Nationals vs. Orioles Prediction, Odds, Picks - April 24

The Washington Nationals and James Wood will hit the field against the Baltimore Orioles and Heston Kjerstad on Thursday at 6:45 p.m. ET, in the final game of a three-game series at Nationals Park. The Orioles are +102 moneyline underdogs for this matchup with the favored Nationals (-121). Washington (-1.5) is favored on the run line. The matchup's over/under has been listed at 8.5 runs.

Take a look at everything you need from a betting perspective on the Nationals-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Nationals Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Washington Nationals.

Nationals vs. Orioles Game Information & Odds

• When: Thursday, April 24, 2025 at 6:45 p.m. ET
• Where: Nationals Park in Washington D.C.
• How to watch on TV: MLB Network, MASN, and MASN2

Nationals vs. Orioles Prediction

• Score Prediction: Nationals 7, Orioles 6
• Total Prediction: Over 8.5 runs
• Win Probabilities: Nationals 53%, Orioles 47%

Nationals vs. Orioles Betting Insights

• The Nationals have been favorites in five games this season and won two (40%) of those contests.
• Washington has played as favorites of -121 or more twice this season and split those games.
• The Nationals have a 54.8% chance to win this game based on the implied probability of the moneyline.
• The Orioles have been victorious in four of the nine contests they have been chosen as underdogs in this season.
• This season, Baltimore has been victorious two times in five chances when named as an underdog of at least +102 or worse on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Orioles have a 49.5% chance of pulling out a win.

Nationals Recent Betting Performance

• The Nationals were favored on the moneyline in three of their last 10 games, and they finished 1-2 in those matchups.
• Over their last 10 outings (all 10 of them had set totals), the Nationals and their opponents combined to hit the over three times.
• The Nationals have a 4-6-0 record against the spread over their past 10 games.

Nationals Recent Stats

Nationals Player Insights

• Wood's eight homers in 2025 are the most on the Nationals. He's also driven in 18 runs while hitting .256.
• Wood's home runs rank him fourth in the majors, and he is 18th in RBI.
• Wood takes a hitting streak of two games into this game. In his last five games he is hitting .350 with two doubles, two home runs, two walks and five RBI.
• Keibert Ruiz's .325 batting average leads his team.
• Ruiz is 129th in homers in baseball, and 53rd in RBI.
• Ruiz carries a four-game streak with at least one hit into this contest. In his last five games he is batting .300 with two doubles and two RBI.
• Nate Lowe has a team-high 19 runs batted in.
• Lowe is on a four-game hitting streak entering this contest. During his last five outings he is batting .316 with a home run, two walks and three RBI.
• Luis Garcia has three doubles, a home run and six walks while hitting .216.

Nationals Team Props

Orioles Recent Betting Performance

• Over the past 10 games, oddsmakers have not installed the Orioles as underdogs once.
• In their last 10 games with a total, the Orioles and their opponents have combined to hit the over six times.
• Over their last 10 games, the Orioles are 3-7-0 against the spread.

Orioles Recent Stats

Orioles Player Insights

• Cedric Mullins leads the lineup with a batting average of .297, and leads the Orioles in home runs, with six and runs batted in with 19.
• Among all hitters in the majors, Mullins is 17th in home runs and 12th in RBI.
• Mullins has collected a hit in five straight games. In his last five games he is hitting .316 with two home runs, four walks and two RBI.
• Adley Rutschman is hitting .214 with two doubles, four home runs and 12 walks.
• Rutschman is currently 48th in homers and 154th in RBI in the big leagues.
• Ryan O'Hearn has three doubles, three home runs and six walks while hitting .281.
• Jordan Westburg is batting .190 with two doubles, a triple, four home runs and five walks.

Orioles Team Props

Orioles vs. Nationals Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Washington Nationals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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