Cubs vs. Cardinals Prediction, Odds, Picks - May 25

Updated May. 25, 2024 7:00 p.m. ET

Data Skrive

Masyn Winn and Seiya Suzuki hit the field when the St. Louis Cardinals and Chicago Cubs meet on Saturday at Busch Stadium. The Cubs are -142 moneyline favorites in this matchup against the Cardinals (+120). Chicago (-1.5) is the favorite on the run line. The total is 7.5 runs for this contest.

Here is everything you need to know from a betting perspective on the Cubs-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

Red Sox vs. Cardinals Highlights | MLB on FOX

Check out the best moments from the Boston Red Sox vs. St. Louis Cardinals game on Friday, May 17.

Cubs vs. Cardinals Game Information & Odds

When: Saturday, May 25, 2024 at 7:15 PM ET
Where: Busch Stadium in St. Louis, Missouri
How to Watch on TV: FOX

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Cubs	-142	+120	7.5	-117	-104	-1.5	+122	-146

Cubs vs. Cardinals Prediction

Score Prediction: Cardinals 6, Cubs 5
Total Prediction: Over 7.5 runs
Win Probabilities: Cubs 51%, Cardinals 49%

Cubs vs. Cardinals Betting Insights

The Cubs have entered the game as favorites 20 times this season and won 11, or 55%, of those games.
Chicago has entered seven games this season favored by -142 or more, and won each of those games.
The bookmakers' moneyline implies a 58.7% chance of a victory for the Cubs.
The Cardinals have been chosen as underdogs in 23 games this year and have walked away with the win 10 times (43.5%) in those games.
This year, St. Louis has won three of eight games when listed as at least +120 or worse on the moneyline.
The moneyline set for this matchup implies the Cardinals have a 45.5% chance of coming away with a victory in the contest.

Cubs Recent Betting Performance

The Cubs went 1-3 over the four games they were favored on the moneyline in their last 10 matchups.
In their last 10 outings, the Cubs and their opponents combined to hit the over three times (all 10 of the games had set totals).
The Cubs' ATS record is 2-8-0 over their past 10 games.

Cubs Recent Stats

Stat	Avg/Total
Record	3-7
Runs Per Game	2.3
HR	4
ERA	3.34
K/9	9.9

Cubs Player Insights

Christopher Morel paces the Cubs in home runs (nine) and runs batted in (33).
Morel is 25th in homers and 19th in RBI among all hitters in baseball.
Nico Hoerner is hitting .257 to pace his team.
Hoerner ranks 234th in home runs and 213th in RBI among all MLB hitters this year.
Mike Tauchman paces the Cubs with a .257 batting average.
Cody Bellinger is batting .241 with seven doubles, a triple, seven home runs and 16 walks.

Learn more about this Cubs vs. Cardinals matchup on Fox Sports.

Cardinals Recent Betting Performance

The Cardinals have played as underdogs in five of their past 10 games and won three of those contests.
In their last 10 games with a total, the Cardinals and their opponents are 8-1-1 when it comes to hitting the over.
Over their last 10 games, the Cardinals are 6-4-0 against the spread.