In one of the many compelling matchups on the NFL slate in Week 4, the Minnesota Vikings and the Green Bay Packers take the field at Lambeau Field.

To pick up an edge before Week 4 in the NFL, see our betting preview below.

Check out the full NFL football schedule on FOX Sports!

Week 4 Betting Lines & Game Info

New York Giants vs. Dallas Cowboys

Odds & Prediction

• Spread: Cowboys (-5.5)
• Moneyline: Cowboys -249, Giants +202
• Total: 45 points
• Prediction: Cowboys 23, Giants 22

How to Watch

• Game Date: Thursday, Sept. 26
• Game Time: 8:15 p.m. ET
• TV Channel: Amazon Prime Video
• Location: East Rutherford, New Jersey

New York Jets vs. Denver Broncos

Odds & Prediction

• Spread: Jets (-8)
• Moneyline: Jets -402, Broncos +314
• Total: 39.5 points
• Prediction: Broncos 19, Jets 17

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: CBS
• Location: East Rutherford, New Jersey

Chicago Bears vs. Los Angeles Rams

Odds & Prediction

• Spread: Bears (-3)
• Moneyline: Bears -166, Rams +140
• Total: 40.5 points
• Prediction: Rams 22, Bears 21

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Chicago, Illinois

Indianapolis Colts vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Steelers (-2.5)
• Moneyline: Steelers -144, Colts +121
• Total: 40.5 points
• Prediction: Steelers 19, Colts 14

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: CBS
• Location: Indianapolis, Indiana

Green Bay Packers vs. Minnesota Vikings

Odds & Prediction

• Spread: Packers (-2.5)
• Moneyline: Packers -141, Vikings +119
• Total: 44.5 points
• Prediction: Packers 21, Vikings 20

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: CBS
• Location: Green Bay, Wisconsin

Atlanta Falcons vs. New Orleans Saints

Odds & Prediction

• Spread: Falcons (-2.5)
• Moneyline: Falcons -143, Saints +121
• Total: 42 points
• Prediction: Saints 22, Falcons 21

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Atlanta, Georgia

Carolina Panthers vs. Cincinnati Bengals

Odds & Prediction

• Spread: Bengals (-4.5)
• Moneyline: Bengals -233, Panthers +190
• Total: 47 points
• Prediction: Panthers 25, Bengals 24

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Charlotte, North Carolina

Houston Texans vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Texans (-5.5)
• Moneyline: Texans -249, Jaguars +202
• Total: 44.5 points
• Prediction: Texans 25, Jaguars 17

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: CBS
• Location: Houston, Texas

Tampa Bay Buccaneers vs. Philadelphia Eagles

Odds & Prediction

• Spread: Eagles (-1)
• Moneyline: Eagles -117, Buccaneers -102
• Total: 42 points
• Prediction: Buccaneers 23, Eagles 20

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Tampa, Florida

Arizona Cardinals vs. Washington Commanders

Odds & Prediction

• Spread: Cardinals (-3.5)
• Moneyline: Cardinals -180, Commanders +150
• Total: 49 points
• Prediction: Cardinals 30, Commanders 23

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:05 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Glendale, Arizona

San Francisco 49ers vs. New England Patriots

Odds & Prediction

• Spread: 49ers (-10.5)
• Moneyline: 49ers -592, Patriots +433
• Total: 41.5 points
• Prediction: 49ers 25, Patriots 15

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:05 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Santa Clara, California

Las Vegas Raiders vs. Cleveland Browns

Odds & Prediction

• Spread: Browns (-2.5)
• Moneyline: Browns -146, Raiders +123
• Total: 37 points
• Prediction: Raiders 23, Browns 19

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Location: Paradise, Nevada

Los Angeles Chargers vs. Kansas City Chiefs

Odds & Prediction

• Spread: Chiefs (-7)
• Moneyline: Chiefs -355, Chargers +277
• Total: 41 points
• Prediction: Chargers 20, Chiefs 19

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Location: Inglewood, California

Baltimore Ravens vs. Buffalo Bills

Odds & Prediction

• Spread: Ravens (-2.5)
• Moneyline: Ravens -141, Bills +119
• Total: 46.5 points
• Prediction: Ravens 26, Bills 25

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 8:20 p.m. ET
• TV Channel: NBC
• Location: Baltimore, Maryland

Miami Dolphins vs. Tennessee Titans

Odds & Prediction

• Spread: Dolphins (-2.5)
• Moneyline: Dolphins -147, Titans +125
• Total: 37.5 points
• Prediction: Dolphins 21, Titans 18

How to Watch

• Game Date: Monday, Sept. 30
• Game Time: 7:30 p.m. ET
• TV Channel: ESPN
• Location: Miami Gardens, Florida

Detroit Lions vs. Seattle Seahawks

Odds & Prediction

• Spread: Lions (-4.5)
• Moneyline: Lions -216, Seahawks +179
• Total: 47 points
• Prediction: Lions 20, Seahawks 18

How to Watch

• Game Date: Monday, Sept. 30
• Game Time: 8:15 p.m. ET
• TV Channel: ABC
• Location: Detroit, Michigan

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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