Padres vs. White Sox Prediction, Odds, Picks - September 22

Updated Sep. 22, 2024 4:00 p.m. ET

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The San Diego Padres and Manny Machado ready for the final of a three-game series against Andrew Benintendi and the Chicago White Sox on Sunday at PETCO Park. The White Sox are +248 moneyline underdogs in this matchup with the Padres (-310). San Diego is a 1.5-run favorite (at -141 odds). The over/under for the matchup has been set at 8 runs.

Here's everything you need from a betting perspective on the Padres-White Sox game, regarding the run line, moneyline and total, plus expert picks.

White Sox vs. Padres Highlights | MLB on FOX

Check out the greatest plays and moments in this matchup between the Chicago White Sox and the San Diego Padres.

Padres vs. White Sox Game Information & Odds

• When: Sunday, September 22, 2024 at 4:10 p.m. ET
• Where: PETCO Park in San Diego, California
• How to Watch on TV: SDPA

Padres vs. White Sox Prediction

• Score Prediction: Padres 5, White Sox 3
• Total Prediction: Over 8 runs
• Win Probabilities: Padres 64%, White Sox 36%

Padres vs. White Sox Betting Insights

• The Padres have been favorites in 101 games this season and won 60 (59.4%) of those contests.
• San Diego has played as favorites of -310 or more once this season and won that game.
• The moneyline for this contest implies a 75.6% chance of a victory for the Padres.
• The White Sox have won in 32, or 21.8%, of the 147 contests they have been named as odds-on underdogs this year.
• This season, Chicago has been victorious two times in 12 chances when named as an underdog of at least +248 or longer on the moneyline.
• The White Sox have an implied victory probability of 28.7% according to the moneyline set by sportsbooks for this matchup.

FINAL

CWS 2 · SD 4

MLB

RUN LINE

TO WIN

TOTAL

Chicago White Sox

CWS

+1.5

+275

O 8

San Diego Padres

SD

-1.5

-351

U 8

Padres Recent Betting Performance

• The Padres were the moneyline favorite in nine of their last 10 games, and they went 7-2 in those matchups.
• In their last 10 matchups, the Padres and their opponents combined to go over the run total two times (all 10 of the games had set totals).
• The Padres have gone 6-4-0 against the spread over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Jurickson Profar is hitting .283 with 28 doubles, 23 home runs and 75 walks.
• Profar's home runs rank him 44th in MLB, and he is 35th in RBI.
• Profar brings a hitting streak of two games into this matchup. During his last five outings he is hitting .389 with two doubles, a home run, a walk and an RBI.
• Manny Machado has hit 29 home runs with 104 RBI. Both are team-highs.
• Machado is 22nd in home runs and eighth in RBI among all MLB batters this season.
• Jackson Merrill has 29 doubles, six triples, 24 home runs and 28 walks while hitting .294.
• Merrill will look to build on his three-game hitting in this matchup. In his last five games he is hitting .471 with two doubles, a home run, three walks and four RBI.
• Luis Arraez's .317 batting average is a team-high mark.

Padres Team Props

Learn more about this Padres vs. White Sox matchup on Fox Sports.

White Sox Recent Betting Performance

• In 10 games as underdogs over the last 10 matchups, the White Sox have a record of 3-7.
• In their last 10 games with a total, the White Sox and their opponents have failed to hit the over seven times.
• The White Sox have a record of 5-5-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Andrew Vaughn leads the White Sox with 19 home runs and 67 runs batted in, while posting a team-high batting average of .246.
• Vaughn is 82nd in homers and 74th in RBI among all hitters in MLB.
• Andrew Benintendi has shown off his power as he leads his team with 19 home runs.
• Benintendi ranks 82nd among all hitters in the majors in home runs, and 101st in RBI.
• Gavin Sheets has 24 doubles, a triple, 10 home runs and 43 walks while batting .236.
• Nicky Lopez has 12 doubles, three triples, a home run and 37 walks while batting .243.

White Sox Team Props

White Sox vs. Padres Highlights | MLB on FOX

Check out the greatest plays and moments in this matchup between the Chicago White Sox and the San Diego Padres.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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MLB - Chicago White Sox vs. San Diego Padres - 09/22/2024

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