Reds vs. Nationals Prediction, Odds, Picks - May 4

James Wood and the Washington Nationals hit the field against Spencer Steer and the Cincinnati Reds on Sunday at 4:10 p.m. ET at Great American Ball Park. The Reds are favored in this one, at -111, while the underdog Nationals have -108 odds to play spoiler. Washington is the favorite on the run line (-1.5). The contest's total has been set at 8.5 runs.

Here is everything you need to know from a betting perspective on the Reds-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Nationals vs. Reds Highlights | MLB on FOX

Check out the best moments between the Washington Nationals and the Cincinnati Reds.

Reds vs. Nationals Game Information & Odds

• When: Sunday, May 4, 2025 at 4:10 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and MASN2

Reds vs. Nationals Prediction

• Score Prediction: Reds 5, Nationals 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Reds 56%, Nationals 44%

Reds vs. Nationals Betting Insights

• This season, the Reds have won 10 out of the 18 games, or 55.6%, in which they've been favored.
• Cincinnati has entered 16 games this season favored by -111 or more and is 9-7 in those contests.
• The moneyline for this contest implies a 52.6% chance of a victory for the Reds.
• The Nationals have been victorious in 13, or 46.4%, of the 28 contests they have been chosen as underdogs in this season.
• This season, Washington has come away with a win 13 times in 28 chances when named as an underdog of at least -108 or worse on the moneyline.
• The Nationals have an implied victory probability of 51.9% according to the moneyline set for this matchup.

Reds Recent Betting Performance

• The Reds played as the moneyline favorite in nine of their last 10 games, and went 6-3 in those matchups.
• In their last 10 matchups (all had set totals), the Reds combined with their opponents to go over the run total four times.
• The Reds have a 6-4-0 record against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz leads the Reds with five home runs and 25 runs batted in.
• De La Cruz ranks 55th in home runs and 12th in RBI among all batters in MLB.
• TJ Friedl is hitting .271 with six doubles, a triple, a home run and 11 walks.
• Friedl ranks 227th in homers and 120th in RBI among all hitters in the majors.
• Friedl has three straight games with at least one hit. During his last five outings he is batting .190 with a walk and an RBI.
• Gavin Lux paces the Reds with a .311 batting average.
• Noelvi Marte is batting .297 with four doubles, a triple, three home runs and five walks.

Reds Team Props

Nationals Recent Betting Performance

• The Nationals have played as underdogs in nine of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Nationals and their opponents are 5-5-0 when it comes to hitting the over.
• The Nationals have a record of 6-4-0 ATS over their last 10 games.

Nationals Recent Stats

Nationals Player Insights

• Wood has swatted a team-high nine long balls.
• Wood's home run total puts him sixth in MLB, and he is 26th in RBI.
• Wood takes a hitting streak of three games into this matchup. In his last five games he is batting .368 with two doubles, five walks and an RBI.
• Nathaniel Lowe has been productive as he paces his team with 27 RBI.
• Among all major league batters, Lowe is 36th in home runs and seventh in RBI.
• Luis Garcia has five doubles, two home runs and eight walks while batting .231.
• Keibert Ruiz leads the Nationals with a team-high batting average of .291.

Nationals Team Props

Nationals vs. Reds Highlights | MLB on FOX

Check out the best moments between the Washington Nationals and the Cincinnati Reds.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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