Orioles vs. Guardians Prediction, Odds, Picks - September 23

Updated Sep. 23, 2023 6:00 p.m. ET

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Cal Quantrill takes the mound for the Cleveland Guardians on Saturday at Progressive Field against Adley Rutschman and the Baltimore Orioles. First pitch is at 6:10 PM ET. The favored Orioles have -132 moneyline odds against the underdog Guardians, who are listed at +111. Baltimore is the favorite on the run line (-1.5). The over/under is 8 runs for the game (with -118 odds to hit the over and -102 odds to go under).

The matchup on the mound for this contest is set with the Baltimore Orioles looking to John Means (0-1), and Quantrill (3-6) taking the ball for the Cleveland Guardians.

Take a look at everything you need from a betting perspective on the Orioles-Guardians game, from the point spread, moneyline, Over/Under and expert picks.

Orioles vs. Guardians Game Information & Odds

• When: Saturday, September 23, 2023 at 6:10 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: BSGL

Orioles vs. Guardians Prediction

• Score Prediction: Orioles 5, Guardians 4
• Total Prediction: Over 8 runs
• Win Probabilities: Orioles 51%, Guardians 49%

Orioles vs. Guardians Betting Insights

• This season, the Orioles have been favored 78 times and won 52, or 66.7%, of those games.
• Baltimore has a record of 40-15 in games when bookmakers favor them by at least -132 on the moneyline.
• The implied probability of a win from the Orioles, based on the moneyline, is 56.9%.
• The Guardians have been underdogs in 79 games this season and have come away with the win 36 times (45.6%) in those contests.
• This season, Cleveland has been victorious 20 times in 51 chances when named as an underdog of at least +111 or longer on the moneyline.
• The Guardians have an implied victory probability of 47.4% according to the moneyline set for this matchup.

Orioles Recent Betting Performance

• The Orioles were favored on the moneyline for five of their last 10 games, and they went 1-4 in those matchups.
• In their last 10 matchups, the Orioles and their opponents combined to hit the over on the run total four times (all 10 games had set totals).
• The Orioles have put together a 5-5-0 record against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• Rutschman is batting .273 with 29 doubles, a triple, 19 home runs and 85 walks.
• Rutschman's home runs place him 94th in MLB, and he is 61st in RBI.
• Rutschman takes a hitting streak of six games into this game. During his last 10 outings he is batting .282 with five doubles, a home run, four walks and five RBI.
• Gunnar Henderson's 27 home runs are a team-high mark.
• Among all MLB batters, Henderson ranks 31st in homers and 44th in RBI.
• Anthony Santander paces the Orioles with 27 home runs and 89 runs batted in.
• Austin Hays is batting .276 to lead his team.

Learn more about this Orioles vs. Guardians matchup on Fox Sports.

Guardians Recent Betting Performance

• The Guardians have played as underdogs in five of their past 10 games and won four of those contests.
• When it comes to hitting the over, the Guardians and their opponents are 6-4-0 in their last 10 games with a total.
• The Guardians have won five of their last 10 games against the spread.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez paces the Guardians with 24 homers while racking up a team-best batting average of .278.
• Among all hitters in the big leagues, Ramirez ranks 48th in home runs and 46th in RBI.
• Steven Kwan is hitting .276 with 35 doubles, seven triples, five home runs and 68 walks.
• Kwan is 306th among all hitters in MLB in homers, and 142nd in RBI.
• Josh Naylor has a team-best 95 runs batted in.
• Andres Gimenez has 27 doubles, five triples, 13 home runs and 32 walks while batting .251.

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MLB - Baltimore Orioles vs. Cleveland Guardians - 09/23/2023

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