Penn State vs. USC Prediction, Odds, Picks - October 12, 2024

Updated Oct. 10, 2024 9:05 a.m. ET

Data Skrive

The No. 4 Penn State Nittany Lions (5-0) are 5.5-point favorites on the road at Los Angeles Memorial Coliseum against the USC Trojans (3-2) on Saturday, October 12, 2024. Both teams feature tough pass defenses, with the Nittany Lions 11th against the pass in the nation, and the Trojans 13th defending the passing game. The game's over/under is 50.5.

The Nittany Lions won versus the UCLA Bruins in their most recent game, 27-11. The Trojans' last game was versus the Minnesota Golden Gophers, and they lost by a score of 24-17.

Keep up with college football all season on FOX Sports.

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Penn State vs. USC Game Information & Odds

When: Saturday, October 12, 2024 at 3:30 p.m. ET
Location: Los Angeles Memorial Coliseum in Los Angeles, California
TV: CBS
Live Box Score on FOX Sports

More College Football Predictions

Penn State vs USC Betting Information updated as of October 10, 2024, 7:46 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Penn State	-5.5 (-110)	-207	+168	50.5	-110	-110

Penn State vs. USC Prediction

Pick ATS: USC (+5.5)
Pick OU: Under (50.5)
Prediction: Penn State 26, USC 21

Predictions are made by the Data Skrive betting model.

Learn more about the Penn State Nittany Lions vs. the USC Trojans game on FOX Sports!

Penn State vs. USC Betting Insights

Per the spread and over/under, the implied score for the tilt is Nittany Lions 28, Trojans 22.
The Nittany Lions have a 67.4% chance to claim victory in this game based on the moneyline's implied probability. The Trojans hold a 37.3% implied probability.
Penn State has a record of 2-3-0 against the spread this season.
USC has covered three times in five matchups with a spread this season.

Penn State vs. USC: 2024 Stats Comparison

	Penn State	USC
Off. Points per Game (Rank)	34.4 (41)	30.8 (69)
Def. Points per Game (Rank)	11.4 (7)	18.4 (25)
Turnovers Allowed (Rank)	3 (8)	9 (98)
Turnovers Forced (Rank)	7 (56)	7 (56)

Penn State 2024 Key Players

Name	Position	Stats
Drew Allar	QB	1,101 YDS (70.9%) / 9 TD / 1 INT 89 RUSH YDS / 3 RUSH TD / 17.8 RUSH YPG
Nicholas Singleton	RB	408 YDS / 3 TD / 102 YPG / 7.7 YPC 6 REC / 74 REC YDS / 2 REC TD / 18.5 REC YPG
Tyler Warren	TE	23 REC / 289 YDS / 3 TD / 57.8 YPG
Kaytron Allen	RB	367 YDS / 2 TD / 73.4 YPG / 5 YPC 2 REC / 21 REC YDS / 1 REC TD / 4.2 REC YPG
Jaylen Reed	DB	25 TKL / 1 TFL / 2 SACK
Abdul Carter	DL	14 TKL / 3 TFL / 3 SACK
Tony Rojas	LB	14 TKL / 1 TFL / 0.5 SACK / 1 INT
Dani Dennis-Sutton	DL	6 TKL / 1 TFL / 2 SACK

USC 2024 Key Players

Name	Position	Stats
Jo'Quavious Marks	RB	468 YDS / 4 TD / 93.6 YPG / 5.8 YPC 19 REC / 145 REC YDS / 0 REC TD / 29 REC YPG
Miller Moss	QB	1,398 YDS (64.5%) / 9 TD / 4 INT -20 RUSH YDS / 1 RUSH TD / -4 RUSH YPG
Ja'Kobi Lane	WR	21 REC / 234 YDS / 4 TD / 46.8 YPG
Quinten Joyner	RB	212 YDS / 2 TD / 42.4 YPG / 7.9 YPC
Eric Gentry	LB	23 TKL / 5 TFL / 2 SACK
Kamari Ramsey	DB	18 TKL / 2 TFL / 1 SACK
Mason Cobb	LB	10 TKL / 1 TFL / 2 INT / 2 PD
Easton Mascarenas	LB	13 TKL / 0 TFL / 1 INT / 1 PD