Guardians vs. Astros Prediction, Odds, Picks - September 27

Updated Sep. 27, 2024 7:01 p.m. ET

Data Skrive

Kyle Manzardo and the Cleveland Guardians will square off against Yordan Alvarez and the Houston Astros at Progressive Field on Friday. The Guardians are favored in this one, at -124, while the underdog Astros have +104 odds to play spoiler. Cleveland is favored on the run line (-1.5 with +173 odds). The game's total has been listed at 8 runs.

Here's everything you need to know from a betting perspective on the Guardians-Astros game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Astros Game Information & Odds

When: Friday, September 27, 2024 at 7:10 p.m. ET
Where: Progressive Field in Cleveland, Ohio
How to Watch on TV: MLB Network

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Guardians	-124	+104	8	-111	-109	-1.5	+173	-207

Guardians vs. Astros Prediction

Score Prediction: Guardians 5, Astros 4
Total Prediction: Over 8 runs
Win Probabilities: Guardians 53%, Astros 47%

Guardians vs. Astros Betting Insights

This season, the Guardians have been favored 99 times and won 65, or 65.7%, of those games.
Cleveland has a record of 51-24 in games when bookmakers favor them by at least -124 on the moneyline.
The implied probability of a win from the Guardians, based on the moneyline, is 55.4%.
The Astros have been chosen as underdogs in 42 games this year and have walked away with the win 19 times (45.2%) in those games.
Houston has a win-loss record of 10-11 when favored by +104 or worse by sportsbooks this year.
The Astros have an implied victory probability of 49% according to the moneyline set by sportsbooks for this matchup.

Guardians Recent Betting Performance

The Guardians have a 4-2 record from the six games they were moneyline favorites over their last 10 matchups.
Over their last 10 matchups (all had set totals), the Guardians combined with their opponents to hit the over on the total two times.
The Guardians have put together a 7-3-0 record against the spread over their past 10 games.

Guardians Recent Stats

Stat	Avg/Total
Record	7-3
Runs Per Game	3.7
HR	14
ERA	1.70
K/9	8.9

Guardians Player Insights

Jose Ramirez is the Guardians best power option, launching 38 round-trippers this season in addition to accumulating 115 RBI, both team highs.
Ramirez ranks sixth in home runs and third in RBI among all hitters in baseball.
Ramirez takes a hitting streak of two games into this matchup. During his last five outings he is batting .500 with three doubles, a triple, three home runs and eight RBI.
Josh Naylor has 27 doubles, 31 home runs and 57 walks while hitting .243.
Naylor is 15th in homers and seventh in RBI on the year.
Naylor has two straight games with at least one hit. In his last five games he is hitting .188 with a double, two walks and three RBI.
Steven Kwan has accumulated a team-best batting average of .292.
Kwan is on a five-game hitting streak entering this contest. In his last five games he is hitting .412 with a home run, six walks and an RBI.
Andres Gimenez has 22 doubles, a triple, nine home runs and 26 walks while hitting .253.

Guardians Team Props

	Hits O/U	Total Bases O/U	HR O/U	RBI O/U
Will Brennan	0.5 (-215)	1.5 (+150)	-	0.5 (+185)
Steven Kwan	0.5 (-270)	1.5 (+120)	-	0.5 (+210)
Andrés Giménez	0.5 (-235)	1.5 (+135)	-	0.5 (+210)
José Ramírez	0.5 (-240)	1.5 (+105)	-	0.5 (+140)
Josh Naylor	0.5 (-230)	1.5 (+125)	-	0.5 (+150)

Learn more about this Guardians vs. Astros matchup on Fox Sports.

Astros Recent Betting Performance

The Astros have played as underdogs in four of their past 10 games and won one of those contests.
The Astros and their opponents have combined to hit the over four times in their last 10 games with a total.
The Astros have a record of 4-6-0 ATS over their last 10 games.

Astros Recent Stats

Stat	Avg/Total
Record	5-5
Runs Per Game	4.1
HR	12
ERA	4.35
K/9	10

Astros Player Insights

Alvarez leads the squad with a batting average of .308, and leads the Astros in home runs, with 35 and runs batted in with 86.
Alvarez's home run total places him 10th in the big leagues, and he is 30th in RBI.
Jose Altuve has 29 doubles, 20 home runs and 46 walks while hitting .293.
Among all major league hitters, Altuve is 75th in homers and 85th in RBI.
Alex Bregman is batting .256 with 28 doubles, two triples, 26 home runs and 44 walks.
Yainer Diaz has 29 doubles, three triples, 16 home runs and 23 walks while batting .299.

Astros Team Props

	Hits O/U	Total Bases O/U	HR O/U	RBI O/U
Alex Bregman	0.5 (-260)	1.5 (+105)	-	0.5 (+140)
Kyle Tucker	0.5 (-245)	1.5 (+105)	-	0.5 (+140)
Yainer Diaz	1.5 (+175)	1.5 (-105)	-	0.5 (+130)
Victor Caratini	0.5 (-215)	1.5 (+140)	-	0.5 (+175)
Jeremy Pena	1.5 (+190)	1.5 (+105)	-	0.5 (+165)