Padres vs. Giants Prediction, Odds, Picks - September 25

Updated Sep. 25, 2023 9:00 p.m. ET

Data Skrive

Juan Soto and the San Diego Padres will try to defeat Wilmer Flores and the San Francisco Giants at Oracle Park on Monday at 9:45 PM ET. The favored Padres have -123 moneyline odds to win against the underdog Giants, who are listed at +104. San Diego is favored on the run line (-1.5). A 7-run over/under has been listed for this matchup.

The San Diego Padres will hand the ball to Blake Snell (14-9, 2.38 ERA), who is looking for win No. 15 on the season, and the Giants will counter with Logan Webb (10-13, 3.48 ERA).

Take a look at everything you need to know from a betting perspective on the Padres-Giants game, from the point spread, moneyline, Over/Under and expert picks.

Padres vs. Giants Game Information & Odds

When: Monday, September 25, 2023 at 9:45 PM ET
Where: Oracle Park in San Francisco, California
How to Watch on TV: Fox Sports 1

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Padres	-123	+104	7	-106	-114	-1.5	+147	-175

Padres vs. Giants Prediction

Score Prediction: Padres 5, Giants 4
Total Prediction: Over 7 runs
Win Probabilities: Padres 51%, Giants 49%

Padres vs. Giants Betting Insights

The Padres have been favorites in 116 games this season and won 64 (55.2%) of those contests.
San Diego has a record of 58-38, a 60.4% win rate, when favored by -123 or more by bookmakers this season.
The moneyline for this contest implies a 55.2% chance of a victory for the Padres.
The Giants have been chosen as underdogs in 74 games this year and have walked away with the win 33 times (44.6%) in those games.
This season, San Francisco has come away with a win 19 times in 51 chances when named as an underdog of at least +104 or longer on the moneyline.
The moneyline set for this matchup implies the Giants have a 49% chance of walking away with the win.

Padres Recent Betting Performance

The Padres were the moneyline favorite for nine of their last 10 games, and finished 8-1 in those matchups.
In their last 10 outings (all 10 of them had set totals), the Padres and their opponents combined to go over the run total four times.
The Padres' record against the spread is 8-2-0 over their past 10 games.

Padres Recent Stats

Stat	Avg/Total
Record	9-1
Runs Per Game	6.3
HR	14
ERA	2.45
K/9	11.1

Padres Player Insights

Soto leads the Padres with 33 home runs and 105 runs batted in.
Of all hitters in the majors, Soto's home run total places him 15th, and his RBI tally puts him fifth.
Soto brings a hitting streak of three games into this game. In his last five games he is hitting .444 with three doubles, a home run, four walks and five RBI.
Fernando Tatis Jr. has 32 doubles, a triple, 25 home runs and 52 walks while hitting .264.
Tatis is 44th in home runs and 56th in RBI among all hitters in baseball.
Tatis heads into this game looking for his fourth game in a row with a hit. During his last five outings he is hitting .263 with a double, two walks and an RBI.
Xander Bogaerts leads the Padres with a .282 batting average.
Bogaerts will look to build on his two-game hitting in this game. In his last five games he is batting .348 with two doubles, a triple, a home run, a walk and four RBI.
Manny Machado has 21 doubles, 30 home runs and 50 walks while hitting .253.
Machado has recorded at least one hit in two straight games. In his last five games he is hitting .333 with a double, two home runs, two walks and four RBI.

Learn more about this Padres vs. Giants matchup on Fox Sports.

Giants Recent Betting Performance

In five games as underdogs over the last 10 matchups, the Giants have a record of 1-4.
In their last 10 games with a total, the Giants and their opponents have combined to hit the over five times.
The Giants have two wins against the spread in their last 10 chances.

Giants Recent Stats

Stat	Avg/Total
Record	2-8
Runs Per Game	3.4
HR	9
ERA	5.30
K/9	7.6

Giants Player Insights

Flores leads the Giants with 22 long balls.
Flores' home run total places him 67th in the big leagues, and he is 133rd in RBI.
LaMonte Wade Jr is hitting .262 with 14 doubles, two triples, 17 home runs and 73 walks.
Wade is 117th in homers and 186th in RBI among all batters in the big leagues.
Thairo Estrada leads the Giants with a team-high batting average of .275.
J.D. Davis has collected a team-leading 69 runs batted in.