Penn State vs. USC Prediction, Odds, Picks - October 12, 2024

Updated Oct. 12, 2024 3:04 p.m. ET

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The No. 4 Penn State Nittany Lions (5-0) and the 11th-ranked passing defense will visit the USC Trojans (3-2) and the 21st-ranked pass offense on Saturday, October 12, 2024. The Trojans are 3.5-point underdogs. A total of 52 points has been set for this game.

Facing the UCLA Bruins in their most recent contest, the Nittany Lions won 27-11. The Trojans lost to the Minnesota Golden Gophers, 24-17, in their most recent contest.

Keep up with college football all season on FOX Sports.

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Penn State vs. USC Game Information & Odds

• When: Saturday, October 12, 2024 at 3:30 p.m. ET
• Location: Los Angeles Memorial Coliseum in Los Angeles, California
• TV: CBS
• Live Box Score on FOX Sports

More College Football Predictions

• Illinois vs. Purdue Predictions
• Ohio State vs. Oregon Predictions
• Minnesota vs. UCLA Predictions

Penn State vs. USC Prediction

• Pick ATS: Penn State (-3.5)
  
• Pick OU: Under (52)
  
• Prediction: Penn State 26, USC 21

Predictions are made by the Data Skrive betting model.

Learn more about the Penn State Nittany Lions vs. the USC Trojans game on FOX Sports!

Read More About This Game

• How to Watch Penn State vs. USC

Penn State vs. USC Betting Insights

• Based on the spread and over/under, the implied score for the matchup is Nittany Lions 28, Trojans 24.
• The Nittany Lions have a 64.0% chance to win this contest based on the moneyline's implied probability. The Trojans have a 40.5% implied probability.
• Penn State has a record of 2-3-0 against the spread this season.
• USC has covered three times in five matchups with a spread this season.

Penn State vs. USC: 2024 Stats Comparison

Penn State 2024 Key Players

USC 2024 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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