Guardians vs. Padres Prediction, Odds, Picks - July 21

Updated Jul. 21, 2024 1:01 p.m. ET

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The San Diego Padres and Manny Machado take the field at Progressive Field against Josh Naylor and the Cleveland Guardians on Sunday. Oddsmakers list the Guardians as -113 moneyline favorites, while giving the underdog Padres -106 moneyline odds. San Diego is the run-line favorite (-1.5). The over/under is 7.5 runs for this matchup.

Here's everything you need to know from a betting perspective on the Guardians-Padres game, regarding the run line, moneyline and total, plus expert picks.

Padres vs. Guardians Highlights | MLB on FOX

Check out the top moments from this game between the San Diego Padres and the Cleveland Guardians.

Guardians vs. Padres Game Information & Odds

• When: Sunday, July 21, 2024 at 1:40 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: SDPA

Guardians vs. Padres Prediction

• Score Prediction: Guardians 4, Padres 3
• Total Prediction: Under 7.5 runs
• Win Probabilities: Guardians 56%, Padres 44%

Guardians vs. Padres Betting Insights

• This season, the Guardians have won 44 out of the 65 games, or 67.7%, in which they've been favored.
• Cleveland has a record of 38-19, a 66.7% win rate, when favored by -113 or more by sportsbooks this season.
• The moneyline for this contest implies a 53.1% chance of a victory for the Guardians.
• The Padres have won in 21, or 50%, of the 42 contests they have been named as odds-on underdogs this year.
• This year, San Diego has won 21 of 39 games when listed as at least -106 or worse on the moneyline.
• The Padres have an implied victory probability of 51.5% according to the moneyline set by oddsmakers for this matchup.

FINAL

SD 2 · CLE 1

MLB

RUN LINE

TO WIN

TOTAL

San Diego Padres

SD

+1.5

-108

O 7.5

Cleveland Guardians

CLE

-1.5

-112

U 7.5

Guardians Recent Betting Performance

• The Guardians were the moneyline favorite in seven of their last 10 games, and finished 4-3 in those matchups.
• Over their last 10 outings, the Guardians and their opponents combined to hit the over four times (all 10 of the games had set totals).
• The Guardians are 2-8-0 against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez leads the Guardians with 23 home runs and 79 runs batted in.
• Ramirez's home runs place him sixth in MLB, and he ranks second in RBI.
• Naylor has 16 doubles, 22 home runs and 36 walks while hitting .241.
• Naylor is ninth in home runs and fourth in RBI on the season.
• Steven Kwan leads the Guardians with a .351 batting average.
• Andres Gimenez has 13 doubles, a triple, five home runs and 17 walks while hitting .246.

Guardians Team Props

Learn more about this Guardians vs. Padres matchup on Fox Sports.

Padres Recent Betting Performance

• In five games over the last 10 matchups when set as underdogs by bookmakers, the Padres had a record of 2-3.
• The Padres and their opponents have combined to hit the over five times in their last 10 games with a total.
• The Padres have a record of 3-7-0 ATS over their last 10 games.

Padres Recent Stats

Padres Player Insights

• Jurickson Profar paces the Padres in home runs (14) and runs batted in (59).
• Among all batters in MLB, Profar ranks 53rd in homers and 25th in RBI.
• Jake Cronenworth has racked up a team-high 14 home runs.
• Cronenworth ranks 53rd among all hitters in MLB in home runs, and 27th in RBI.
• Luis Arraez has a team-high batting average of .312.
• Ha-Seong Kim has 12 doubles, three triples, 10 home runs and 49 walks while hitting .224.

Padres Team Props

Padres vs. Guardians Highlights | MLB on FOX

Check out the top moments from this game between the San Diego Padres and the Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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MLB - San Diego Padres vs. Cleveland Guardians - 07/21/2024

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