Astros vs. Mariners Prediction, Odds, Picks - September 25

Updated Sep. 25, 2024 2:01 p.m. ET

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The Houston Astros and Seattle Mariners will play on Wednesday at Minute Maid Park, at 2:10 p.m. ET, with Yordan Alvarez and Randy Arozarena among those expected to produce at the plate. The Astros are favored in this one, at -132, while the underdog Mariners have +112 odds to upset. Houston is the run-line favorite (-1.5). A 7-run over/under has been listed in the contest.

Here's everything you need from a betting perspective on the Astros-Mariners game, regarding the run line, moneyline and total, plus expert picks.

Josh Hader strikes out Mariners' Julio Rodríguez to make the Astros AL West Champions

Josh Hader picked up a strikeout on Seattle Mariners' Julio Rodríguez to make the Houston Astros AL West Champions.

Astros vs. Mariners Game Information & Odds

• When: Wednesday, September 25, 2024 at 2:10 p.m. ET
• Where: Minute Maid Park in Houston, Texas
• How to Watch on TV: SCHN

Astros vs. Mariners Prediction

• Score Prediction: Astros 5, Mariners 4
• Total Prediction: Over 7 runs
• Win Probabilities: Astros 54%, Mariners 46%

Astros vs. Mariners Betting Insights

• This season, the Astros have been favored 117 times and won 67, or 57.3%, of those games.
• Houston has a record of 52-33 in games when bookmakers favor them by at least -132 on the moneyline.
• The moneyline for this contest implies a 56.9% chance of a victory for the Astros.
• The Mariners have been chosen as underdogs in 50 games this year and have walked away with the win 21 times (42%) in those games.
• This year, Seattle has won 10 of 22 games when listed as at least +112 or worse on the moneyline.
• The moneyline set for this matchup implies the Mariners have a 47.2% chance of walking away with the win.

FINAL

SEA 8 · HOU 1

MLB

RUN LINE

TO WIN

TOTAL

Seattle Mariners

SEA

-1.5

-159

O 7

Houston Astros

HOU

+1.5

+134

U 7

Astros Recent Betting Performance

• The Astros were favored on the moneyline in seven of their last 10 games, and they finished 5-2 in those matchups.
• Over their last 10 matchups, the Astros and their opponents combined to hit the over on the total four times (all 10 games had set totals).
• The Astros are 5-5-0 against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Not only does Alvarez lead the Astros in hitting with his .308 average, he also paces the squad with 35 home runs and 86 RBI.
• Among all MLB hitters, Alvarez ranks sixth in batting average, fourth in on-base percentage, and fifth in slugging.
• Alvarez brings a hitting streak of two games into this matchup. In his last five games he is batting .333 with two doubles, a home run, two walks and an RBI.
• Jose Altuve has 29 doubles, 20 home runs and 46 walks while hitting .293.
• Altuve ranks 73rd in homers and 80th in RBI among all MLB hitters this season.
• Alex Bregman has 28 doubles, two triples, 26 home runs and 44 walks while batting .257.
• Yainer Diaz has 29 doubles, three triples, 16 home runs and 23 walks while batting .302.
• Diaz has recorded at least one hit in six games in a row. During his last 10 outings he is hitting .279 with three doubles and three RBI.

Astros Team Props

Learn more about this Astros vs. Mariners matchup on Fox Sports.

Mariners Recent Betting Performance

• In five games as underdogs over the last 10 matchups, the Mariners have a record of 2-3.
• In their last 10 games with a total, the Mariners and their opponents are 5-3-2 when it comes to hitting the over.
• The Mariners are 6-4-0 ATS over their last 10 games.

Mariners Recent Stats

Mariners Player Insights

• Cal Raleigh has managed a team-high 31 home runs and has driven in 96 runs.
• Raleigh's home run total places him 15th in MLB, and he is 18th in RBI.
• Raleigh has collected a hit in four games in a row. During his last five outings he is hitting .333 with a home run, two walks and three RBI.
• Arozarena is hitting .222 with 32 doubles, 20 home runs and 72 walks.
• Arozarena ranks 73rd overall in home runs and 103rd in RBI this year.
• Julio Rodriguez has racked up a team-best batting average of .275.
• Justin Turner has 23 doubles, 11 home runs and 59 walks while batting .259.

Mariners Team Props

Josh Hader strikes out Mariners' Julio Rodríguez to make the Astros AL West Champions

Josh Hader picked up a strikeout on Seattle Mariners' Julio Rodríguez to make the Houston Astros AL West Champions.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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