Oregon vs. Colorado Prediction, Odds, Picks - September 23

Updated Sep. 23, 2023 3:05 p.m. ET

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Oddsmakers massively favor the No. 10 Oregon Ducks (3-0) when they host the No. 19 Colorado Buffaloes (3-0) on Saturday, September 23, 2023 in a matchup between Pac-12 rivals at Autzen Stadium. Oregon is favored by 21.5 points. A 70.5-point over/under is set for the game.

The Ducks' most recent contest was versus the Hawaii Rainbow Warriors, and they won by a score of 55-10. Last time out, the Buffaloes defeated the Colorado State Rams, with 43-35 being the final score.

Oregon vs. Colorado Game Information & Odds

• When: Saturday, September 23, 2023 at 3:30 PM ET
• Location: Autzen Stadium in Eugene, Oregon
• TV: ABC
• Live boxscore on FOX Sports

Oregon vs. Colorado Prediction

• Pick ATS: Colorado (+21.5)
  
• Pick OU: Under (70.5)
  
• Prediction: Oregon 39, Colorado 30

Learn more about the Oregon Ducks vs. the Colorado Buffaloes game on FOX Sports!

Oregon vs. Colorado Betting Insights

• Based on the spread and over/under, the implied score for the tilt is Ducks 46, Buffaloes 24.
• The Ducks have a 90.3% chance to win this contest per the moneyline's implied probability. The Buffaloes hold a 14.3% implied probability.
• Oregon has won all two of its games against the spread this season.
• Colorado has a record of 2-1-0 against the spread this year.

Oregon vs. Colorado: Head-to-Head

• Over their last two meetings, Oregon has tallied two wins against Colorado.
• In their past two head-to-head meetings, each team has covered one time with those contests going over the point total on one occasion.
• Colorado has been outscored by 62 points in its last two tilts versus Oregon.

Oregon vs. Colorado: 2023 Stats Comparison

Oregon 2023 Key Players

Colorado 2023 Key Players

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CFB - Colorado Buffaloes vs. Oregon Ducks - 09/23/2023

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