Guardians vs. Reds Prediction, Odds, Picks - September 27

Updated Sep. 27, 2023 6:00 p.m. ET

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Christian Encarnacion-Strand and Andres Gimenez take the field when the Cincinnati Reds and Cleveland Guardians meet on Wednesday at Progressive Field. The Guardians are favored in this one, at -127, while the underdog Reds have +108 odds to upset. Cleveland (-1.5) is the favorite on the run line. The matchup's over/under has been set at 8 runs.

The Cleveland Guardians will hand the ball to Shane Bieber (5-6, 3.91 ERA), who is looking for win No. 6 on the season, and the Reds will counter with Andrew Abbott (8-5, 3.70 ERA).

Here's everything you need to know from a betting perspective on the Guardians-Reds game, from the point spread, moneyline, Over/Under and expert picks.

Guardians vs. Reds Game Information & Odds

• When: Wednesday, September 27, 2023 at 6:10 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL

Guardians vs. Reds Prediction

• Score Prediction: Guardians 5, Reds 4
• Total Prediction: Over 8 runs
• Win Probabilities: Guardians 52%, Reds 48%

Guardians vs. Reds Betting Insights

• This season, the Guardians have been favored 76 times and won 38, or 50%, of those games.
• Cleveland has a record of 26-29, a 47.3% win rate, when favored by -127 or more by bookmakers this season.
• The moneyline for this contest implies a 55.9% chance of a victory for the Guardians.
• The Reds have been victorious in 58, or 50%, of the 116 contests they have been chosen as underdogs in this season.
• This season, Cincinnati has been victorious 39 times in 82 chances when named as an underdog of at least +108 or worse on the moneyline.
• The Reds have an implied victory probability of 48.1% according to the moneyline set for this matchup.

Guardians Recent Betting Performance

• The Guardians have a 2-5 record from the seven games they were favored on the moneyline over their last 10 matchups.
• In their last 10 outings (all had set totals), the Guardians combined with their opponents to hit the over on the total five times.
• The Guardians have put together a 3-7-0 record against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez's .279 average and 24 homers both put him atop the Guardians leaderboard this season.
• Ramirez ranks 51st in homers and 50th in RBI among all hitters in the majors.
• Ramirez carries a two-game hitting streak into this matchup. During his last five outings he is hitting .381 with a double, two walks and two RBI.
• Steven Kwan has 35 doubles, seven triples, five home runs and 68 walks while hitting .270.
• Kwan ranks 312th in homers and 147th in RBI in the bigs.
• Josh Naylor paces the Guardians with 96 runs batted in.
• Gimenez is hitting .252 with 27 doubles, five triples, 15 home runs and 32 walks.

Guardians Team Props

Learn more about this Guardians vs. Reds matchup on Fox Sports.

Reds Recent Betting Performance

• In six games as underdogs over the last 10 matchups, the Reds have a record of 4-2.
• In their last 10 games with a total, the Reds and their opponents have combined to hit the over five times.
• The Reds have four wins against the spread in their last 10 chances.

Reds Recent Stats

Reds Player Insights

• Spencer Steer paces the Reds with 22 long balls and runs batted in, driving in 84.
• Among all hitters in the big leagues, Steer's home run total is 67th and his RBI tally is 41st.
• TJ Friedl's .280 batting average paces his team.
• Friedl ranks 107th in home runs and 108th in RBI among all major league hitters this season.
• Jonathan India is hitting .240 with 21 doubles, 16 home runs and 50 walks.
• Jake Fraley is batting .259 with 18 doubles, 15 home runs and 37 walks.

Reds Team Props

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MLB - Cincinnati Reds vs. Cleveland Guardians - 09/27/2023

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