The NFL lineup in Week 6, which includes the Tampa Bay Buccaneers versus the New Orleans Saints, is sure to please.

With Week 6 in the NFL upon us, stay on top of the latest betting trends with our preview below.

Check out the full NFL football schedule on FOX Sports!

Week 6 Betting Lines & Game Info

Seattle Seahawks vs. San Francisco 49ers

Odds & Prediction

• Spread: 49ers (-3.5)
• Moneyline: 49ers -196, Seahawks +163
• Total: 48.5 points
• Prediction: Seahawks 24, 49ers 23

How to Watch

• Game Date: Thursday, Oct. 10
• Game Time: 8:15 p.m. ET
• TV Channel: Amazon Prime Video
• Location: Seattle, Washington

Chicago Bears vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Jaguars (-1.5)
• Moneyline: Jaguars -118, Bears -102
• Total: 45 points
• Prediction: Bears 29, Jaguars 15

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 9:30 a.m. ET
• TV Channel: NFL Network
• Location: London, England

Green Bay Packers vs. Arizona Cardinals

Odds & Prediction

• Spread: Packers (-5.5)
• Moneyline: Packers -246, Cardinals +201
• Total: 47.5 points
• Prediction: Packers 29, Cardinals 20

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Green Bay, Wisconsin

New England Patriots vs. Houston Texans

Odds & Prediction

• Spread: Texans (-6.5)
• Moneyline: Texans -288, Patriots +233
• Total: 38 points
• Prediction: Texans 25, Patriots 13

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Location: Foxborough, Massachusetts

New Orleans Saints vs. Tampa Bay Buccaneers

Odds & Prediction

• Spread: Buccaneers (-3.5)
• Moneyline: Buccaneers -182, Saints +152
• Total: 42.5 points
• Prediction: Saints 25, Buccaneers 24

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: New Orleans, Louisiana

Tennessee Titans vs. Indianapolis Colts

Odds & Prediction

• Spread: Titans (-2.5)
• Moneyline: Titans -138, Colts +117
• Total: 42 points
• Prediction: Colts 23, Titans 22

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Location: Nashville, Tennessee

Philadelphia Eagles vs. Cleveland Browns

Odds & Prediction

• Spread: Eagles (-8.5)
• Moneyline: Eagles -441, Browns +332
• Total: 42 points
• Prediction: Eagles 32, Browns 11

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 1 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Philadelphia, Pennsylvania

Baltimore Ravens vs. Washington Commanders

Odds & Prediction

• Spread: Ravens (-6.5)
• Moneyline: Ravens -305, Commanders +243
• Total: 51.5 points
• Prediction: Commanders 28, Ravens 27

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Location: Baltimore, Maryland

Denver Broncos vs. Los Angeles Chargers

Odds & Prediction

• Spread: Chargers (-3)
• Moneyline: Chargers -154, Broncos +129
• Total: 35.5 points
• Prediction: Broncos 19, Chargers 12

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Location: Denver, Colorado

Las Vegas Raiders vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Steelers (-3)
• Moneyline: Steelers -180, Raiders +150
• Total: 36.5 points
• Prediction: Steelers 24, Raiders 15

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Location: Paradise, Nevada

Carolina Panthers vs. Atlanta Falcons

Odds & Prediction

• Spread: Falcons (-6)
• Moneyline: Falcons -265, Panthers +215
• Total: 46 points
• Prediction: Falcons 32, Panthers 15

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 4:25 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Charlotte, North Carolina

Dallas Cowboys vs. Detroit Lions

Odds & Prediction

• Spread: Lions (-3.5)
• Moneyline: Lions -181, Cowboys +152
• Total: 52.5 points
• Prediction: Cowboys 25, Lions 22

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 4:25 p.m. ET
• TV Channel: Watch Online: FOX
• Location: Arlington, Texas

New York Giants vs. Cincinnati Bengals

Odds & Prediction

• Spread: Bengals (-3.5)
• Moneyline: Bengals -210, Giants +175
• Total: 46 points
• Prediction: Giants 26, Bengals 21

How to Watch

• Game Date: Sunday, Oct. 13
• Game Time: 8:20 p.m. ET
• TV Channel: NBC
• Location: East Rutherford, New Jersey

New York Jets vs. Buffalo Bills

Odds & Prediction

• Spread: Bills (-1.5)
• Moneyline: Bills -122, Jets +102
• Total: 41.5 points
• Prediction: Jets 23, Bills 20

How to Watch

• Game Date: Monday, Oct. 14
• Game Time: 8:15 p.m. ET
• TV Channel: ESPN
• Location: East Rutherford, New Jersey

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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