Cardinals vs. Brewers Prediction, Odds, Picks - April 27

The Milwaukee Brewers and Christian Yelich take the field in the final game of a three-game series against Lars Nootbaar and the St. Louis Cardinals, on Sunday at Busch Stadium. The Brewers are -109 moneyline underdogs for this matchup with the favorite Cardinals (-110). Milwaukee is favored on the run line (-1.5). The contest's over/under is listed at 8 runs.

Check out everything you need from a betting perspective on the Cardinals-Brewers game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Brewers vs. Cardinals Highlights | MLB on FOX

Check out the best highlights between the the Milwaukee Brewers and the St. Louis Cardinals.

Cardinals vs. Brewers Game Information & Odds

• When: Sunday, April 27, 2025 at 2:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMWX and FDSWI

Cardinals vs. Brewers Prediction

• Score Prediction: Cardinals 6, Brewers 5
• Total Prediction: Over 8 runs
• Win Probabilities: Cardinals 51%, Brewers 49%

Cardinals vs. Brewers Betting Insights

• The Cardinals have entered the game as favorites eight times this season and won four of those games.
• St. Louis has a record of 4-4 when favored by -110 or more by bookmakers this season.
• The implied probability of a win from the Cardinals, based on the moneyline, is 52.4%.
• The Brewers have been underdogs in 14 games this season and have come away with the win three times (21.4%) in those contests.
• Milwaukee has a mark of 3-11 in contests where oddsmakers favor it by -109 or worse on the moneyline.
• The moneyline set for this matchup implies the Brewers have a 52.2% chance of coming away with a victory in the contest.

Cardinals Recent Betting Performance

• The Cardinals played three of their last 10 games as a moneyline favorite, and won all of them.
• In their last 10 outings, the Cardinals and their opponents combined to hit the over five times (all 10 of the games had set totals).
• The Cardinals are 4-6-0 against the spread over their past 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• The Cardinals' best power option comes in the form of Nootbaar and his four-home-run 17-RBI season, both team highs.
• Nootbaar is 55th in home runs and 29th in RBI among all hitters in baseball.
• Nootbaar takes a hitting streak of two games into this matchup. During his last five outings he is hitting .300 with a double, a home run, five walks and six RBI.
• Brendan Donovan's .367 batting average leads his team.
• Donovan is 95th in home runs and 41st in RBI among all batters in baseball.
• Donovan enters this matchup looking for his fifth game in a row with a hit. During his last five outings he is batting .316 with two doubles, two walks and two RBI.
• Nolan James Arenado is hitting .266 with eight doubles, three home runs and 14 walks.
• Arenado has at least one base hit in three games in a row. During his last five outings he is hitting .190 with two doubles, a home run, two walks and two RBI.
• Victor Scott II has five doubles, a triple, a home run and eight walks while batting .264.

Cardinals Team Props

Brewers Recent Betting Performance

• In six games as underdogs over the last 10 matchups, the Brewers have a record of 1-5.
• When it comes to hitting the over, the Brewers and their opponents are 4-5-1 in their last 10 games with a total.
• The Brewers are 7-3-0 ATS over their last 10 games.

Brewers Recent Stats

Brewers Player Insights

• Jackson Chourio leads the Brewers with six long balls and runs batted in, driving in 23.
• Chourio ranks 23rd in homers and seventh in RBI among all hitters in the big leagues.
• Brice Turang's .321 batting average is a team-high mark.
• Turang is currently 95th in homers and 52nd in RBI in the big leagues.
• Yelich is hitting .227 with three doubles, five home runs and 15 walks.
• Sal Frelick is hitting .303 with four doubles, two triples, a home run and 11 walks.

Brewers Team Props

Brewers vs. Cardinals Highlights | MLB on FOX

Check out the best highlights between the the Milwaukee Brewers and the St. Louis Cardinals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

St. Louis Cardinals

Milwaukee Brewers