Ohio State vs. Northwestern Prediction, Odds, Picks - November 16, 2024

Updated Nov. 14, 2024 9:05 a.m. ET

Data Skrive

Two of the nation's top rushing defenses square off when the No. 2 Ohio State Buckeyes (8-1) bring college football's sixth-ranked rushing defense into a matchup with the Northwestern Wildcats (4-5), who have the No. 15 rushing defense, on Saturday, November 16, 2024. The Buckeyes are double-digit, 28.5-point favorites. The point total is set at 43.5.

In their most recent action, the Buckeyes won versus the Purdue Boilermakers, 45-0. Facing the Purdue Boilermakers in their most recent contest, the Wildcats won 26-20.

Keep up with college football all season on FOX Sports.

Colin & JMac's Big Bets: Iowa (-6) beats UCLA, Penn State (-13.5), Indiana (-14) win | The Herd

Colin Cowherd and Jason McIntyre unveil their Week 11 Big Ten bets, including Iowa (-6) defeating UCLA in Pasadena, Penn State (-13.5) bouncing back on their White Out game against Washington and Indiana (-14) beating Michigan.

Ohio State vs. Northwestern Game Information & Odds

When: Saturday, November 16, 2024 at 12 p.m. ET
Location: Wrigley Field in Chicago, Illinois
TV: BTN
Live Box Score on FOX Sports

More College Football Predictions

Ohio State vs Northwestern Betting Information updated as of November 14, 2024, 8:46 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Ohio State	-28.5 (-112)	-9091	+1563	43.5	-115	-105

Ohio State vs. Northwestern Prediction

Pick ATS: Northwestern (+28.5)
Pick OU: Over (43.5)
Prediction: Ohio State 35, Northwestern 11

Predictions are made by the Data Skrive betting model.

Learn more about the Ohio State Buckeyes vs. the Northwestern Wildcats game on FOX Sports!

Ohio State vs. Northwestern Betting Insights

Per the spread and over/under, the implied score for the matchup is Buckeyes 36, Wildcats 8.
The Buckeyes have a 98.9% chance to win this contest per the moneyline's implied probability. The Wildcats hold a 6.0% implied probability.
Ohio State has compiled a 5-4-0 ATS record so far this year.
Northwestern has covered three times in nine games with a spread this year.

Ohio State vs. Northwestern: 2024 Stats Comparison

	Ohio State	Northwestern
Off. Points per Game (Rank)	38.6 (13)	19.2 (122)
Def. Points per Game (Rank)	10.7 (2)	21.9 (36)
Turnovers Allowed (Rank)	8 (17)	11 (42)
Turnovers Forced (Rank)	13 (56)	13 (56)

Ohio State 2024 Key Players

Name	Position	Stats
Will Howard	QB	2,237 YDS (74%) / 22 TD / 5 INT 128 RUSH YDS / 6 RUSH TD / 14.2 RUSH YPG
Jeremiah Smith	WR	45 REC / 765 YDS / 9 TD / 85 YPG
Quinshon Judkins	RB	647 YDS / 6 TD / 71.9 YPG / 6.1 YPC 12 REC / 94 REC YDS / 1 REC TD / 10.4 REC YPG
Emeka Egbuka	WR	47 REC / 587 YDS / 8 TD / 65.2 YPG
J.T. Tuimoloau	DL	23 TKL / 6 TFL / 5 SACK
Sonny Styles	DB	40 TKL / 4 TFL / 2 SACK
Cody Simon	LB	35 TKL / 5 TFL / 2.5 SACK
Lathan Ransom	DB	30 TKL / 4 TFL / 1 INT / 1 PD

Northwestern 2024 Key Players

Name	Position	Stats
Cam Porter	RB	386 YDS / 6 TD / 42.9 YPG / 4 YPC 18 REC / 127 REC YDS / 0 REC TD / 15.9 REC YPG
Jack Lausch	QB	1,120 YDS (53.6%) / 5 TD / 4 INT 218 RUSH YDS / 1 RUSH TD / 24.2 RUSH YPG
A.J. Henning	WR	40 REC / 426 YDS / 3 TD / 47.3 YPG
Joseph Himon II	RB	230 YDS / 2 TD / 25.6 YPG / 5.2 YPC 13 REC / 91 REC YDS / 1 REC TD / 11.4 REC YPG
Mac Uihlein	LB	58 TKL / 4 TFL / 2 SACK
Theran Johnson	DB	44 TKL / 2 TFL / 2 INT / 3 PD
Xander Mueller	LB	41 TKL / 3 TFL / 1 SACK
Robert Fitzgerald	DB	32 TKL / 0 TFL / 1 INT / 1 PD