49ers vs. Seahawks Prediction, Odds, Picks - Nov 23

Published Nov. 20, 2023 1:03 a.m. ET

Data Skrive

The San Francisco 49ers (7-3) and Seattle Seahawks (6-4) will meet in a matchup of two division rivals. The 49ers are solid favorites, expected to win by at least a touchdown (currently -7). The expected point total for the game is 42.5.

49ers vs. Seahawks Odds & Betting Lines

49ers vs Seahawks Betting Information updated as of November 19, 2023, 9:33 PM ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
49ers	-7	-110	-110	42.5	-110	-110

49ers vs. Seahawks Prediction & Pick

Pick ATS: San Francisco (-7)
Pick OU: Over (42.5)
Prediction: San Francisco 27 - Seattle 17

How to Watch San Francisco vs. Seattle

Game Date: Thursday, November 23, 2023
Time: 8:20 PM ET
Venue: Lumen Field
Location: Seattle, Washington
TV: Watch on NBC

49ers vs. Seahawks Recent Matchups

Over their last five meetings, San Francisco has tallied four wins versus Seattle.
Seattle has been outscored by 48 points in its last five tilts versus San Francisco.

San Francisco Betting Info

San Francisco has played 10 games, posting five wins against the spread.
The 49ers have covered the spread twice this season (2-4 ATS) when playing as at least 7-point favorites.
San Francisco games this year have gone over the total in four out of 10 opportunities (40%).
When playing as moneyline favorites, the 49ers are 7-3 (winning 70% of the time).
San Francisco is 4-2 (winning 66.7% of its games) when playing as a moneyline favorite of -310 or shorter.
The 49ers have a 75.6% chance to win this contest, based on the implied probability of the moneyline.

49ers Stats

Stat	Average (Total)	Rank
Pass yards	254.3 (2,543)	8
Rush yards	132.7 (1,327)	6
Points scored	27.9 (279)	5
Pass yards against	221.4 (2,214)	15
Rush yards against	81.4 (814)	3
Points allowed	15.7 (157)	1

San Francisco's Key Players

Offense

On the ground, Christian McCaffrey averages 4.7 yards per attempt (ninth in the NFL) and 82.5 yards per game for 825 total rushing yards (first in the NFL). He has scored nine rushing touchdowns this season.
He's also hauled in 43 passes (on 52 targets) for 364 receiving yards with five touchdowns. He's averaging 36.4 receving yards and 4.3 catches per game.
Brock Purdy has 2,662 passing yards (sixth in the NFL), 18 touchdowns (fifth in the NFL) and five interceptions this year. He has completed 70.2% of his passes, averaging 266.2 yards per game and 9.7 per attempt.
He has also rushed for 121 yards (third on the 49ers) and added two touchdowns on the ground, while averaging 12.1 rushing yards per game.
In nine games played, Brandon Aiyuk is averaging 92.3 yards and 4.8 receptions per game to total 831 receiving yards (10th in the NFL) and 43 catches. He's been targeted 61 times, and has four receiving touchdowns.
George Kittle averages 4.3 receptions and 64.8 yards per game, and has 648 total receiving yards and 43 catches. He's gotten 56 total targets, and has caught five touchdown passes.

Defense

On the defensive side, Fred Warner has 90 tackles, 5.0 TFL, 2.5 sacks, and three interceptions in 2023.
Dre Greenlaw has 71 tackles, 5.0 TFL, and 1.5 sacks this season.
Nick Bosa has totaled 28 tackles, 7.0 TFL, and 5.5 sacks this year.
So far this season, Charvarius Ward has 46 tackles, 1.0 TFL, and two interceptions. He's fifth on the 49ers in tackles.

Seattle Betting Info

Seattle is 5-4-1 against the spread this year.
Seattle's games have finished with a final combined score above the over/under four times this year.
The Seahawks have entered the game as underdogs four times this season and won once.
Seattle has not entered a game this season with longer moneyline odds than +250.
The oddsmakers' moneyline implies a 28.6% chance of a victory for the Seahawks.

Seahawks Stats

Stat	Average (Total)	Rank
Pass yards	230.8 (2,308)	13
Rush yards	96.6 (966)	25
Points scored	21.6 (216)	16
Pass yards against	233.0 (2,330)	21
Rush yards against	112.6 (1,126)	19
Points allowed	21.8 (218)	19

Seattle's Key Players

Offense

Through 10 games played this year, Geno Smith has amassed 2,404 passing yards, while throwing 12 touchdowns against seven interceptions and completing 65.3% of his attempts.
Kenneth Walker III has 613 rushing yards (leading the Seahawks and 10th in the NFL) and six rushing touchdowns, while averaging 61.3 yards per game and 4.1 per attempt (18th in the NFL).
Walker has also collected 173 receiving yards (17.3 per game) on 17 catches (1.7 per game). He's been targeted 23 times and has caught one touchdown pass.
D.K. Metcalf has put up 646 receiving yards and three touchdowns on 40 receptions, while being targeted 71 times on the season.
Tyler Lockett has 545 receiving yards and four touchdowns from 51 receptions after getting 74 targets.

Defense

Bobby Wagner has recorded 2.5 sacks (fifth on the Seahawks) to go with 5.0 TFL and 105 tackles over 10 games in 2023.
Jordyn Brooks' stats include 83 tackles, 7.0 TFL, 3.5 sacks, and two passes defended.
In the 2023 campaign, Devon Witherspoon has 52 tackles, 3.0 TFL, three sacks, and one interception in nine games.
Boye Mafe's stats include 32 tackles, 7.0 TFL, seven sacks, and three passes defended in nine games