49ers vs. Seahawks 2024 Prediction, Odds, Picks - Nov 17

Updated Nov. 17, 2024 12:50 p.m. ET

Data Skrive

The San Francisco 49ers (5-4) are the favorites -- expected to win by at least a field goal, but less than a touchdown (currently -6) -- versus the Seattle Seahawks (4-5) in a matchup of two division rivals. The expected point total for the matchup is set at 48.5.

Keep up with the 2024 NFL season on FOX Sports.

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49ers vs. Seahawks Odds & Betting Lines

49ers vs Seahawks Betting Information updated as of November 17, 2024, 11:34 a.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
49ers	-6	-108	-112	48.5	-112	-108

49ers vs. Seahawks Prediction & Pick

Pick ATS: 49ers (-6)
Pick OU: Under (48.5)
Prediction: 49ers 28 - Seahawks 20

How to Watch San Francisco vs. Seattle

Game Date: Sunday, November 17, 2024
Time: 4:05 p.m. ET
Venue: Levi's Stadium
Location: Santa Clara, California
TV: Watch on FOX
Live Boxscore: FOX Sports

49ers vs. Seahawks Recent Matchups

San Francisco has a 5-0 record against Seattle in their last five matchups.
Over their last five head-to-head contests, San Francisco has scored 157 points, while Seattle has compiled 89.

San Francisco Betting Info

San Francisco has four wins in nine games versus the spread this year.
The 49ers have been favored by 6 points or more four times this season, and covered the spread in one of those contests.
San Francisco games this year have gone over the total in five out of nine opportunities (55.6%).
The 49ers have put together a 5-4 record in games they played as moneyline favorite (winning 55.6% of those games).
Based on this contest's moneyline, the 49ers' implied win probability is 72.1%.

49ers Stats

Stat	Average (Total)	Rank
Pass yards	262.8 (2,365)	2
Rush yards	149.7 (1,347)	4
Points scored	25.9 (233)	10
Pass yards against	197.4 (1,777)	12
Rush yards against	106.2 (956)	8
Points allowed	22.4 (202)	17

San Francisco's Key Players

Offense

Brock Purdy ranks sixth in the NFL with 2,454 passing yards through nine games this year, averaging 272.7 per game with a 65.1% completion percentage and 12 touchdowns (10th in the NFL) against seven interceptions.
He has added 227 rushing yards (25.2 per game) and three touchdowns on the ground.
George Kittle has caught 43 passes on 53 targets for 560 total yards and seven touchdowns. He is averaging 5.4 catches and 70 yards per game through eight games.
Jordan Mason has 690 rushing yards (ninth in the NFL) with three touchdowns (76.7 yards per game across nine games).
Jauan Jennings averages 4.6 receptions and 71 yards per game, and has 497 total receiving yards and 32 catches. He's gotten 47 total targets, and has caught three touchdown passes.

Defense

Over on defense, Fred Warner has 75 tackles, three TFL, one sack, and two interceptions in 2024.
Nick Bosa has 32 tackles, eight TFL, 5.5 sacks, and one interception this season.
Deommodore Lenoir has collected 53 tackles, one TFL, and two interceptions this year.
Ji'Ayir Brown has one interception while tacking on 45 tackles, three TFL, and four passes defended.

Seattle Betting Info

Seattle is 2-7-0 against the spread this year.
Seattle games have gone over the total five times this season.
The Seahawks have won one of the five games they've played as underdogs this season.
Oddsmakers have implied with the moneyline set for this matchup that the Seahawks have a 32.3% chance to win.

Seahawks Stats

Stat	Average (Total)	Rank
Pass yards	268.2 (2,414)	1
Rush yards	91.2 (821)	27
Points scored	23.3 (210)	17
Pass yards against	218.1 (1,963)	20
Rush yards against	139.4 (1,255)	26
Points allowed	24.6 (221)	23

Seattle's Key Players

Offense

Geno Smith has passed for 2,560 yards this year (to rank fourth in the NFL), with 11 touchdowns and 10 interceptions. He is completing 68.1% of his attempts while averaging 284.4 yards per game and 7.5 per attempt.
He's added 193 yards on the ground (third on the Seahawks), with one rushing touchdown. He's averaging 21.4 yards per game and 5.4 per attempt.
Kenneth Walker III averages 56.9 rushing yards per game through seven games (398 total yards), while scoring six rushing touchdowns.
Walker has also collected 217 receiving yards (31 per game) on 30 catches (4.3 per game). He's been targeted 34 times and has caught one touchdown pass.
Jaxon Smith-Njigba has totaled 568 receiving yards and three touchdowns on 50 receptions, while being targeted 75 times on the season.
D.K. Metcalf has been targeted 61 times, resulting in 35 catches for 568 yards .

Defense

Julian Love has put up two TFL, 65 tackles, and two interceptions over nine games in 2024.
Ernest Jones has 68 tackles, four TFL, and three passes defended.
During the 2024 campaign, Derick Hall has 25 tackles, three TFL, and five sacks in nine games.
Devon Witherspoon has totaled one TFL and 51 tackles over nine games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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