Ohio State vs. Michigan State Prediction, Odds, Picks - September 28, 2024

Updated Sep. 28, 2024 3:10 p.m. ET

Data Skrive

Oddsmakers heavily favor the No. 3 Ohio State Buckeyes (3-0) when they visit the Michigan State Spartans (3-1) on Saturday, September 28, 2024 in a matchup between Big Ten rivals at Spartan Stadium. Ohio State is favored by 23.5 points. The over/under is 48 for this matchup.

Last time around, the Buckeyes defeated the Marshall Thundering Herd, with 49-14 being the final score. The Spartans lost to the Boston College Eagles, 23-19, in their most recent game.

Keep up with college football all season on FOX Sports.

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Ohio State vs. Michigan State Game Information & Odds

When: Saturday, September 28, 2024 at 7:30 p.m. ET
Location: Spartan Stadium in East Lansing, Michigan
TV: Peacock
Live Box Score on FOX Sports

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Ohio State vs Michigan State Betting Information updated as of September 28, 2024, 2:48 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Ohio State	-23.5 (-111)	-3030	+1243	48	-109	-111

Ohio State vs. Michigan State Prediction

Pick ATS: Michigan State (+23.5)
Pick OU: Over (48)
Prediction: Michigan State 25, Ohio State 24

Predictions are made by the Data Skrive betting model.

Learn more about the Ohio State Buckeyes vs. the Michigan State Spartans game on FOX Sports!

Ohio State vs. Michigan State Betting Insights

Per the spread and over/under, the implied score for the tilt is Buckeyes 36, Spartans 12.
The Buckeyes have a 96.8% chance to win this contest per the moneyline's implied probability. The Spartans hold a 7.4% implied probability.
Ohio State has a record of 1-2-0 against the spread this season.
Michigan State has a record of 2-2-0 against the spread this season.

Ohio State vs. Michigan State: Head-to-Head

Over their last three meetings, Ohio State has collected three wins versus Michigan State.
The Buckeyes have a 3-0 record ATS in those games, while the two teams have gone over the total on one occasion.
Michigan State has been outpaced by 113 points in its last three tilts against Ohio State.

Ohio State vs. Michigan State: 2024 Stats Comparison

	Ohio State	Michigan State
Off. Points per Game (Rank)	52.3 (13)	25.5 (84)
Def. Points per Game (Rank)	6.7 (2)	14.3 (27)
Turnovers Allowed (Rank)	1 (4)	10 (127)
Turnovers Forced (Rank)	3 (96)	5 (60)

Ohio State 2024 Key Players

Name	Position	Stats
Will Howard	QB	795 YDS (68.9%) / 6 TD / 1 INT 22 RUSH YDS / 2 RUSH TD / 7.3 RUSH YPG
Quinshon Judkins	RB	336 YDS / 5 TD / 112 YPG / 9.3 YPC
Jeremiah Smith	WR	14 REC / 281 YDS / 4 TD / 93.7 YPG
TreVeyon Henderson	RB	207 YDS / 4 TD / 69 YPG / 8.6 YPC
Lathan Ransom	DB	10 TKL / 2 TFL
Tyleik Williams	DL	8 TKL / 1 TFL / 1.5 SACK
Caden Curry	DL	2 TKL / 1 TFL / 1 SACK
C.J. Hicks	LB	6 TKL / 1 TFL / 1 SACK

Michigan State 2024 Key Players

Name	Position	Stats
Aidan Chiles	QB	891 YDS (53.8%) / 4 TD / 8 INT 104 RUSH YDS / 3 RUSH TD / 26 RUSH YPG
Kay'Ron Adams	RB	271 YDS / 1 TD / 67.8 YPG / 5.5 YPC
Nick Marsh	WR	11 REC / 232 YDS / 1 TD / 58 YPG
Nathan Carter	RB	207 YDS / 1 TD / 51.8 YPG / 4.4 YPC
Jordan Turner	LB	22 TKL / 6 TFL / 3 SACK
Khris Bogle	DL	17 TKL / 4 TFL / 3 SACK
Angelo Grose	DB	20 TKL / 0 TFL / 1 INT / 1 PD
Cal Haladay	LB	18 TKL / 2 TFL / 1 SACK