49ers vs. Cardinals 2024 Prediction, Odds, Picks - Oct 6

Published Oct. 4, 2024 4:43 p.m. ET

Data Skrive

The San Francisco 49ers (2-2) are solid favorites -- expected to win by at least a touchdown (currently -7) -- against the Arizona Cardinals (1-3) in a battle of two division rivals. The total for this one is set at 50 points.

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49ers vs. Cardinals Odds & Betting Lines

49ers vs Cardinals Betting Information updated as of October 4, 2024, 4:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
49ers	-7	-115	-105	50	-108	-112

49ers vs. Cardinals Prediction & Pick

Pick ATS: 49ers (-7)
Pick OU: Under (50)
Prediction: 49ers 31 - Cardinals 18

How to Watch San Francisco vs. Arizona

Game Date: Sunday, October 6, 2024
Time: 4:05 p.m. ET
Venue: Levi's Stadium
Location: Santa Clara, California
TV: Watch on FOX
Live Boxscore: FOX Sports

49ers vs. Cardinals Recent Matchups

Over their last five meetings, San Francisco has collected four wins versus Arizona.
In their last five head-to-head matchups, San Francisco has tallied 173 points against Arizona, while surrendering only 99 points.

San Francisco Betting Info

San Francisco has two wins versus the spread in four games this year.
The 49ers have won their only game this season when playing as at least 7-point favorites.
San Francisco games this year have hit the over on three of four set point totals (75%).
When playing as the moneyline favorite, the 49ers have won 50% of the time (2-2).
The 49ers have a 78.0% chance to win this game, based on the implied probability of the moneyline.

49ers Stats

Stat	Average (Total)	Rank
Pass yards	271.5 (1,086)	2
Rush yards	141.8 (567)	8
Points scored	25.8 (103)	10
Pass yards against	199 (796)	15
Rush yards against	96.3 (385)	6
Points allowed	20.5 (82)	9

San Francisco's Key Players

Offense

Jordan Mason has totaled 447 rushing yards (second in the NFL) with three touchdowns (111.8 yards per game across four games). His 4.9 yards per attempt rank 14th in the NFL.
Mason has seven targets, six catches, 57 receiving yards and zero TDs in the passing game.
Brock Purdy has 1,130 passing yards (fourth in the NFL), five touchdowns and two interceptions this year. He has completed 68.9% of his passes, averaging 282.5 yards per game and 9.3 per attempt.
He has added 75 rushing yards (18.8 per game) without a touchdown on the ground.
Jauan Jennings has three touchdown catches this season (fourth in the NFL), and has 21 receptions for 364 yards (fifth in the NFL) on 27 targets, while averaging 5.3 catches and 91.0 yards per game.
Deebo Samuel averages 5.3 receptions and 74.0 yards per game, and has 222 total receiving yards and 16 catches. He's gotten 24 total targets, but has yet to record a touchdown pass.

Defense

On defense for the 49ers, Fred Warner has put up 27 tackles, 1.0 TFL, one sack, and two interceptions in 2024.
Nick Bosa has 14 tackles, 4.0 TFL, and three sacks.
Maliek Collins has collected 10 tackles, 2.0 TFL, and 2.5 sacks this year.
Ji'Ayir Brown has 2.0 TFL and 20 tackles this year.

Arizona Betting Info

Arizona has registered a win-loss record of 2-2-0 against the spread this year.
Arizona's games have finished with a final combined score above the over/under three times this year.
The Cardinals have lost both games they've played as underdogs this season.
The oddsmakers' moneyline implies a 26.3% chance of a victory for the Cardinals.

Cardinals Stats

Stat	Average (Total)	Rank
Pass yards	179.8 (719)	25
Rush yards	153.3 (613)	5
Points scored	24 (96)	14
Pass yards against	208.3 (833)	17
Rush yards against	146.5 (586)	27
Points allowed	26.5 (106)	29

Arizona's Key Players

Offense

Kyler Murray has thrown for 777 yards this year, with six touchdowns (sixth in the NFL) and one interception. He is completing 69.4% of his passes while averaging 194.3 yards per game and 7.2 per attempt.
Murray has also rushed for 164 yards (second on the Cardinals).
James Conner averages 73.3 rushing yards per game over four games (293 total yards), while scoring three rushing touchdowns.
Conner has added six receptions (1.5 per game) for 52 yards (13.0 per game), without a receiving touchdown. He's been targeted seven times in the passing game.
Marvin Harrison Jr. has registered 243 receiving yards and four touchdowns (second in the NFL) on 15 receptions, while being targeted 28 times this season.
Michael Wilson has 138 receiving yards and one touchdown from 14 receptions after receiving 20 targets.

Defense

In 2024, Budda Baker has amassed 39 tackles and 3.0 TFL over four games.
Dennis Gardeck has 14 tackles, 5.0 TFL, three sacks, and one interception.
Mack Wilson has 27 tackles, 2.0 TFL, and one sack in the 2024 season. He is fourth on the Cardinals in tackles.
Kyzir White has 38 tackles and 1.0 TFL.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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