Penn State vs. Illinois Prediction, Odds, Picks - September 16

Updated Sep. 16, 2023 9:06 a.m. ET

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Big Ten foes square off when the No. 7 Penn State Nittany Lions (2-0) visit the Illinois Fighting Illini (1-1) on Saturday, September 16, 2023 at Memorial Stadium (Champaign, IL). Penn State is favored by two touchdowns. The contest's point total is set at 48.

Facing the Delaware Fightin' Blue Hens in their most recent contest, the Nittany Lions won 63-7. Last time out, the Fighting Illini fell to the Kansas Jayhawks, with 34-23 being the final score.

Penn State vs. Illinois Game Information & Odds

• When: Saturday, September 16, 2023 at 12:00 PM ET
• Location: Memorial Stadium (Champaign, IL) in Champaign, Illinois
• TV: FOX
• Live boxscore on FOX Sports

Penn State vs. Illinois Prediction

• Pick ATS: Illinois (+14)
  
• Pick OU: Over (48)
  
• Prediction: Penn State 29, Illinois 28

Learn more about the Penn State Nittany Lions vs. the Illinois Fighting Illini game on FOX Sports!

Penn State vs. Illinois Betting Insights

• Per the spread and over/under, the implied score for the tilt is Nittany Lions 31, Fighting Illini 17.
• The Nittany Lions have an 86.1% chance to win this meeting based on the moneyline's implied probability. The Fighting Illini have an 18.3% implied probability.
• Penn State has a record of 1-0-0 against the spread this season.
• Illinois has compiled a 0-2-0 record against the spread this season.

Penn State vs. Illinois: 2023 Stats Comparison

Penn State 2023 Key Players

Illinois 2023 Key Players

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CFB - Penn State Nittany Lions vs. Illinois Fighting Illini - 09/16/2023

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