Odds, Picks - October 14

Updated Oct. 14, 2023 3:05 p.m. ET

Data Skrive

The No. 10 USC Trojans (6-0) and the third-ranked pass offense will take the field against the No. 21 Notre Dame Fighting Irish (5-2) and the third-ranked passing defense on Saturday, October 14, 2023. The Fighting Irish are favored by 3 points in the contest. The total is 60.5 points for this game.

Last time around, the Fighting Irish fell to the Louisville Cardinals, with 33-20 being the final score. The Trojans won versus the Arizona Wildcats in their most recent game, 43-41.

Notre Dame vs. USC Game Information & Odds

When: Saturday, October 14, 2023 at 7:30 PM ET
Location: Notre Dame Stadium in South Bend, Indiana
TV: NBC
Live boxscore on FOX Sports

Notre Dame vs USC Betting Information updated as of October 14, 2023, 2:46 PM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Notre Dame	-3 (-105)	-143	+121	60.5	-110	-110

Notre Dame vs. USC Prediction

Pick ATS: Notre Dame (-3)
Pick OU: Over (60.5)
Prediction: Notre Dame 36, USC 28

Learn more about the Notre Dame Fighting Irish vs. the USC Trojans game on FOX Sports!

Notre Dame vs. USC Betting Insights

Per the spread and over/under, the implied score for the tilt is Fighting Irish 32, Trojans 29.
The Fighting Irish have a 58.8% chance to win this contest based on the moneyline's implied probability. The Trojans hold a 45.2% implied probability.
Notre Dame has covered four times in seven games with a spread this season.
USC has won two games against the spread this season.

Notre Dame vs. USC: Head-to-Head

Notre Dame and USC have been matched up evenly over their last two games, sharing the same 1-1 record.
In their last two meetings, each team has covered one time with those games eclipsing the total on one occasion.
In their last two head-to-head matchups, Notre Dame has scored 58 points versus USC, while surrendering only 54 points.

Notre Dame vs. USC: 2023 Stats Comparison

	Notre Dame	USC
Off. Points per Game (Rank)	34.1 (11)	51.8 (1)
Def. Points per Game (Rank)	15.9 (33)	27.0 (83)
Turnovers Allowed (Rank)	7 (47)	4 (10)
Turnovers Forced (Rank)	8 (58)	8 (58)

Notre Dame 2023 Key Players

Name	Position	Stats
Sam Hartman	QB	1,712 YDS (64.5%) / 16 TD / 3 INT 2 RUSH YDS / 2 RUSH TD / 0.3 RUSH YPG
Audric Estime	RB	692 YDS / 7 TD / 98.9 YPG / 6.6 YPC 10 REC / 89 REC YDS / 0 REC TD / 12.7 REC YPG
Chris Tyree	WR	14 REC / 293 YDS / 2 TD / 41.9 YPG
Mitchell Evans	TE	22 REC / 343 YDS / 1 TD / 49.0 YPG
Howard Cross III	DL	40 TKL / 2.0 TFL / 1.0 SACK
JD Bertrand	LB	40 TKL / 3.0 TFL / 1.0 SACK
Jack Kiser	LB	32 TKL / 0.0 TFL / 1.0 SACK
Marist Liufau	LB	29 TKL / 1.0 TFL / 0.5 SACK

USC 2023 Key Players

Name	Position	Stats
Caleb Williams	QB	1,822 YDS (71.3%) / 22 TD / 1 INT 124 RUSH YDS / 6 RUSH TD / 20.7 RUSH YPG
Brenden Rice	WR	21 REC / 434 YDS / 7 TD / 72.3 YPG
MarShawn Lloyd	RB	519 YDS / 4 TD / 86.5 YPG / 7.7 YPC 5 REC / 79 REC YDS / 0 REC TD / 13.2 REC YPG
Tahj Washington	WR	21 REC / 456 YDS / 5 TD / 76.0 YPG
Jamil Muhammad	DE	16 TKL / 7.0 TFL / 6.0 SACK
Solomon Byrd	DE	15 TKL / 2.0 TFL / 4.5 SACK
Jaylin Smith	S	35 TKL / 4.0 TFL
Romello Height	DE	8 TKL / 4.0 TFL / 3.0 SACK