49ers vs. Rams Prediction, Odds, Picks - Jan 7

Published Jan. 3, 2024 1:06 p.m. ET

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The San Francisco 49ers (12-4) are the favorites, expected to win by at least a field goal but less than a touchdown (currently -3.5) over the Los Angeles Rams (9-7), despite the Rams having won three games in a row. The predicted point total for the game is 42.

49ers vs. Rams Odds & Betting Lines

49ers vs. Rams Prediction & Pick

• Pick ATS: San Francisco (-3.5)
  
• Pick OU: Over (42)
  
• Prediction: San Francisco 29 - Los Angeles 17

How to Watch San Francisco vs. Los Angeles

• Game Date: Sunday, January 7, 2024
• Time: 4:25 PM ET
• Venue: Levi's Stadium
• Location: Santa Clara, California
• TV: Watch on FOX

49ers vs. Rams Recent Matchups

• San Francisco owns a 5-0 record against Los Angeles in their last five matchups.
• In their last five head-to-head matchups, San Francisco has racked up 139 points against Los Angeles, while allowing only 84 points.

San Francisco Betting Info

• San Francisco has played 16 games, posting nine wins against the spread.
• The 49ers have covered the spread six times this season (6-7 ATS) when playing as at least 3.5-point favorites.
• San Francisco contests this year have eclipsed the over/under 50% of the time (eight times in 16 games with a set point total).
• When playing as moneyline favorites, the 49ers are 12-4, earning a win 75% of the time.
• San Francisco has an 8-4 record (winning 66.7% of its games) when playing as a moneyline favorite of -192 or shorter.
• The 49ers have an implied win probability, based on the moneyline, of 65.8%.

49ers Stats

San Francisco's Key Players

Offense

• Christian McCaffrey has collected 1,459 rushing yards (first in the NFL) with 14 touchdowns (91.2 yards per game across 16 games). His 5.4 yards per attempt rank second in the league.
• McCaffrey has been targeted 83 times in the receiving game and has 67 catches (4.2 per game) for 564 yards (35.3 per game) and seven TDs.
• Brock Purdy has passed for 4,280 yards (second in the NFL), 31 touchdowns (second in the NFL) and 11 interceptions this year. He averages 267.5 yards per game and 9.6 per attempt, while completing 69.4%.
• He has also rushed for 144 yards (fifth on the 49ers) and added two touchdowns on the ground, while averaging 9.0 rushing yards per game.
• Through 14 games played, Deebo Samuel is averaging 62.2 yards and 4.1 receptions per game on the way to 871 receiving yards and 58 catches. He's been targeted 87 times, and has seven receiving touchdowns.
• Brandon Aiyuk has 1,317 receiving yards (sixth in the NFL) and seven touchdowns with 72 catches on 101 targets. He is averaging 4.8 receptions and 87.8 yards per game.

Defense

• On the defensive side, Fred Warner has 2.5 sacks to go with 6.0 TFL, 132 tackles, and four interceptions in 2023.
• Nick Bosa has 52 tackles, 16.0 TFL, and 10.5 sacks this season.
• Dre Greenlaw has put up 120 tackles, 5.0 TFL, and 1.5 sacks this year.
• This season, Charvarius Ward has 68 tackles, 2.0 TFL, and five interceptions.

Los Angeles Betting Info

• Los Angeles is 9-6-1 against the spread this year.
• This season, the Rams have an ATS record of 3-3 in their six games as an underdog of 3.5 points or more.
• This year, eight Los Angeles games have gone over the point total.
• The Rams have been underdogs in seven games this season and won one (14.3%) of those contests.
• Los Angeles has entered four games this season as the underdog by +160 or more and is 1-3 in those contests.
• The moneyline for this contest implies a 38.5% chance of a victory for the Rams.

Rams Stats

Los Angeles' Key Players

Offense

• Matthew Stafford has thrown for 3,965 yards this year (to rank sixth in the NFL), with 24 touchdowns (10th in the NFL) and 11 interceptions. He is completing 62.6% of his attempts while averaging 264.3 yards per game and 7.6 per attempt.
• Kyren Williams has scored 12 rushing touchdowns, while totaling 1,144 rushing yards (5.0 per carry and 95.3 per game).
• Williams also has 32 catches for 206 yards (sixth on the Rams), with three receiving touchdowns. He has been targeted 48 times and averages 17.2 yards per game.
• Puka Nacua has recorded 1,445 receiving yards (fourth in the NFL) and five touchdowns on 101 receptions (eighth in the NFL), while being targeted 154 times this season.
• Cooper Kupp has 59 catches for 737 yards and five receiving touchdowns. He averages 4.9 yards per game in 12 games and has been targeted 95 times.

Defense

• Ernest Jones has 4.5 sacks (fifth on the Rams) to go with 14.0 TFL and 145 tackles through 15 games in 2023.
• Jordan Fuller has 1.0 TFL, 92 tackles, and three interceptions.
• During the 2023 season, Aaron Donald has 53 tackles, 16.0 TFL, and eight sacks through 16 games.
• Byron Young has 60 tackles, 7.0 TFL, and seven sacks.

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