Guardians vs. Reds Prediction, Odds, Picks - September 26

Updated Sep. 26, 2023 6:06 p.m. ET

Data Skrive

The Cleveland Guardians versus Cincinnati Reds game on Tuesday at 6:10 PM ET will feature a pair of hot hitters in Andres Gimenez and TJ Friedl. The Guardians are -120 moneyline favorites in this matchup with the Reds (+101). Cleveland is the favorite on the run line (-1.5 with +168 odds). A 7.5-run total is set in this matchup.

The scheduled starters are Lucas Giolito (8-14) for the Cleveland Guardians, and Hunter Greene (4-6) for the Cincinnati Reds.

Here's everything you need from a betting perspective on the Guardians-Reds game, from the point spread, moneyline, Over/Under and expert picks.

Guardians vs. Reds Game Information & Odds

When: Tuesday, September 26, 2023 at 6:10 PM ET
Where: Progressive Field in Cleveland, Ohio
How to Watch on TV: BSGL

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Guardians	-120	+101	7.5	-113	-107	-1.5	+168	-202

Guardians vs. Reds Prediction

Score Prediction: Guardians 6, Reds 5
Total Prediction: Over 7.5 runs
Win Probabilities: Guardians 52%, Reds 48%

Guardians vs. Reds Betting Insights

The Guardians have won 38, or 50.7%, of the 75 games they've played as favorites this season.
This season Cleveland has won 31 of its 63 games, or 49.2%, when favored by at least -120 on the moneyline.
The Guardians have a 54.5% chance to win this game based on the implied probability of the moneyline.
The Reds have been underdogs in 115 games this season and have come away with the win 57 times (49.6%) in those contests.
Cincinnati has a win-loss record of 44-51 when favored by +101 or worse by sportsbooks this year.
The Reds have an implied victory probability of 49.8% according to the moneyline set for this matchup.

Guardians Recent Betting Performance

The Guardians played as the moneyline favorite in six of their last 10 games, and they went 2-4 in those matchups.
Over their last 10 matchups -- all had a set run total -- the Guardians and their opponents combined to go over the total five times.
The Guardians have gone 4-6-0 against the spread over their past 10 games.

Guardians Recent Stats

Stat	Avg/Total
Record	5-5
Runs Per Game	5.1
HR	7
ERA	3.83
K/9	9.7

Guardians Player Insights

Jose Ramirez has put up a team-best batting average of .279, and leads the Guardians in home runs (24).
Ramirez is 50th in homers and 49th in RBI among all hitters in the majors.
Steven Kwan has 35 doubles, seven triples, five home runs and 68 walks while hitting .272.
Kwan is 307th in home runs and 146th in RBI among all MLB batters this season.
Josh Naylor has a team-high 95 runs batted in.
Gimenez is batting .250 with 27 doubles, five triples, 14 home runs and 32 walks.

Learn more about this Guardians vs. Reds matchup on Fox Sports.

Reds Recent Betting Performance

The Reds have played as underdogs in six of their past 10 games and won three of those contests.
In their last 10 games with a total, the Reds and their opponents are 5-4-1 when it comes to hitting the over.
The Reds have three wins against the spread in their last 10 chances.

Reds Recent Stats

Stat	Avg/Total
Record	4-6
Runs Per Game	4.5
HR	15
ERA	5.73
K/9	9.8

Reds Player Insights

Spencer Steer leads the Reds with 22 long balls and runs batted in, driving in 83.
Among all hitters in the big leagues, Steer ranks 67th in homers and 43rd in RBI.
Friedl is batting .280 to lead the lineup.
Friedl ranks 117th overall in homers and 108th in RBI this season.
Jonathan India is batting .242 with 21 doubles, 16 home runs and 49 walks.
Jake Fraley is batting .259 with 18 doubles, 15 home runs and 37 walks.