Dodgers vs. Giants Prediction, Odds, Picks - September 22

Updated Sep. 22, 2023 10:00 p.m. ET

Data Skrive

The Los Angeles Dodgers and San Francisco Giants will send Caleb Ferguson and Sean Manaea, respectively, out to start when the two clubs face off on Friday at Dodger Stadium, at 10:10 PM ET. The favored Dodgers have -171 moneyline odds to win against the underdog Giants, who are listed at +145. Los Angeles (-1.5) is the favorite on the run line. The over/under for the game is set at 9 runs.

The starting pitchers are Ferguson (7-3) for the Los Angeles Dodgers, and Manaea (6-6) for the San Francisco Giants.

Here is everything you need from a betting perspective on the Dodgers-Giants game, from the point spread, moneyline, Over/Under and expert picks.

Dodgers vs. Giants Game Information & Odds

When: Friday, September 22, 2023 at 10:10 PM ET
Where: Dodger Stadium in Los Angeles, California
How to Watch on TV: Apple TV+

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Dodgers	-171	+145	9	-104	-115	-1.5	+119	-142

Dodgers vs. Giants Prediction

Score Prediction: Dodgers 6, Giants 3
Total Prediction: Over 9 runs
Win Probabilities: Dodgers 67%, Giants 33%

Dodgers vs. Giants Betting Insights

This season, the Dodgers have been favored 127 times and won 81, or 63.8%, of those games.
Los Angeles is 33-17 this season when entering a game favored by -171 or more on the moneyline.
The Dodgers have a 63.1% chance to win this game based on the implied probability of the moneyline.
The Giants have been chosen as underdogs in 71 games this year and have walked away with the win 32 times (45.1%) in those games.
This season, San Francisco has been victorious three times in 11 chances when named as an underdog of at least +145 or worse on the moneyline.
The moneyline set for this matchup implies the Giants have a 40.8% chance of walking away with the win.

Dodgers Recent Betting Performance

The Dodgers went 6-3 over the nine games they were favored on the moneyline in their last 10 matchups.
In their last 10 matchups -- all had a set run total -- the Dodgers and their opponents combined to go over the total five times.
The Dodgers are 6-4-0 against the spread over their past 10 games.

Dodgers Recent Stats

Stat	Avg/Total
Record	7-3
Runs Per Game	5.8
HR	16
ERA	3.03
K/9	10.6

Dodgers Player Insights

Mookie Betts is the Dodgers best power hitter, crushing 39 home runs this season in addition to accumulating 103 RBI, both team highs.
Of all batters in the majors, Betts ranks fifth in home runs and fourth in RBI.
Freddie Freeman has a club-high .336 batting average.
Freeman is 34th in homers and 15th in RBI among all batters in MLB.
Max Muncy is batting .211 with 16 doubles, a triple, 36 home runs and 79 walks.
Will Smith has 21 doubles, two triples, 18 home runs and 62 walks while batting .262.
Smith brings a two-game streak with at least one hit into this one. During his last five outings he is hitting .111 with a triple, a walk and an RBI.

Learn more about this Dodgers vs. Giants matchup on Fox Sports.

Giants Recent Betting Performance

Over the past 10 games, the Giants have been underdogs twice and lost both games.
In their last 10 games with a total, the Giants and their opponents have failed to hit the over three times.
The Giants have not covered in any of their last 10 games with a spread.

Giants Recent Stats

Stat	Avg/Total
Record	3-7
Runs Per Game	3.9
HR	8
ERA	4.70
K/9	7

Giants Player Insights

Wilmer Flores paces the Giants with 22 long balls.
Flores' home run total places him 65th in the big leagues, and he ranks 127th in RBI.
LaMonte Wade Jr has 14 doubles, two triples, 16 home runs and 72 walks while batting .262.
Wade is 126th in homers and 190th in RBI among all hitters in MLB.
Thairo Estrada leads the Giants with a team-best batting average of .276.
J.D. Davis has driven in the most runs for the Giants with 69 runs batted in.