Red Sox vs. Guardians Prediction, Odds, Picks - April 16

Updated Apr. 16, 2024 7:00 p.m. ET

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The Boston Red Sox and Tyler O'Neill ready for the second of a four-game series against Jose Ramirez and the Cleveland Guardians on Tuesday at Fenway Park. Oddsmakers list the Red Sox as -120 favorites on the moneyline, while giving the underdog Guardians +101 moneyline odds to win. Boston is the favorite on the run line (-1.5). The contest's over/under has been set at 8 runs.

Take a look at everything you need to know from a betting perspective on the Red Sox-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Guardians Game Information & Odds

• When: Tuesday, April 16, 2024 at 7:10 PM ET
• Where: Fenway Park in Boston, Massachusetts
• How to Watch on TV: NESN

Red Sox vs. Guardians Prediction

• Score Prediction: Guardians 5, Red Sox 4
• Total Prediction: Over 8 runs
• Win Probabilities: Red Sox 51%, Guardians 49%

Red Sox vs. Guardians Betting Insights

• The Red Sox have been favorites in nine games this season and won six (66.7%) of those contests.
• Boston has a record of 4-1 in games when oddsmakers favor them by at least -120 on the moneyline.
• The Red Sox have a 54.5% chance to win this game based on the implied probability of the moneyline.
• The Guardians have come away with six wins in the seven contests they have been listed as the underdogs in this season.
• Cleveland has a win-loss record of 5-1 when favored by +101 or worse by oddsmakers this year.
• Sportsbooks have implied with the moneyline set for this matchup that the Guardians have a 49.8% chance of pulling out a win.

FINAL (11)

CLE 10 · BOS 7

MLB

RUN LINE

TO WIN

TOTAL

Cleveland Guardians

CLE

+1.5

+101

O 8

Boston Red Sox

BOS

-1.5

-120

U 8

Red Sox Recent Betting Performance

• The Red Sox went 3-3 over the six games they were favored on the moneyline in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Red Sox combined with their opponents to go over the run total four times.
• The Red Sox have put together a 3-7-0 record against the spread over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• O'Neill leads the Red Sox in home runs (seven), runs batted in (eight) and has put up a team-best batting average of .313.
• Including all MLB hitters, O'Neill is 26th in batting average, seventh in on-base percentage, and first in slugging.
• O'Neill has collected a hit in two games in a row. In his last five games he is hitting .250 with a home run, four walks and two RBI.
• Triston Casas has capitalized on opportunities as he leads his team with eight RBI.
• Casas ranks 13th in home runs and 75th in RBI in the majors.
• Jarren Duran is batting .300 with three doubles, a home run and five walks.
• Masataka Yoshida has been productive as he paces his team with eight RBI.

Red Sox Team Props

Learn more about this Red Sox vs. Guardians matchup on Fox Sports.

Guardians Recent Betting Performance

• The Guardians have played as underdogs in six of their past 10 games and won five of those contests.
• The Guardians and their opponents have combined to hit the over five times in their last 10 games with a total.
• The Guardians have won six of their last nine games against the spread.

Guardians Recent Stats

Guardians Player Insights

• Josh Naylor has hit a team-best four home runs.
• In all of the majors, Naylor is 13th in homers and 26th in RBI.
• Naylor brings a hitting streak of three games into this matchup. In his last five games he is batting .389 with two doubles, two home runs, four walks and five RBI.
• Ramirez has totaled 13 runs batted in to pace his team.
• Ramirez is 36th overall in home runs and 16th in RBI this year.
• Steven Kwan leads the Guardians with a team-best batting average of .356.
• Andres Gimenez has five doubles, a triple and three walks while batting .274.

Guardians Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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