Guardians vs. Reds Prediction, Odds, Picks - September 25

Updated Sep. 25, 2024 6:01 p.m. ET

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The Cleveland Guardians and Cincinnati Reds will meet on Wednesday at Progressive Field, at 6:40 p.m. ET, with Josh Naylor and Elly De La Cruz among those expected to step up at the plate. The Guardians have been listed as -147 moneyline favorites for this matchup against the Reds (+124). Cleveland (-1.5) is the favorite on the run line. An 8-run total has been listed for the game.

Here is everything you need from a betting perspective on the Guardians-Reds game, regarding the run line, moneyline and total, plus expert picks.

Reds vs. Guardians Highlights | MLB on FOX

Check out the best moments and plays from the Cincinnati Reds and Cleveland Guardians game on September 24th, 2024.

Guardians vs. Reds Game Information & Odds

• When: Wednesday, September 25, 2024 at 6:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL

Guardians vs. Reds Prediction

• Score Prediction: Guardians 5, Reds 4
• Total Prediction: Over 8 runs
• Win Probabilities: Guardians 59%, Reds 41%

Guardians vs. Reds Betting Insights

• This season, the Guardians have won 64 out of the 98 games, or 65.3%, in which they've been favored.
• Cleveland is 23-13 this season when entering a game favored by -147 or more on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Guardians have a 59.5% chance to win.
• The Reds have been underdogs in 88 games this season and have come away with the win 40 times (45.5%) in those contests.
• This season, Cincinnati has come away with a win 18 times in 35 chances when named as an underdog of at least +124 or longer on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Reds have a 44.6% chance of pulling out a win.

FINAL

CIN 2 · CLE 5

MLB

RUN LINE

TO WIN

TOTAL

Cincinnati Reds

CIN

+1.5

+124

O 8

Cleveland Guardians

CLE

-1.5

-148

U 8

Guardians Recent Betting Performance

• The Guardians went 4-2 over the six games they were moneyline favorites in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Guardians combined with their opponents to go over the total two times.
• The Guardians' ATS record is 7-3-0 over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez is the Guardians best power option, crushing 37 round-trippers this season in addition to collecting 112 RBI, both team highs.
• Among all batters in baseball, Ramirez's home run total places him eighth, and his RBI tally puts him third.
• Naylor is batting .243 with 27 doubles, 31 home runs and 57 walks.
• Naylor ranks 15th in homers in MLB, and seventh in RBI.
• Steven Kwan has accumulated a team-best batting average of .291.
• Kwan has at least one base hit in four games in a row. During his last five outings he is hitting .313 with seven walks.
• Andres Gimenez is batting .255 with 22 doubles, a triple, nine home runs and 26 walks.

Guardians Team Props

Learn more about this Guardians vs. Reds matchup on Fox Sports.

Reds Recent Betting Performance

• The Reds have played as underdogs in seven of their past 10 games and won three of those contests.
• In their last 10 games with a total, the Reds and their opponents have combined to hit the over six times.
• The Reds have five wins against the spread in their last 10 chances.

Reds Recent Stats

Reds Player Insights

• De La Cruz paces the Reds with 25 home runs.
• De La Cruz ranks 35th in homers and 52nd in RBI among all hitters in the majors.
• Spencer Steer has driven in the most runs for the Reds with 92 runs batted in.
• Steer ranks 73rd in homers and 22nd in RBI among all hitters in the big leagues.
• Jonathan India has 28 doubles, two triples, 15 home runs and 77 walks while hitting .247.
• Tyler Stephenson leads the Reds with a .262 batting average.

Reds Team Props

Reds vs. Guardians Highlights | MLB on FOX

Check out the best moments and plays from the Cincinnati Reds and Cleveland Guardians game on September 24th, 2024.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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MLB - Cincinnati Reds vs. Cleveland Guardians - 09/25/2024

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