Cardinals vs. Diamondbacks Prediction, Odds, Picks - April 22

Updated Apr. 22, 2024 7:00 p.m. ET

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Brandon Pfaadt takes the mound for the Arizona Diamondbacks on Monday at Busch Stadium against Willson Contreras and the St. Louis Cardinals. First pitch is at 7:45 PM ET for the first game of a three-game series. The Cardinals are the favorite in this one, at -114, while the underdog Diamondbacks have -105 odds to win. Arizona is a 1.5-run favorite (at +155 odds). An 8.5-run total has been set in the contest.

Take a look at everything you need from a betting perspective on the Cardinals-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

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Cardinals vs. Diamondbacks Game Information & Odds

• When: Monday, April 22, 2024 at 7:45 PM ET
• Where: Busch Stadium in St. Louis, Missouri
• How to Watch on TV: ARID

Cardinals vs. Diamondbacks Prediction

• Score Prediction: Cardinals 5, Diamondbacks 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Cardinals 51%, Diamondbacks 49%

Cardinals vs. Diamondbacks Betting Insights

• This season, the Cardinals have been favored nine times and won four of those games.
• St. Louis has a record of 4-5 in games when oddsmakers favor them by at least -114 on the moneyline.
• The Cardinals have a 53.3% chance to win this game based on the implied probability of the moneyline.
• The Diamondbacks have won in two of the eight contests they have been named as odds-on underdogs this year.
• This season, Arizona has been victorious two times in eight chances when named as an underdog of at least -105 or longer on the moneyline.
• The moneyline set for this matchup implies the Diamondbacks have a 51.2% chance of walking away with the win.

FINAL

AZ 3 · STL 5

MLB

RUN LINE

TO WIN

TOTAL

Arizona Diamondbacks

AZ

-1.5

-105

O 8.5

St. Louis Cardinals

STL

+1.5

-114

U 8.5

Cardinals Recent Betting Performance

• The Cardinals were the moneyline favorite for five of their last 10 games, and they finished 2-3 in those matchups.
• In their last 10 outings, the Cardinals and their opponents combined to go over the run total three times (all 10 games had set totals).
• The Cardinals have put together a 4-6-0 record against the spread over their past 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Nolan Arenado is hitting .291 with six doubles, a home run and six walks.
• Arenado's home runs place him 166th in MLB, and he ranks 73rd in RBI.
• Brendan Donovan's 12 runs batted in lead his team.
• Donovan ranks 104th in homers and 58th in RBI among all hitters in baseball.
• Contreras has six doubles, two home runs and 10 walks while hitting .305.
• Contreras has at least one base hit in 14 straight games. During his last 10 outings he is batting .361 with five doubles, six walks and three RBI.
• Masyn Winn is hitting .317 to pace his team.

Cardinals Team Props

Learn more about this Cardinals vs. Diamondbacks matchup on Fox Sports.

Diamondbacks Recent Betting Performance

• The Diamondbacks have played as underdogs in three of their past 10 games and have gone 2-1 in those contests.
• In their last 10 games with a total, the Diamondbacks and their opponents have combined to hit the over four times.
• Over their last 10 games, the Diamondbacks are 4-6-0 against the spread.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Ketel Marte has a team-best batting average of .340, and leads the Diamondbacks in long balls with five.
• Marte's home run total places him 17th in the majors, and he is 40th in RBI.
• Lourdes Gurriel Jr. has been a reliable source of runs this year, leading the lineup with five home runs and 21 runs batted in.
• Gurriel is 17th among all batters in the majors in home runs, and fourth in RBI.
• Christian Walker is hitting .259 with two doubles, three home runs and 15 walks.
• Corbin Carroll has two doubles, a home run and 14 walks while batting .216.

Diamondbacks Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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