In one of the many exciting matchups on the NFL schedule in Week 4, the Buffalo Bills and the Baltimore Ravens hit the field at M&T Bank Stadium.

If you're seeking additional betting information for Week 4 in the NFL, we've got you covered with odds for each of the important games.

Check out the full NFL football schedule on FOX Sports!

Week 4 Betting Lines & Game Info

New York Giants vs. Dallas Cowboys

Odds & Prediction

• Spread: Cowboys (-4.5)
• Moneyline: Cowboys -214, Giants +178
• Total: 44 points
• Prediction: Cowboys 23, Giants 22

How to Watch

• Game Date: Thursday, Sept. 26
• Game Time: 8:15 PM ET
• TV Channel: Amazon Prime Video
• Location: East Rutherford, New Jersey

New York Jets vs. Denver Broncos

Odds & Prediction

• Spread: Jets (-7)
• Moneyline: Jets -345, Broncos +274
• Total: 38.5 points
• Prediction: Broncos 19, Jets 17

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: East Rutherford, New Jersey

Chicago Bears vs. Los Angeles Rams

Odds & Prediction

• Spread: Bears (-3)
• Moneyline: Bears -163, Rams +138
• Total: 41 points
• Prediction: Rams 22, Bears 21

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Chicago, Illinois

Indianapolis Colts vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Steelers (-1.5)
• Moneyline: Steelers -126, Colts +106
• Total: 40 points
• Prediction: Steelers 19, Colts 14

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Indianapolis, Indiana

Tampa Bay Buccaneers vs. Philadelphia Eagles

Odds & Prediction

• Spread: Eagles (-2.5)
• Moneyline: Eagles -139, Buccaneers +117
• Total: 45 points
• Prediction: Buccaneers 23, Eagles 20

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Tampa, Florida

Atlanta Falcons vs. New Orleans Saints

Odds & Prediction

• Spread: Falcons (-1.5)
• Moneyline: Falcons -129, Saints +109
• Total: 42.5 points
• Prediction: Saints 22, Falcons 21

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Atlanta, Georgia

Carolina Panthers vs. Cincinnati Bengals

Odds & Prediction

• Spread: Bengals (-4.5)
• Moneyline: Bengals -212, Panthers +177
• Total: 47.5 points
• Prediction: Panthers 25, Bengals 24

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Charlotte, North Carolina

Houston Texans vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Texans (-6)
• Moneyline: Texans -259, Jaguars +209
• Total: 45.5 points
• Prediction: Texans 25, Jaguars 17

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Houston, Texas

Green Bay Packers vs. Minnesota Vikings

Odds & Prediction

• Spread: Packers (-2.5)
• Moneyline: Packers -141, Vikings +119
• Total: 43.5 points
• Prediction: Packers 21, Vikings 20

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Green Bay, Wisconsin

San Francisco 49ers vs. New England Patriots

Odds & Prediction

• Spread: 49ers (-10)
• Moneyline: 49ers -543, Patriots +400
• Total: 39.5 points
• Prediction: 49ers 25, Patriots 15

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:05 PM ET
• TV Channel: Watch Online: FOX
• Location: Santa Clara, California

Arizona Cardinals vs. Washington Commanders

Odds & Prediction

• Spread: Cardinals (-3.5)
• Moneyline: Cardinals -185, Commanders +155
• Total: 50.5 points
• Prediction: Cardinals 30, Commanders 22

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:05 PM ET
• TV Channel: Watch Online: FOX
• Location: Glendale, Arizona

Las Vegas Raiders vs. Cleveland Browns

Odds & Prediction

• Spread: Raiders (-1)
• Moneyline: Raiders -113, Browns -107
• Total: 37.5 points
• Prediction: Raiders 24, Browns 18

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:25 PM ET
• TV Channel: CBS
• Location: Paradise, Nevada

Los Angeles Chargers vs. Kansas City Chiefs

Odds & Prediction

• Spread: Chiefs (-8)
• Moneyline: Chiefs -397, Chargers +316
• Total: 39 points
• Prediction: Chargers 20, Chiefs 18

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 4:25 PM ET
• TV Channel: CBS
• Location: Inglewood, California

Baltimore Ravens vs. Buffalo Bills

Odds & Prediction

• Spread: Ravens (-2.5)
• Moneyline: Ravens -135, Bills +114
• Total: 46 points
• Prediction: Ravens 26, Bills 25

How to Watch

• Game Date: Sunday, Sept. 29
• Game Time: 8:20 PM ET
• TV Channel: NBC
• Location: Baltimore, Maryland

Miami Dolphins vs. Tennessee Titans

Odds & Prediction

• Spread: Titans (-1.5)
• Moneyline: Titans -111, Dolphins -108
• Total: 37 points
• Prediction: Dolphins 22, Titans 17

How to Watch

• Game Date: Monday, Sept. 30
• Game Time: 7:30 PM ET
• TV Channel: ESPN
• Location: Miami Gardens, Florida

Detroit Lions vs. Seattle Seahawks

Odds & Prediction

• Spread: Lions (-4)
• Moneyline: Lions -201, Seahawks +166
• Total: 46.5 points
• Prediction: Lions 21, Seahawks 18

How to Watch

• Game Date: Monday, Sept. 30
• Game Time: 8:15 PM ET
• TV Channel: ABC
• Location: Detroit, Michigan

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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