The NFL slate in Week 16 is not one to miss. The matchups include the Philadelphia Eagles playing the Washington Commanders at Commanders Field.

Here are the betting odds to analyze prior to Week 16 in the NFL.

Check out the full NFL football schedule on FOX Sports!

Week 16 Betting Lines & Game Info

Los Angeles Chargers vs. Denver Broncos

Odds & Prediction

• Spread: Chargers (-3)
• Moneyline: Chargers -158, Broncos +133
• Total: 42 points
• Prediction: Broncos 21, Chargers 20

How to Watch

• Game Date: Thursday, Dec. 19
• Game Time: 8:15 p.m. ET
• TV Channel: Amazon Prime Video
• Location: Inglewood, California

Kansas City Chiefs vs. Houston Texans

Odds & Prediction

• Spread: Texans (-2.5)
• Moneyline: Texans -128, Chiefs +108
• Total: 39.5 points
• Prediction: Chiefs 25, Texans 18

How to Watch

• Game Date: Saturday, Dec. 21
• Game Time: 1 p.m. ET
• TV Channel: NBC
• Location: Kansas City, Missouri

Baltimore Ravens vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Ravens (-6)
• Moneyline: Ravens -280, Steelers +228
• Total: 45 points
• Prediction: Ravens 27, Steelers 21

How to Watch

• Game Date: Saturday, Dec. 21
• Game Time: 4:30 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Baltimore, Maryland

New York Jets vs. Los Angeles Rams

Odds & Prediction

• Spread: Rams (-3.5)
• Moneyline: Rams -181, Jets +150
• Total: 46.5 points
• Prediction: Rams 25, Jets 20

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Location: East Rutherford, New Jersey

Indianapolis Colts vs. Tennessee Titans

Odds & Prediction

• Spread: Colts (-4)
• Moneyline: Colts -205, Titans +171
• Total: 42.5 points
• Prediction: Colts 28, Titans 17

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Location: Indianapolis, Indiana

Chicago Bears vs. Detroit Lions

Odds & Prediction

• Spread: Lions (-6.5)
• Moneyline: Lions -292, Bears +235
• Total: 48 points
• Prediction: Lions 32, Bears 15

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Chicago, Illinois

Atlanta Falcons vs. New York Giants

Odds & Prediction

• Spread: Falcons (-10)
• Moneyline: Falcons -521, Giants +388
• Total: 41 points
• Prediction: Falcons 27, Giants 15

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Atlanta, Georgia

Carolina Panthers vs. Arizona Cardinals

Odds & Prediction

• Spread: Cardinals (-4)
• Moneyline: Cardinals -210, Panthers +174
• Total: 47 points
• Prediction: Cardinals 30, Panthers 16

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Charlotte, North Carolina

Washington Commanders vs. Philadelphia Eagles

Odds & Prediction

• Spread: Eagles (-3.5)
• Moneyline: Eagles -171, Commanders +143
• Total: 45.5 points
• Prediction: Eagles 26, Commanders 22

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Landover, Maryland

Cincinnati Bengals vs. Cleveland Browns

Odds & Prediction

• Spread: Bengals (-7)
• Moneyline: Bengals -338, Browns +266
• Total: 48 points
• Prediction: Bengals 30, Browns 19

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Location: Cincinnati, Ohio

Seattle Seahawks vs. Minnesota Vikings

Odds & Prediction

• Spread: Vikings (-3)
• Moneyline: Vikings -165, Seahawks +139
• Total: 43 points
• Prediction: Vikings 25, Seahawks 20

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 4:05 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Seattle, Washington

Buffalo Bills vs. New England Patriots

Odds & Prediction

• Spread: Bills (-14)
• Moneyline: Bills -1031, Patriots +667
• Total: 46.5 points
• Prediction: Bills 36, Patriots 11

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Location: Orchard Park, New York

Miami Dolphins vs. San Francisco 49ers

Odds & Prediction

• Spread: Dolphins (-1.5)
• Moneyline: Dolphins -122, 49ers +102
• Total: 46 points
• Prediction: 49ers 23, Dolphins 21

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Location: Miami Gardens, Florida

Las Vegas Raiders vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Jaguars (-1.5)
• Moneyline: Jaguars -118, Raiders -102
• Total: 39 points
• Prediction: Raiders 23, Jaguars 22

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Location: Paradise, Nevada

Dallas Cowboys vs. Tampa Bay Buccaneers

Odds & Prediction

• Spread: Buccaneers (-4)
• Moneyline: Buccaneers -205, Cowboys +170
• Total: 49.5 points
• Prediction: Buccaneers 31, Cowboys 19

How to Watch

• Game Date: Sunday, Dec. 22
• Game Time: 8:20 p.m. ET
• TV Channel: NBC
• Location: Arlington, Texas

Green Bay Packers vs. New Orleans Saints

Odds & Prediction

• Spread: Packers (-13.5)
• Moneyline: Packers -885, Saints +592
• Total: 42 points
• Prediction: Packers 32, Saints 14

How to Watch

• Game Date: Monday, Dec. 23
• Game Time: 8:15 p.m. ET
• TV Channel: ESPN
• Location: Green Bay, Wisconsin

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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