Orioles vs. White Sox Prediction, Odds, Picks - May 25

Updated May. 25, 2024 2:00 p.m. ET

Data Skrive

The Baltimore Orioles and Chicago White Sox play on Saturday at 2:10 PM ET. Gunnar Henderson and Andrew Vaughn have been on a tear as of late for their respective teams. Oddsmakers list the Orioles as -172 favorites on the moneyline, while giving the underdog White Sox +144 moneyline odds to win. Baltimore is the run-line favorite (-1.5). The total is 8 runs for this game.

Here's everything you need from a betting perspective on the Orioles-White Sox game, regarding the run line, moneyline and total, plus expert picks.

Orioles vs. White Sox Highlights | MLB on FOX

Check out the greatest plays in this matchup between the Baltimore Orioles and the Chicago White Sox.

Orioles vs. White Sox Game Information & Odds

When: Saturday, May 25, 2024 at 2:10 PM ET
Where: Guaranteed Rate Field in Chicago, Illinois
How to Watch on TV: MASN

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Orioles	-172	+144	8	-114	-106	-1.5	-106	-113

Orioles vs. White Sox Prediction

Score Prediction: Orioles 4, White Sox 3
Total Prediction: Under 8 runs
Win Probabilities: Orioles 57%, White Sox 43%

Orioles vs. White Sox Betting Insights

This season, the Orioles have been favored 39 times and won 24, or 61.5%, of those games.
Baltimore has a record of 6-4 in games when bookmakers favor them by at least -172 on the moneyline.
Sportsbooks have implied with the moneyline set for this matchup that the Orioles have a 63.2% chance to win.
The White Sox have been victorious in 13, or 26%, of the 50 contests they have been chosen as underdogs in this season.
This season, Chicago has come away with a win eight times in 35 chances when named as an underdog of at least +144 or longer on the moneyline.
The White Sox have an implied victory probability of 41% according to the moneyline set by sportsbooks for this matchup.

Orioles Recent Betting Performance

The Orioles have a 5-4 record across the nine games they were favored on the moneyline in their last 10 matchups.
In their last 10 matchups, the Orioles and their opponents combined to hit the over six times (all 10 of the games had set totals).
The Orioles have put together a 4-6-0 record against the spread over their past 10 games.

Orioles Recent Stats

Stat	Avg/Total
Record	5-5
Runs Per Game	4.5
HR	12
ERA	3.48
K/9	7.5

Orioles Player Insights

Henderson has racked up a team-best 17 home runs and 37 runs batted in.
In all of MLB, Henderson is first in home runs and eighth in RBI.
Henderson brings a hitting streak of three games into this game. In his last five games he is hitting .294 with a double, two home runs, six walks and six RBI.
Adley Rutschman has a club-best .303 batting average.
Rutschman ranks 25th in homers and 19th in RBI on the year.
Rutschman has three games in a row with at least one hit. In his last five games he is batting .235 with a walk and five RBI.
Jordan Westburg is batting .274 with 10 doubles, three triples, seven home runs and 14 walks.
Anthony Santander is batting .202 with 11 doubles, a triple, eight home runs and 14 walks.

Learn more about this Orioles vs. White Sox matchup on Fox Sports.

White Sox Recent Betting Performance

In nine games as underdogs over the last 10 matchups, the White Sox have a record of 2-7.
The White Sox and their opponents have combined to hit the over five times in their last 10 games with a total.
Over their last 10 games, the White Sox are 3-7-0 against the spread.

White Sox Recent Stats

Stat	Avg/Total
Record	3-7
Runs Per Game	3.1
HR	6
ERA	4.98
K/9	8.7

White Sox Player Insights

Gavin Sheets leads the White Sox with a team-leading batting average of .241.
Among all hitters in the big leagues, Sheets' home run total ranks 189th and his RBI tally is 194th.
Tommy Pham is batting .327 with seven doubles, three home runs and six walks.
Pham is 189th overall in homers and 226th in RBI this year.
Vaughn has racked up a team-high 18 runs batted in.
Paul DeJong has swatted a team-leading seven long balls.