Orioles vs. Tigers Prediction, Odds, Picks - September 22

Updated Sep. 21, 2024 10:00 p.m. ET

Data Skrive

Anthony Santander and the Baltimore Orioles will meet Riley Greene and the Detroit Tigers on Sunday at Oriole Park at Camden Yards, at 1:35 p.m. ET. The Orioles are the favorite in this one, at -134, while the underdog Tigers have +114 odds to win. Baltimore is favored on the run line (-1.5 with +159 odds). The total is 8.5 runs for this matchup (with -105 odds on the over and -115 odds on the under).

Check out everything you need from a betting perspective on the Orioles-Tigers game, regarding the run line, moneyline and total, plus expert picks.

Tigers vs. Orioles Highlights | MLB on FOX

Check out the top moments between the Detroit Tigers and the Baltimore Orioles.

Orioles vs. Tigers Game Information & Odds

When: Sunday, September 22, 2024 at 1:35 p.m. ET
Where: Oriole Park at Camden Yards in Baltimore, Maryland
How to Watch on TV: MASN

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Orioles	-134	+114	8.5	-105	-115	-1.5	+159	-190

Orioles vs. Tigers Prediction

Score Prediction: Orioles 5, Tigers 4
Total Prediction: Under 8.5 runs
Win Probabilities: Orioles 53%, Tigers 47%

Orioles vs. Tigers Betting Insights

The Orioles have won 67, or 57.8%, of the 116 games they've played as favorites this season.
Baltimore has entered 85 games this season favored by -134 or more and is 49-36 in those contests.
The Orioles have a 57.3% chance to win this game based on the implied probability of the moneyline.
The Tigers have come away with 45 wins in the 93 contests they have been listed as the underdogs in this season.
This year, Detroit has won 23 of 57 games when listed as at least +114 or worse on the moneyline.
Sportsbooks have implied with the moneyline set for this matchup that the Tigers have a 46.7% chance of pulling out a win.

Orioles Recent Betting Performance

The Orioles have a 3-4 record from the seven games they were favored on the moneyline over their last 10 matchups.
In their last 10 outings (all 10 of them had set totals), the Orioles and their opponents combined to hit the over four times.
The Orioles are 4-6-0 against the spread over their past 10 games.

Orioles Recent Stats

Stat	Avg/Total
Record	4-6
Runs Per Game	3.3
HR	12
ERA	3.54
K/9	10.0

Orioles Player Insights

Gunnar Henderson's .282 average leads the Orioles this year. His resume also includes 37 homers and driven in 89 RBI.
Henderson's home runs put him seventh in the majors, and he is 24th in RBI.
Henderson brings a hitting streak of four games into this matchup. In his last five games he is batting .304 with two doubles and two RBI.
Santander's 43 home runs and 99 runs batted in are both team-highs.
Santander is third in home runs and 12th in RBI among all major league hitters this season.
Adley Rutschman has 19 doubles, a triple, 19 home runs and 57 walks while hitting .250.
Ryan O'Hearn has 20 doubles, three triples, 13 home runs and 45 walks while hitting .259.
O'Hearn has recorded at least one hit in four straight games. In his last five games he is hitting .357 with two doubles, a walk and an RBI.

Learn more about this Orioles vs. Tigers matchup on Fox Sports.

Tigers Recent Betting Performance

The Tigers have played as underdogs in seven of their past 10 games and won five of those contests.
In their last 10 games with a total, the Tigers and their opponents have combined to hit the over four times.
The Tigers are 7-3-0 ATS over their last 10 games.

Tigers Recent Stats

Stat	Avg/Total
Record	7-3
Runs Per Game	3.7
HR	8
ERA	3.36
K/9	8.8

Tigers Player Insights

Greene leads the Tigers with 24 home runs and 72 runs batted in, while posting a team-best batting average of .264.
Among all hitters in the big leagues, Greene's home run total is 40th and his RBI tally ranks 53rd.
Matt Vierling has 27 doubles, five triples, 16 home runs and 36 walks while hitting .259.
Vierling is 111th overall in homers and 121st in RBI this season.
Colt Keith leads the Tigers with a team-best batting average of .264.
Wenceel Perez is hitting .238 with 15 doubles, five triples, nine home runs and 28 walks.