Ohio State vs. Indiana Prediction, Odds, Picks - November 23, 2024

Updated Nov. 23, 2024 9:05 a.m. ET

Data Skrive

The No. 2 Ohio State Buckeyes (9-1) are 10.5-point favorites at home at Ohio Stadium against the No. 5 Indiana Hoosiers (10-0) on Saturday, November 23, 2024. Both teams have strong pass defenses, with the Buckeyes sixth against the pass in the nation, and the Hoosiers 21st defending the passing game. This game has an over/under of 52.5 points.

The Buckeyes' most recent game was versus the Northwestern Wildcats, and they won by a score of 31-7. The Hoosiers won versus the Michigan Wolverines in their most recent game, 20-15.

Keep up with college football all season on FOX Sports.

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Check out this Big Noon Kickoff, College Football 25 simulation of the Indiana Hoosiers and the Ohio State Buckeyes.

Ohio State vs. Indiana Game Information & Odds

When: Saturday, November 23, 2024 at 12 p.m. ET
Location: Ohio Stadium in Columbus, Ohio
TV: FOX
Live Box Score on FOX Sports

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Ohio State vs Indiana Betting Information updated as of November 23, 2024, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Ohio State	-10.5 (-110)	-417	+318	52.5	-111	-109

Ohio State vs. Indiana Prediction

Pick ATS: Indiana (+10.5)
Pick OU: Under (52.5)
Prediction: Ohio State 29, Indiana 22

Predictions are made by the Data Skrive betting model.

Learn more about the Ohio State Buckeyes vs. the Indiana Hoosiers game on FOX Sports!

Ohio State vs. Indiana Betting Insights

Based on the spread and over/under, the implied score for the matchup is Buckeyes 32, Hoosiers 21.
The Buckeyes have an 80.7% chance to win this contest per the moneyline's implied probability. The Hoosiers have a 23.9% implied probability.
Ohio State has won five games against the spread this season, while failing to cover five times.
Indiana is 8-2-0 ATS this year.

Ohio State vs. Indiana: Head-to-Head

In their past three head-to-head meetings, Ohio State has taken down Indiana three times.
The last three times the Buckeyes have gone up against the Hoosiers, they have a 2-1 record against the spread. The scoring has gone over the total on two occasions.
Over their last three head-to-head matchups, Ohio State has put up 133 points, while Indiana has posted 24.

Ohio State vs. Indiana: 2024 Stats Comparison

	Ohio State	Indiana
Off. Points per Game (Rank)	37.8 (13)	43.9 (3)
Def. Points per Game (Rank)	10.3 (2)	13.8 (7)
Turnovers Allowed (Rank)	9 (22)	7 (6)
Turnovers Forced (Rank)	14 (55)	17 (31)

Ohio State 2024 Key Players

Name	Position	Stats
Will Howard	QB	2,484 YDS (72.9%) / 24 TD / 5 INT 128 RUSH YDS / 6 RUSH TD / 12.8 RUSH YPG
Jeremiah Smith	WR	49 REC / 865 YDS / 9 TD / 86.5 YPG
Quinshon Judkins	RB	723 YDS / 8 TD / 72.3 YPG / 6 YPC 13 REC / 102 REC YDS / 1 REC TD / 10.2 REC YPG
Emeka Egbuka	WR	49 REC / 612 YDS / 8 TD / 61.2 YPG
Sonny Styles	DB	46 TKL / 6 TFL / 4 SACK
Cody Simon	LB	42 TKL / 5 TFL / 2.5 SACK
J.T. Tuimoloau	DL	23 TKL / 6 TFL / 5 SACK
Lathan Ransom	DB	34 TKL / 5 TFL / 1 INT / 1 PD

Indiana 2024 Key Players

Name	Position	Stats
Kurtis Rourke	QB	2,410 YDS (71.8%) / 21 TD / 4 INT 17 RUSH YDS / 2 RUSH TD / 1.7 RUSH YPG
Justice Ellison	RB	686 YDS / 9 TD / 68.6 YPG / 5.7 YPC
Ty Son Lawton	RB	508 YDS / 9 TD / 50.8 YPG / 4.8 YPC 8 REC / 101 REC YDS / 0 REC TD / 11.2 REC YPG
Elijah Sarratt	WR	38 REC / 685 YDS / 6 TD / 68.5 YPG
Mikail Kamara	DL	34 TKL / 10 TFL / 8.5 SACK
Aiden Fisher	LB	84 TKL / 2 TFL / 1.5 SACK
Shawn Asbury II	DB	45 TKL / 3 TFL / 1.5 SACK / 1 INT
D'Angelo Ponds	DB	40 TKL / 2 TFL / 2 INT / 5 PD