The matchups in a Week 3 NFL schedule sure to please include the Los Angeles Chargers taking on the Pittsburgh Steelers at Acrisure Stadium.

Check out our betting preview for the NFL's Week 3.

Check out the full NFL football schedule on FOX Sports!

Week 3 Betting Lines & Game Info

New York Jets vs. New England Patriots

Odds & Prediction

• Spread: Jets (-6.5)
• Moneyline: Jets -284, Patriots +228
• Total: 39 points
• Prediction: Patriots 26, Jets 14

How to Watch

• Game Date: Thursday, Sept. 19
• Game Time: 8:15 PM ET
• TV Channel: Amazon Prime Video
• Location: East Rutherford, New Jersey

Pittsburgh Steelers vs. Los Angeles Chargers

Odds & Prediction

• Spread: Steelers (-2.5)
• Moneyline: Steelers -147, Chargers +124
• Total: 36 points
• Prediction: Steelers 15, Chargers 12

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Pittsburgh, Pennsylvania

Minnesota Vikings vs. Houston Texans

Odds & Prediction

• Spread: Texans (-1.5)
• Moneyline: Texans -126, Vikings +106
• Total: 46.5 points
• Prediction: Vikings 23, Texans 17

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Minneapolis, Minnesota

Cleveland Browns vs. New York Giants

Odds & Prediction

• Spread: Browns (-6.5)
• Moneyline: Browns -290, Giants +235
• Total: 38.5 points
• Prediction: Browns 22, Giants 16

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Cleveland, Ohio

Indianapolis Colts vs. Chicago Bears

Odds & Prediction

• Spread: Colts (-1.5)
• Moneyline: Colts -126, Bears +106
• Total: 43.5 points
• Prediction: Colts 20, Bears 19

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Indianapolis, Indiana

Tampa Bay Buccaneers vs. Denver Broncos

Odds & Prediction

• Spread: Buccaneers (-6)
• Moneyline: Buccaneers -262, Broncos +214
• Total: 40.5 points
• Prediction: Buccaneers 22, Broncos 17

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Tampa, Florida

New Orleans Saints vs. Philadelphia Eagles

Odds & Prediction

• Spread: Saints (-2.5)
• Moneyline: Saints -143, Eagles +121
• Total: 49.5 points
• Prediction: Saints 34, Eagles 22

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: New Orleans, Louisiana

Tennessee Titans vs. Green Bay Packers

Odds & Prediction

• Spread: Titans (-3)
• Moneyline: Titans -158, Packers +134
• Total: 37 points
• Prediction: Titans 22, Packers 21

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Nashville, Tennessee

Las Vegas Raiders vs. Carolina Panthers

Odds & Prediction

• Spread: Raiders (-5.5)
• Moneyline: Raiders -246, Panthers +202
• Total: 40 points
• Prediction: Raiders 26, Panthers 16

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 4:05 PM ET
• TV Channel: CBS
• Location: Paradise, Nevada

Seattle Seahawks vs. Miami Dolphins

Odds & Prediction

• Spread: Seahawks (-4)
• Moneyline: Seahawks -203, Dolphins +168
• Total: 41.5 points
• Prediction: Seahawks 26, Dolphins 16

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 4:05 PM ET
• TV Channel: CBS
• Location: Seattle, Washington

Dallas Cowboys vs. Baltimore Ravens

Odds & Prediction

• Spread: Ravens (-1.5)
• Moneyline: Ravens -123, Cowboys +103
• Total: 47.5 points
• Prediction: Cowboys 27, Ravens 26

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Arlington, Texas

Los Angeles Rams vs. San Francisco 49ers

Odds & Prediction

• Spread: 49ers (-6.5)
• Moneyline: 49ers -279, Rams +227
• Total: 44.5 points
• Prediction: 49ers 27, Rams 20

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Inglewood, California

Arizona Cardinals vs. Detroit Lions

Odds & Prediction

• Spread: Lions (-3)
• Moneyline: Lions -153, Cardinals +129
• Total: 51.5 points
• Prediction: Cardinals 27, Lions 22

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Glendale, Arizona

Atlanta Falcons vs. Kansas City Chiefs

Odds & Prediction

• Spread: Chiefs (-3)
• Moneyline: Chiefs -169, Falcons +143
• Total: 46.5 points
• Prediction: Falcons 24, Chiefs 18

How to Watch

• Game Date: Sunday, Sept. 22
• Game Time: 8:20 PM ET
• TV Channel: NBC
• Location: Atlanta, Georgia

Buffalo Bills vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Bills (-4.5)
• Moneyline: Bills -224, Jaguars +184
• Total: 46.5 points
• Prediction: Bills 29, Jaguars 14

How to Watch

• Game Date: Monday, Sept. 23
• Game Time: 7:30 PM ET
• TV Channel: ESPN
• Location: Orchard Park, New York

Cincinnati Bengals vs. Washington Commanders

Odds & Prediction

• Spread: Bengals (-7.5)
• Moneyline: Bengals -357, Commanders +284
• Total: 46 points
• Prediction: Bengals 25, Commanders 18

How to Watch

• Game Date: Monday, Sept. 23
• Game Time: 8:15 PM ET
• TV Channel: ABC
• Location: Cincinnati, Ohio

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

---