Twins vs. Padres Prediction, Odds, Picks - August 21

Updated Aug. 21, 2024 6:00 p.m. ET

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The Minnesota Twins and Carlos Santana ready for the final of a three-game series against Jackson Merrill and the San Diego Padres on Wednesday at PETCO Park. Oddsmakers list the Twins as -122 favorites on the moneyline, while giving the underdog Padres +102 moneyline odds. Minnesota is the favorite on the run line (-1.5). An 8-run total is set for this matchup.

Here's everything you need to know from a betting perspective on the Twins-Padres game, regarding the run line, moneyline and total, plus expert picks.

Padres vs. Twins Highlights | MLB on FOX

Check out the top moments from this game between the San Diego Padres and the Minnesota Twins!

Twins vs. Padres Game Information & Odds

• When: Wednesday, August 21, 2024 at 6:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to Watch on TV: BSN

Twins vs. Padres Prediction

• Score Prediction: Padres 5, Twins 4
• Total Prediction: Over 8 runs
• Win Probabilities: Twins 53%, Padres 47%

Twins vs. Padres Betting Insights

• The Twins have entered the game as favorites 85 times this season and won 53, or 62.4%, of those games.
• Minnesota is 43-26 this season when entering a game favored by -122 or more on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Twins have a 55% chance to win.
• The Padres have been chosen as underdogs in 48 games this year and have walked away with the win 26 times (54.2%) in those games.
• This season, San Diego has come away with a win 13 times in 28 chances when named as an underdog of at least +102 or longer on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Padres have a 49.5% chance of pulling out a win.

FINAL

MIN 11 · SD 4

MLB

RUN LINE

TO WIN

TOTAL

Minnesota Twins

MIN

+1.5

+105

O 8.5

San Diego Padres

SD

-1.5

-127

U 8.5

Twins Recent Betting Performance

• The Twins have a 3-2 record across the five games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 matchups, the Twins and their opponents combined to hit the over five times (all 10 of the games had set totals).
• The Twins' record against the spread is 4-6-0 over their past 10 games.

Twins Recent Stats

Twins Player Insights

• Santana has 23 doubles, 18 home runs and 48 walks while batting .241.
• Among all batters in baseball, Santana is 54th in home runs and 74th in RBI.
• Willi Castro is hitting .253 to pace his team.
• Castro is 159th in homers and 110th in RBI among all major league hitters this year.
• Jose Miranda is hitting .304 with 26 doubles, three triples, nine home runs and 16 walks.
• Ryan Jeffers has put his power on display as he leads his team with 20 home runs and 59 runs batted in.

Twins Team Props

Learn more about this Twins vs. Padres matchup on Fox Sports.

Padres Recent Betting Performance

• Over the past 10 games, the Padres have been underdogs just once and won that contest.
• In their last 10 games with a total, the Padres and their opponents have combined to hit the over six times.
• The Padres have a record of 5-5-0 ATS over their last 10 games.

Padres Recent Stats

Padres Player Insights

• Jurickson Profar leads the Padres in home runs (20) and runs batted in (76).
• Among all hitters in MLB, Profar's home run total is 34th and his RBI tally ranks 22nd.
• Merrill is batting .289 with 21 doubles, six triples, 17 home runs and 21 walks.
• Merrill ranks 70th among all batters in the big leagues in homers, and 34th in RBI.
• Luis Arraez paces the Padres' lineup with a .303 batting average.
• Manny Machado has put up a team-high 20 home runs.

Padres Team Props

Padres vs. Twins Highlights | MLB on FOX

Check out the top moments from this game between the San Diego Padres and the Minnesota Twins!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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