Twins vs. Guardians Prediction, Odds, Picks - September 6

Updated Sep. 6, 2023 1:07 p.m. ET

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The Minnesota Twins and Royce Lewis will square off against the Cleveland Guardians and Steven Kwan on Wednesday at 1:10 PM ET, in the final of a three-game series at Progressive Field. Bookmakers list the Twins as -127 favorites on the moneyline, while giving the underdog Guardians +107 moneyline odds. Minnesota is the favorite on the run line (-1.5 with +134 odds). An 8-run over/under has been set in this matchup.

The matchup on the mound for this contest is set with the Minnesota Twins looking to Joe Ryan (10-8), and Gavin Williams (1-5) getting the nod for the Cleveland Guardians.

Check out everything you need to know from a betting perspective on the Twins-Guardians game, from the point spread, moneyline, Over/Under and expert picks (odds via FOX Bet):

Twins vs. Guardians Game Information & Odds

• When: Wednesday, September 6, 2023 at 1:10 PM ET
• Where: Progressive Field in Cleveland, Ohio
• How to Watch on TV: MLB Network

Twins vs. Guardians Prediction

• Score Prediction: Guardians 5, Twins 4
• Total Prediction: Over 8 runs
• Win Probabilities: Twins 50%, Guardians 50%

Twins vs. Guardians Betting Insights

• The Twins have been favorites in 93 games this season and won 55 (59.1%) of those contests.
• Minnesota has a record of 42-29 in games when bookmakers favor them by at least -127 on the moneyline.
• The sportsbooks' moneyline implies a 55.9% chance of a victory for the Twins.
• The Guardians have been underdogs in 72 games this season and have come away with the win 31 times (43.1%) in those contests.
• Cleveland has a mark of 21-30 in contests where bookmakers favor it by +107 or worse on the moneyline.
• The moneyline set for this matchup implies the Guardians have a 48.3% chance of coming away with a victory in the contest.

Twins Recent Betting Performance

• The Twins have a 3-2 record across the five games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 outings, the Twins and their opponents combined to hit the over seven times (all 10 of the games had set totals).
• The Twins' ATS record is 7-3-0 over their past 10 games.

Twins Recent Stats

Place your bets on Twins vs. Guardians now with FOX Bet!

Twins Player Insights

• Carlos Correa comes into Wednesday's game as the Twins top run producer, collecting 62 RBI while connecting on 17 home runs in 2023. His .231 average is also best on the squad.
• Correa is 95th in home runs and 84th in RBI among all hitters in the majors.
• Correa has collected a hit in five games in a row. During his last five outings he is hitting .429 with a home run, a walk and five RBI.
• Max Kepler's 21 home runs are a team-high mark.
• Donovan Solano has 25 doubles, a triple, five home runs and 37 walks while batting .294.
• Solano is on a two-game hitting streak entering this contest. In his last five games he is batting .409 with a double, a triple, a home run and six RBI.
• Jorge Polanco is batting .264 with 15 doubles, 12 home runs and 30 walks.
• Polanco brings a two-game streak with at least one hit into this one. In his last five games he is hitting .333 with a double, two home runs, four walks and five RBI.

Twins Team Props

Learn more about this Twins vs. Guardians matchup on Fox Sports.

Guardians Recent Betting Performance

• In 10 games as underdogs over the last 10 matchups, the Guardians have a record of 5-5.
• When it comes to hitting the over, the Guardians and their opponents are 6-4-0 in their last 10 games with a total.
• The Guardians have won five of their last 10 games against the spread.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez leads the Guardians with 21 homers while posting a team-leading batting average of .270.
• In all of the big leagues, Ramirez is 57th in homers and 44th in RBI.
• Kwan is batting .269 with 30 doubles, six triples, five home runs and 54 walks.
• Kwan is currently 294th in home runs and 148th in RBI in the major leagues.
• Josh Naylor has driven in a team-high 80 runs batted in.
• Andres Gimenez has 23 doubles, four triples, 12 home runs and 31 walks while hitting .232.

Guardians Team Props

FOX Bet has the props and odds you need to get your betting on for Twins vs Guardians!

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