49ers vs. Browns Prediction, Odds, Picks - Oct 15

Published Oct. 11, 2023 1:07 p.m. ET

Data Skrive

The San Francisco 49ers (5-0) will be aiming to extend a five-game winning streak against the Cleveland Browns (2-2). The 49ers are the favorites, expected to win by at least a field goal but less than a touchdown (currently -6.5). The expected point total for the matchup is 37.5.

49ers vs. Browns Odds & Betting Lines

49ers vs Browns Betting Information updated as of October 11, 2023, 12:33 PM ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
49ers	-6.5	-108	-112	37.5	-112	-108

49ers vs. Browns Prediction & Pick

Pick ATS: San Francisco (-6.5)
Pick OU: Over (37.5)
Prediction: San Francisco 25 - Cleveland 15

How to Watch San Francisco vs. Cleveland

Game Date: Sunday, October 15, 2023
Time: 1:00 PM ET
Venue: Cleveland Browns Stadium
Location: Cleveland, Ohio
TV: Watch on FOX

49ers vs. Browns Recent Matchups

Cleveland has a 3-2 record against San Francisco in their last five matchups.
In their last five head-to-head matchups, San Francisco has tallied 80 points versus Cleveland, while surrendering only 70 points.

San Francisco Betting Info

San Francisco has four wins in five games versus the spread this year.
The 49ers have been favored by 6.5 points or more three times this season, and covered the spread in two of those contests.
San Francisco games this year have hit the over on three of five set point totals (60%).
The 49ers have not yet lost a game they were the moneyline favorite, going 5-0 in those matchups this season.
San Francisco has played three times as a moneyline favorite with odds of -270 or shorter, and won in each game.
The 49ers have a 73.0% chance to win this contest, based on the implied probability of the moneyline.

49ers Stats

Stat	Average (Total)	Rank
Pass yards	246.2 (1,231)	8
Rush yards	156.4 (782)	3
Points scored	33.4 (167)	2
Pass yards against	202.6 (1,013)	12
Rush yards against	64.2 (321)	2
Points allowed	13.6 (68)	1

San Francisco's Key Players

Offense

Christian McCaffrey has put up 510 rushing yards (first in the NFL) with seven touchdowns (102 yards per game across five games). His 5.2 yards per attempt rank 10th in the NFL.
McCaffrey has been targeted 24 times in the passing game and has 20 catches (four per game) for 168 yards (33.6 per game) and one TD.
Brock Purdy has passed for 1,271 yards (eighth in the NFL), nine touchdowns (seventh in the NFL) and zero interceptions this year. He averages 254.2 yards per game and 9.3 per attempt, while completing 72.1%.
He has tacked on 24 rushing yards (4.8 per game) and two touchdowns on the ground.
Deebo Samuel has one touchdown catch this season, and has 20 catches for 302 yards on 31 targets, while averaging four catches and 60.4 yards per game.
Brandon Aiyuk averages 5.3 receptions and 94.5 yards per game, and has 378 total receiving yards and 21 catches. He's gotten 27 total targets, and has caught two touchdown passes.

Defense

On the defensive side, Fred Warner has 41 tackles, three TFL, two sacks, and one interception in 2023. His tackle total leads the 49ers.
Dre Greenlaw has one sack (fifth on the 49ers) in addition to his three TFL and 37 tackles.
Deommodore Lenoir has recorded 33 tackles and one interception this year.
Nick Bosa has 1.5 sacks (fourth on the 49ers) to go with four TFL and 12 tackles on the year.

Cleveland Betting Info

Cleveland has covered the spread twice in four games with a set number.
Games involving Cleveland has hit the over once this year.
The Browns have split the two games they've played as underdogs this season.
Cleveland has not been a bigger underdog this season than the +220 moneyline set for this game.
The oddsmakers' moneyline implies a 31.2% chance of a victory for the Browns.

Browns Stats

Stat	Average (Total)	Rank
Pass yards	172.5 (690)	30
Rush yards	143.8 (575)	5
Points scored	19 (76)	30
Pass yards against	125 (500)	1
Rush yards against	71.8 (287)	4
Points allowed	15 (60)	2

Cleveland's Key Players

Offense

Deshaun Watson has thrown for 678 yards this year, with four touchdowns and two interceptions. He is completing 63.7% of his attempts while averaging 226 yards per game and 6.6 per attempt.
Watson has also rushed for one touchdown and 83 yards (third on the Browns).
Jerome Ford has 186 rushing yards (leading the Browns) and one rushing touchdown, while averaging 46.5 yards per game and 3.7 per attempt (31st in the NFL).
Ford has added 10 receptions (2.5 per game) for 77 yards (19.3 per game) with two receiving touchdowns. He's been targeted 13 times in the passing game.
This season, Amari Cooper has caught 18 passes for 259 receiving yards with one touchdown in the passing game. He has been targeted 31 total times and is averaging 4.5 receptions per game in four games played.
Pierre Strong Jr. has scored one touchdown on the ground, while running for 77 total yards (5.9 per carry and 19.3 per game).

Defense

So far in 2023, Myles Garrett has 5.5 sacks to go with five TFL and 10 tackles through four games. He ranks sixth in the NFL in sacks.
Grant Delpit's stats include one interception as well as 21 tackles, one TFL, and two passes defended.
Jeremiah Owusu-Koramoah has 19 tackles and five TFL during the 2023 campaign.
Ogbonnia Okoronkwo's stats include 10 tackles, five TFL, and 2.5 sacks in four games