Data Skrive
In a matchup of two division rivals, the San Francisco 49ers (1-1) will meet the Los Angeles Rams (0-2). The 49ers are the favorites, expected to win by at least a field goal but less than a touchdown (currently -6). The over/under for this one is set at 44.5 points.
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49ers vs. Rams Odds & Betting Lines
| Favorite | Spread | Favorite Spread Odds | Underdog Spread Odds | Total | Over Total Odds | Under Total Odds |
|---|---|---|---|---|---|---|
| 49ers | -6 | -112 | -108 | 44.5 | -108 | -112 |
49ers vs. Rams Prediction & Pick
- Pick ATS: Rams (+6)
- Pick OU: Over (44.5)
- Prediction: 49ers 25 - Rams 22
How to Watch San Francisco vs. Los Angeles
- Game Date: Sunday, September 22, 2024
- Time: 4:25 p.m. ET
- Venue: SoFi Stadium
- Location: Inglewood, California
- TV: Watch on FOX
- Live Boxscore: FOX Sports
Read More About This Game
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49ers vs. Rams Recent Matchups
- In their last five head-to-head bouts, San Francisco has won against Los Angeles three times.
- Los Angeles has been outpaced by 35 points in its last five tilts versus San Francisco.
San Francisco Betting Info
- San Francisco has covered the spread one time this year.
- San Francisco games this year have gone over the total in one out of two opportunities (50%).
- The 49ers have been moneyline favorites in two other matchups this season, and they split them.
- Looking at this matchup's moneyline, the 49ers' implied win probability is 73.0%.
49ers Stats
| Stat | Average (Total) | Rank |
|---|---|---|
| Pass yards | 257.5 (515) | 3 |
| Rush yards | 141 (282) | 11 |
| Points scored | 24.5 (49) | 10 |
| Pass yards against | 227.5 (455) | 22 |
| Rush yards against | 107 (214) | 12 |
| Points allowed | 21 (42) | 16 |
San Francisco's Key Players
Offense
- On the ground, Jordan Mason averages 5.1 yards per attempt (14th in the NFL) and 123.5 yards per game for 247 total rushing yards (second in the NFL). He has recorded two rushing touchdowns this season.
- Brock Purdy has 550 passing yards (second in the NFL), one touchdown and one interception this year. He has completed 72.3% of his attempts, averaging 275 yards per game and 8.5 per attempt.
- He has tacked on 23 rushing yards (11.5 per game) without a touchdown on the ground.
- Deebo Samuel is still looking for his first touchdown catch, but has 13 catches for 164 yards (10th in the NFL) on 19 targets, while averaging 6.5 catches and 82 yards per game.
- George Kittle averages 5.5 receptions and 58 yards per game, and has 116 total receiving yards and 11 catches. He's gotten 13 total targets, and has caught one touchdown pass.
Defense
- On defense, Fred Warner has one sack (second on the 49ers) to go with one TFL, 16 tackles, and one interception in 2024.
- Nick Bosa has seven tackles, two TFL, and two sacks this season. He's fifth on the 49ers in tackles.
- Isaac Yiadom has recorded seven tackles this year. He's fifth on the 49ers in tackles.
- This season, Deommodore Lenoir has 10 tackles.
Los Angeles Betting Info
- Los Angeles has not covered the spread yet this season (0-2-0).
- This season, Los Angeles games have hit the over just once.
- The Rams lost the only game they've played as the underdog this season.
- The Rams have a 31.2% chance to win this game based on the implied probability of the moneyline.
Rams Stats
| Stat | Average (Total) | Rank |
|---|---|---|
| Pass yards | 248 (496) | 5 |
| Rush yards | 68 (136) | 31 |
| Points scored | 15 (30) | 27 |
| Pass yards against | 229 (458) | 24 |
| Rush yards against | 197 (394) | 30 |
| Points allowed | 33.5 (67) | 31 |
Los Angeles' Key Players
Offense
- Kyren Williams averages 37.5 rushing yards per game this year (75 total yards), while scoring two rushing touchdowns.
- On top of his impact in the run game, Williams has caught seven passes (on eight targets) for 31 yards (seventh on the Rams). He's averaging 15.5 yards per game.
- Cooper Kupp has put together a 2024 campaign that includes 18 catches (first in the NFL) for 147 yards and one receiving touchdown over two games played. He has been on the receiving end of 27 targets and is averaging nine receptions per game.
- Matthew Stafford has thrown for 533 yards this year (to rank third in the NFL), one touchdown and one interception. He is completing 69.7% of his passes while averaging 266.5 yards per game and 7 per attempt.
- Tyler Johnson has 99 receiving yards from seven receptions after receiving 10 targets.
Defense
- Jared Verse's 2024 effort includes 11 tackles, four TFL, and one sack through two games. He is fifth on the Rams in tackles.
- Quentin Lake has 21 tackles.
- Over the 2024 campaign, Troy Reeder has 16 tackles through two games.
- Byron Young has one sack (first on the Rams) to go with two TFL and six tackles over two games.
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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