Giants vs. Padres Prediction, Odds, Picks - April 5

Updated Apr. 5, 2024 4:01 p.m. ET

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Wilmer Flores and Fernando Tatis Jr. will be among the star attractions when the San Francisco Giants play the San Diego Padres on Friday at 4:35 PM ET, at Oracle Park. Oddsmakers list the Giants as -115 moneyline favorites, while giving the underdog Padres -105 moneyline odds. San Diego is the run-line favorite (-1.5). The over/under for the game has been listed at 7.5 runs.

Here is everything you need from a betting perspective on the Giants-Padres game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Padres Game Information & Odds

• When: Friday, April 5, 2024 at 4:35 PM ET
• Where: Oracle Park in San Francisco, California
• How to Watch on TV: NBCS-BA

Giants vs. Padres Prediction

• Score Prediction: Giants 7, Padres 6
• Total Prediction: Over 7.5 runs
• Win Probabilities: Giants 50%, Padres 50%

Giants vs. Padres Betting Insights

• The Giants have not played a game this season while listed as the favorite.
• San Francisco has not entered a game this season as bigger favorites on the moneyline than the -115 odds on them winning this game.
• Bookmakers have implied with the moneyline set for this matchup that the Giants have a 53.5% chance to win.
• The Padres have split the two games they've played as underdogs this season.
• San Diego has been listed as an underdog of -105 or more on two occasions this season and split those games.
• The moneyline set for this matchup implies the Padres have a 51.2% chance of coming away with a victory in the contest.

FINAL

SD 2 · SF 3

MLB

RUN LINE

TO WIN

TOTAL

San Diego Padres

SD

+1.5

+102

O 7.5

San Francisco Giants

SF

-1.5

-121

U 7.5

Giants Player Insights

• Michael Conforto leads the Giants with three home runs and nine runs batted in, while putting up a team-best batting average of .370.
• Conforto ranks third in homers and fifth in RBI among all batters in the majors.
• Conforto takes a hitting streak of three games into this matchup. In his last five games he is hitting .333 with a double, two home runs, two walks and eight RBI.
• Jorge Soler has two doubles, two home runs and five walks while hitting .280.
• Soler ranks 14th in homers and 94th in RBI on the year.
• Soler has three games in a row with at least one hit. In his last five games he is hitting .333 with a double, two home runs, three walks and three RBI.
• Matt Chapman has two doubles, two home runs and two walks while hitting .233.
• Jung Hoo Lee has a home run and three walks while hitting .250.

Giants Team Props

Learn more about this Giants vs. Padres matchup on Fox Sports.

Padres Player Insights

• Tatis leads the Padres with three long balls.
• Among all hitters in MLB, Tatis is third in home runs and 36th in RBI.
• Luis Campusano has a club-best seven runs batted in and .400 batting average.
• Campusano is 49th in homers and 15th in RBI among all hitters in the big leagues.
• Manny Machado has collected a team-best seven runs batted in.
• Ha-Seong Kim is hitting .242 with two doubles, a home run and five walks.

Padres Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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