Cubs vs. Nationals Prediction, Odds, Picks - September 22

Updated Sep. 21, 2024 5:00 p.m. ET

Data Skrive

Ian Happ and Keibert Ruiz will be among the stars on display when the Chicago Cubs play the Washington Nationals on Sunday at 2:20 p.m. ET, at Wrigley Field. The Cubs are -195 moneyline favorites in this matchup against the Nationals (+163). Chicago is the favorite on the run line (-1.5). The matchup's total is set at 8.5 runs.

Here is everything you need from a betting perspective on the Cubs-Nationals game, regarding the run line, moneyline and total, plus expert picks.

Nationals vs. Cubs Highlights | MLB on FOX

Check out the top moments between the Washington Nationals and the Chicago Cubs.

Cubs vs. Nationals Game Information & Odds

When: Sunday, September 22, 2024 at 2:20 p.m. ET
Where: Wrigley Field in Chicago, Illinois
How to Watch on TV: MARQ

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Cubs	-195	+163	8.5	-105	-115	-1.5	+101	-121

Cubs vs. Nationals Prediction

Score Prediction: Cubs 4, Nationals 3
Total Prediction: Under 8.5 runs
Win Probabilities: Cubs 59%, Nationals 41%

Cubs vs. Nationals Betting Insights

The Cubs have won 40, or 53.3%, of the 75 games they've played as favorites this season.
Chicago is undefeated in nine games this season when favored by -195 or more on the moneyline.
The moneyline for this contest implies a 66.1% chance of a victory for the Cubs.
The Nationals have won in 52, or 41.6%, of the 125 contests they have been named as odds-on underdogs this year.
Washington has a win-loss record of 13-13 when favored by +163 or worse by bookmakers this year.
The Nationals have an implied victory probability of 38% according to the moneyline set for this matchup.

Cubs Recent Betting Performance

The Cubs went 4-4 across the eight games they were favored on the moneyline in their last 10 matchups.
In their last 10 outings (all 10 of them had set totals), the Cubs and their opponents combined to hit the over seven times.
The Cubs have gone 4-6-0 against the spread over their past 10 games.

Cubs Recent Stats

Stat	Avg/Total
Record	5-5
Runs Per Game	5.5
HR	13
ERA	4.80
K/9	8.0

Cubs Player Insights

Happ leads the Cubs in home runs (25) and runs batted in (85).
Among all hitters in baseball, Happ is 31st in homers and 30th in RBI.
Nico Hoerner is batting .271 with 32 doubles, a triple, five home runs and 44 walks.
Hoerner ranks 290th in home runs and 191st in RBI on the year.
Hoerner has eight games in a row with at least one hit. During his last 10 outings he is batting .421 with two doubles, three walks and two RBI.
Cody Bellinger is batting .268 with 23 doubles, two triples, 18 home runs and 44 walks.
Isaac Paredes has 24 doubles, a triple, 19 home runs and 73 walks while hitting .235.

Learn more about this Cubs vs. Nationals matchup on Fox Sports.

Nationals Recent Betting Performance

The Nationals have played as underdogs in six of their past 10 games and have gone 1-5 in those contests.
In their last 10 games with a total, the Nationals and their opponents are 3-6-1 when it comes to hitting the over.
The Nationals are 5-5-0 ATS over their last 10 games.

Nationals Recent Stats

Stat	Avg/Total
Record	4-6
Runs Per Game	2.9
HR	9
ERA	4.08
K/9	7.9

Nationals Player Insights

Luis Garcia leads the squad with a batting average of .280, while leading the Nationals in home runs, with 16 and runs batted in with 65.
Among all batters in the big leagues, Garcia is 111th in homers and 78th in RBI.
Ruiz is hitting .228 with 21 doubles, 13 home runs and 16 walks.
Ruiz is 145th in home runs and 139th in RBI among all major league batters this year.
Jacob Young is hitting .254 with 23 doubles, a triple, three home runs and 28 walks.
James Wood is batting .267 with 12 doubles, three triples, eight home runs and 37 walks.