Giants vs. Cardinals Prediction, Odds, Picks - September 28

Updated Sep. 28, 2024 4:01 p.m. ET

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Mike Yastrzemski and the San Francisco Giants will take on Alec Burleson and the St. Louis Cardinals at Oracle Park on Saturday. The Giants are favored in this one, at -136, while the underdog Cardinals have +116 odds to win. San Francisco is favored on the run line (-1.5). The total for the contest has been set at 7.5 runs.

Take a look at everything you need to know from a betting perspective on the Giants-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Cardinals Game Information & Odds

• When: Saturday, September 28, 2024 at 4:05 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to Watch on TV: BSMW

Giants vs. Cardinals Prediction

• Score Prediction: Giants 5, Cardinals 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Giants 58%, Cardinals 42%

Giants vs. Cardinals Betting Insights

• The Giants have won 45, or 57.7%, of the 78 games they've played as favorites this season.
• San Francisco is 27-16 this season when entering a game favored by -136 or more on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Giants have a 57.6% chance to win.
• The Cardinals have won in 41, or 50.6%, of the 81 contests they have been named as odds-on underdogs this year.
• This season, St. Louis has come away with a win 13 times in 32 chances when named as an underdog of at least +116 or longer on the moneyline.
• The moneyline set for this matchup implies the Cardinals have a 46.3% chance of walking away with the win.

FINAL

STL 5 · SF 6

MLB

RUN LINE

TO WIN

TOTAL

St. Louis Cardinals

STL

+1.5

+110

O 7.5

San Francisco Giants

SF

-1.5

-130

U 7.5

Giants Recent Betting Performance

• The Giants were named the moneyline favorite by bookmakers just twice over the last 10 games, and split those matchups.
• Over their last 10 outings -- all had a set run total -- the Giants and their opponents combined to hit the over on the total seven times.
• The Giants' ATS record is 7-3-0 over their past 10 games.

Giants Recent Stats

Giants Player Insights

• The Giants' best power option comes in the form of Matt Chapman and his 27-home-run 78-RBI season, both team highs.
• Including all MLB batters, Chapman is 85th in batting average, 59th in on-base percentage, and 39th in slugging.
• Heliot Ramos is batting .270 to lead his team.
• Ramos ranks 56th in home runs in the majors, and 67th in RBI.
• Michael Conforto has 27 doubles, three triples, 20 home runs and 42 walks while hitting .237.
• Conforto has at least one base hit in five straight games. In his last five games he is batting .350 with two doubles, two home runs, a walk and four RBI.
• Yastrzemski is batting .234 with 16 doubles, nine triples, 18 home runs and 38 walks.
• Yastrzemski is riding a three-game hitting streak into this one. In his last five games he is hitting .227 with two doubles, a home run and four RBI.

Giants Team Props

Learn more about this Giants vs. Cardinals matchup on Fox Sports.

Cardinals Recent Betting Performance

• The Cardinals have been underdogs twice in the last 10 games and won both contests.
• In their last 10 games with a total, the Cardinals and their opponents are 4-6-0 when it comes to hitting the over.
• The Cardinals have six wins against the spread in their last 10 chances.

Cardinals Recent Stats

Cardinals Player Insights

• Burleson has driven in a team-leading 75 runs batted in.
• Among all batters in MLB, Burleson ranks 63rd in homers and 52nd in RBI.
• Brendan Donovan has a club-best .273 batting average.
• Donovan is 153rd among all hitters in the big leagues in homers, and 76th in RBI.
• Masyn Winn is hitting .268 with 31 doubles, five triples, 15 home runs and 40 walks.
• Nolan Arenado has 23 doubles, 16 home runs and 44 walks while batting .272.

Cardinals Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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